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Blaizot, Muriel Giansily; Biron‐Andreani, Christine; Aguilar‐Martinez, Patricia; De Moeloose, Philippe; Briquel, Marie‐Elisabeth; Goudemand, Jenny; Stieltjes, Nathalie; Barrot, Claire; Chambost, Herve; Durin, Anne; Gay, Valerie; Peynet, Jocelyne; Pouymayou, Katia; Schved, Jean‐François
British journal of haematology, April 2002, Letnik: 117, Številka: 1Journal Article
Inherited factor VII (FVII) deficiency is a rare autosomal disorder characterized by a weak relationship between FVII activity (FVII:C) and operative bleeding risk. We report a retrospective study of 17 patients with a FVII:C below 0·1 IU/ml, in whom surgery was performed without any replacement therapy. Clinical and biological data were analysed to establish predictive criteria for bleeding tendency. We found that systematic preoperative replacement therapy may not be necessary for ‘minor’ surgical procedures, for patients suffering from inherited FVII deficiency, unless the clinical history includes severe haemorrhagic symptoms such as haemarthrosis, severe haematomas (even of soft tissue) or abundant epistaxis.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Vir: Osebne bibliografije
in: SICRIS
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