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  • Human STAT5b mutation cause...
    Vargas-Hernández, Alexander; Witalisz-Siepracka, Agnieszka; Prchal-Murphy, Michaela; Klein, Klara; Mahapatra, Sanjana; Al-Herz, Waleed; Mace, Emily M.; Carisey, Alexandre F.; Orange, Jordan S; Sexl, Veronika; Forbes, Lisa R.

    Journal of allergy and clinical immunology, 10/2019, Letnik: 145, Številka: 1
    Journal Article

    In humans, the absence of STAT5b mimics the abrogated NK cell terminal maturation observed in Stat5b −/− mice. NK cells from STAT5b patients had a decreased cytolytic function and impaired convergence of lytic granules to the microtubule-organizing center.