In this paper the statistical indicators concerning non-fatal and fatal accidents at work in the European Union (EU-28) and in the Republic of North Macedonia from 2012 to 2018 in construction sector were presented. The performed statistical analysis shows that the number of non-fatal and fatal accidents at work in EU-28 in 2018 was decreased in comparison with 2012. In the Republic of North Macedonia in 2018 there was an increase in the number of non- fatal and fatal accidents at work in construction sector in comparison to the number of accidents at work in 2012. Nevertheless, in the Republic North of Macedonia the value of incidence rate for fatal accidents at work in construction sector in 2018 is much lower compared to the average value in EU-28.