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  • Recovery of functional fitn...
    Xiong, Lijuan; Li, Qian; Cao, Xiongjing; Xiong, Huangguo; Huang, Ming; Yang, Fengwen; Meng, Daquan; Zhou, Mei; Zhang, Yanzhao; Fan, Yunzhou; Tang, Liang; Jin, Yang; Xia, Jiahong; Hu, Yu

    International journal of infectious diseases, 10/2022, Letnik: 123
    Journal Article

    •COVID-19 can cause a series of clinical symptoms.•The lung is the organ most affected by infection of SARS-CoV-2.•Interventions should be implemented to help recovery of healthcare workers with COVID-19. This study aimed to evaluate the recovery of functional fitness, lung function, and immune function in healthcare workers (HCWs) with nonsevere and severe COVID-19 at 13 months after discharge from the hospital. The participants of “Rehabilitation Care Project for Medical Staff Infected with COVID-19” underwent a functional fitness test (muscle strength, flexibility, and agility/dynamic balance), lung function test, and immune function test (including cytokines and lymphocyte subsets) at 13 months after discharge. The project included 779 HCWs (316 nonsevere COVID-19 and 463 severe COVID-19). This study found that 29.1% (130/446) of the HCWs have not yet recovered their functional fitness. The most affected lung function indicator was lung perfusion capacity (34% with diffusion capacity for carbon monoxide-single breath <80%). The increase of interleukin-6 (64/534, 12.0%) and natural killer cells (44/534, 8.2%) and the decrease of CD3+ T cells (58/534, 10.9%) and CD4+ T cells (26/534, 4.9%) still existed at 13 months after discharge. No significant difference was found in the HCWs with nonsevere and severe COVID-19 regarding recovery of functional fitness, lung function, and immune function at 13 months after discharge. The majority of Chinese HCWs with COVID-19 had recovered their functional fitness, lung function, and immune function, and the recovery status in HCWs with severe COVID-19 is no worse than that in HCWs with nonsevere COVID-19 at 13 months after discharge from the hospital.