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Usefulness of follicular fluid estradiol and progesterone concentration measurement in predicting outcome of IVF/ICSI natural cycles = Uporabnost merjenja koncentracije estradiola in progesterona v folikularni tekočini pri napovedovanju izida IVF/ICSI postopka v naravnem ciklusuGavrić-Lovrec, Vida ...Namen: Namen raziskave je bil ugotoviti ali lahko na osnovi koncentracije estradiola (E2) in progesterona (P) ter njunega razmerja v folikularni tekočini predvidimo izhod IVF/ICSI postopkov v ... naravnih ciklusih. Metode: V raziskavo smo vključili 91 žensk, pri katerih smo naredili 150 postopkov IVF/ICSI (78 IVF in 72 ICSI) v naravnem ciklusu. Folikularno tekočino smo zbrali pri aspiraciji foliklov. S t-testom testom smo primerjali koncentracije E2 in P v folikularni tekočini (FT) in njuno razmerje (FT P/FT E2) med ciklusi z uspešno (z jajčno celico) in ciklusi z neuspešno (brez jajčne celice) aspiracijo foliklov, med ciklusi z oploditvijo in ciklusi brez oploditve jajčne celice in med ciklusi z zanositvijo in ciklusi brez zanositve. Rezultati: Jajčno celico smo dobili v 123 (86,7 %) ciklusih, do oploditve je prišlo v 84 (68,3 %) in zanositve v 21 ciklusih (delež zanositve na ciklus 14,0 %). Povprečna koncentracija E2 v FT je bila 3530 +/- 1339 nmol/L, povprečna koncentracija P v FT 20649 +/- 9489 nmol/L in povprečna vrednost razmerja FT P/FT E2 7,18 +/- 6,42. Povprečne vrednost E2, P in njunega razmerja v FT se niso statistično pomembno razlikovale med ciklusi z uspešno in neuspešno aspiracijo jajčnih foliklov, med ciklusi z in brez oploditve jajčne celice in med ciklusi z in brez zanositve. Zaključek: Na osnovi vrednosti E2 in P v folikularni tekočini ne moremo predvideti uspešnosti postopkov IVF/ICSI v naravnem ciklusu.Source: Acta medico-biotechnica : AMB. - ISSN 1855-5640 (Vol. 5, [no.] 1, 2012, str. 39-45)Type of material - article, component part ; adult, seriousPublish date - 2012Language - englishCOBISS.SI-ID - 4331327
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Gavrić-Lovrec, Vida | 08397 |
Vlaisavljević, Veljko | 08996 |
Kovačič, Borut | 11040 |
Gorenjak, Maksimiljan | 07616 |
Reljič, Milan | 15711 |
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