In flagrant violation of international law, Russia has invaded Ukraine. It invokes a right to intervene on humanitarian and security grounds despite the necessary pre-conditions, including UN Security Council endorsement, being absent. In Myanmar, the February 2021 military coup has ushered in a new era of serious repression of citizens, violent conflict and human rights violations. ASEAN's 2021 five-point consensus to end the violence and promote conciliation has been largely ignored. These are but two of a number of current global threats which defy unilateral resolution and demand multilateral responses. Others are the looming disasters provoked by climate change; the ongoing Covid pandemic; conflict and the threat of conflict from Syria and Yemen to the South China Sea; the return of repressive Taliban rule in Afghanistan; ferocious civil war in Ethiopia; historically high refugee displacement; and mass migratory movements.