Background The occurrence and development of osteoporosis experience a long process, therefore, attention should be paid to bone health throughout the whole life cycle of human, early prevention and treatment of osteoporosis is of positive significance. There is a relative lack or insufficiency of research on TCM symptom assessment in the high risk population of osteoporosis in Ling-nan region.Objective To conduct expert questionnaire analysis on the assessment of TCM symptoms in high risk population of osteoporosis in Ling-nan region and form expert consensus opinions.Methods Based on the previous literature review and the first round of "Questionnaire for TCM symptom assessment in high risk population of osteoporosis in Ling-nan region", the Delphi method was adopted to optimize the second round of expert questionnaire from October 2021 to September 2022, in combination with the expert opinions of the first academic conference of Ling-nan bone and joint disease in December 2021 and the expert group of Guang