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Matilainen, Maarit, M.B; Peuhkurinen, Sini, M.Sc; Laitinen, Paivi, Ph.D; Jarvela, Ilkka, M.D; Morin-Papunen, Laure, M.D; Ryynanen, Marku, M.D., Ph.D
Fertility and sterility, 2011, 2011-Jan, 2011-01-00, 20110101, Letnik: 95, Številka: 1Journal Article
The maternal serum levels of pregnancy-associated plasma protein-A (PAPP-A) were reduced in hormonally stimulated pregnancies in the in vitro fertilization and intracytoplasmic sperm injection groups (N = 176; PAPP-A: 0.82) and in the entire assisted reproduction group (N = 282; PAPP-A: 0.83) as compared with controls (N = 24,783; PAPP-A: 0.94). However, the false-positive rate of first-trimester combined screenings was not statistically significantly increased in assisted reproduction pregnancies after adjustment for maternal age.
