E-viri
Recenzirano
Odprti dostop
-
Andersen, Vibeke; Chan, Simon; Luben, Robert; Khaw, Kay-Tee; Olsen, Anja; Tjonneland, Anne; Kaaks, R; Grip, Olof; Bergmann, M M; Boeing, H; Hultdin, Johan; Karling, Pontus; Overvad, Kim; Oldenburg, Bas; Opstelten, Jorrit; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Racine, Antoine; Key, Timothy; Masala, Giovanna; Palli, Domenico; Tumino, R; Trichopoulou, A; Riboli, Elio; Hart, Andrew
Journal of Crohn's and colitis, 01/2018, Letnik: 12, Številka: 2Journal Article
Abstract Background and Aims Population-based prospective cohort studies investigating fibre intake and development of inflammatory bowel disease are lacking. Our aim was to investigate the association between fibre intake and the development of Crohn’s disease CD and ulcerative colitis UC in a large European population. Methods In total, 401326 participants, aged 20–80 years, were recruited in eight countries in Europe between 1991 and 1998. At baseline, fibre intake total fibres, fibres from fruit, vegetables and cereals was recorded using food frequency questionnaires. The cohort was monitored for the development of inflammatory bowel disease. Each case was matched with four controls and odds ratios ORs for the exposures were calculated using conditional logistic regression. Sensitivity analyses according to smoking status were computed. Results In total, 104 and 221 participants developed incident CD and UC, respectively. For both CD and UC, there were no statistically significant associations with either quartiles, or trends across quartiles, for total fibre or any of the individual sources. The associations were not affected by adjusting for smoking and energy intake. Stratification according to smoking status showed null findings apart from an inverse association with cereal fibre and CD in non-smokers Quartile 4 vs 1 OR = 0.12, 95% confidence interval = 0.02–0.75, p = 0.023, OR trend across quartiles = 0.50, 95% confidence interval = 0.29–0.86, p = 0.017. Conclusion The results do not support the hypothesis that dietary fibre is involved in the aetiology of UC, although future work should investigate whether there may be a protective effect of specific types of fibre according to smoking status in CD.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.