Background and Aims Eosinophilia may be associated with parasitic infection. To our knowledge the predictive value of eosinophilia has not been determined in internationally adopted children (IAC). Methods Eosinophilia definition: absolute count ≥ 450/µl. Eosinophil counts were available in 285/314 IAC seen between 01/01/2008 and 31/03/20012. Feces and serological examinations for Strongyloides and Schistosoma were done in all children. We calculated the positive predictive value, negative predictive value and likelihood ratios of eosinophilia ≥ 450/µl for all parasites, solely pathogenic and solely tissue invading parasites in all 285 and 197 Ethiopian children. Results Abstract 930 Table 1All 285 children Any parasites No parasites Pathogenic parasites No pathogenic parasites Tissue invading parasites No tissue invading parasites Eosinophils ≥ 450 65 13 60 18 37 41 Eosinophils < 450 129 78 99 108 40 167 PPV 83% 77% 47% NPV 38% 52% 81% LR+ 2.35 2.64 2.44 LR- 0.78 0.73 0.65 Abstract 930 Table 2197 Ethiopian children Any parasites No parasites Pathogenic parasites No pathogenic parasites Tissue invading parasites No tissue invading parasites Eosinophils ≥ 450 59 9 54 14 33 35 Eosinophils < 450 92 37 72 57 30 99 PPV 87% 79% 49% NPV 29% 44% 77% LR+ 2 2.17 2.01 LR- 0.76 0.71 0.64 Conclusion In this population the predictive value of eosinophilia is weak for parasitic infection.