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Hidestrand, Mats, PhD; Tomita-Mitchell, Aoy, PhD; Hidestrand, Pip M., MD; Oliphant, Arnold, PhD; Goetsch, Mary, MS; Stamm, Karl, MS; Liang, Huan-Ling, MD; Castleberry, Chesney, MD; Benson, D. Woodrow, MD, PhD; Stendahl, Gail, DNP; Simpson, Pippa M., PhD; Berger, Stuart, MD; Tweddell, James S., MD; Zangwill, Steven, MD; Mitchell, Michael E., MD
Journal of the American College of Cardiology, 04/2014, Letnik: 63, Številka: 12Journal Article
Rejection from heart transplant recipients with biopsy- proven rejection (> The International Society for Heart and Lung Transplantation grade 2R or antibody mediated rejection 1) before initiation of treatment, during treatment, and at 1 week. The DScf-DNA was compared with other candidate noninvasive laboratory variables (B-natriuretic peptide, troponin, and C-reactive protein) as well as echocardiographically determined left ventricular ejection fraction in predicting rejection on biopsy; DScf-DNA had the highest sensitivity and specificity (100% and 84%, respectively).
