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Corrado, Domenico, MD, PhD; Basso, Cristina, MD, PhD; Leoni, Loira, MD, PhD; Tokajuk, Barbara, MD, PhD; Turrini, Pietro, MD, PhD; Bauce, Barbara, MD, PhD; Migliore, Federico, MD; Pavei, Andrea, MD; Tarantini, Giuseppe, MD, PhD; Napodano, Massimo, MD; Ramondo, Angelo, MD; Buja, Gianfranco, MD; Iliceto, Sabino, MD; Thiene, Gaetano, MD
Journal of the American College of Cardiology, 02/2008, Letnik: 51, Številka: 7Journal Article
Three-Dimensional Electroanatomical Voltage Mapping and Histologic Evaluation of Myocardial Substrate in Right Ventricular Outflow Tract Tachycardia Domenico Corrado, Cristina Basso, Loira Leoni, Barbara Tokajuk, Pietro Turrini, Barbara Bauce, Federico Migliore, Andrea Pavei, Giuseppe Tarantini, Massimo Napodano, Angelo Ramondo, Gianfranco Buja, Sabino Iliceto, Gaetano Thiene Twenty-seven patients (15 men and 12 women, age 33.9 ± 8 years) with right ventricular outflow tract (RVOT) tachycardia and no right ventricular (RV) dilation/dysfunction were studied by electroanatomical voltage mapping (EVM) and endomyocardial biopsy (EMB) before catheter ablation. Right ventricular EVM was normal in 20 of 27 patients (74%, group A), whereas the other 7 patients (26%, group B) showed RVOT electroanatomical scars that correlated with fibrofatty myocardial replacement at EMB (p < 0.001). Three of 7 patients (43%) from group B received an implantable defibrillator during the follow-up, compared with no patients from group A (p = 0.012). Electroanatomical voltage mapping is able to identify RVOT tachycardia due to concealed arrhythmogenic RV cardiomyopathy/dysplasia.
