Introduction: Colon capsule endoscopy (CCE) is a new technology with two approved indications; to provide visualization of the colon after an incomplete colonoscopy and second, to detect pathology in patients with evidence of lower gastrointestinal bleeding. Training physicians to properly implement this technology is critical. Our hypothesis is that participants in a live, in-person training for Pillcam Colon achieve increased levels of comfort with the indications, contraindications and reading after course completion. Methods: We conducted a prospective study comparing surveys administered prior to and after an educational training session on PC. The educational session was an eight hour course designed to teach providers how to read the PC studies effectively. The data was pooled from two separate educational sessions in 2018 taught by two different educators. Survey questions covered many topics with inquiries focusing on comfort level with indications, contraindications and reading PC studies. These were rated using a 5-point Likert scale pre- and post-course. Other questions assessed the quality of the course materials, content, comfort with online training and plans for implementation into one's practice. At the end of the course, participants took a graded exam assessing their skill level reading PC. Statistical analysis was performed in SPSS 25.0. Results: 29 physicians participated in the training. The average age of participants was 52.3±13.1 years with an average of 20.1 ± 14.1 years in practice prior to the course. When comparing pre- with postcourse evaluations, there were significant increases in comfort levels with understanding indications (median: 1.0 pre- vs. 4.0 post-course, p< 0.001), contraindications (median: 4.0 pre- vs. 5.0 post-course, p<0.001) and reading (median: 4.0 pre- to 5.0 post-course, p<0.001) PC studies. The mean score of comfort level reading PC prior to the training was 1.5 vs. 4.2 after course completion, a marked improvement in comfort level. At the end of training, 95.4% of trainees who completed the assessment correctly identified all pathology. Conclusion: An in-person, live training course for PC is an effective method for clinicians to become proficient with PC. More live-courses might be beneficial for greater understanding and usage of PC, to implement this technology into our clinical arsenal of tools designed to help patients with incomplete colonoscopic exams and lower gastrointestinal bleeding of undetermined etiology.