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Evaluation of the Amplicor HCV test: experiences after 1 year of routine use in a diagnostic laboratorySeme, Katja, 1966- ; Poljak, Mario, 1965-To evaluate the usefulness of a standardized commercial amplication assay for detection of hepatitis C virus (HCV) RNA, amplicor HCV test (Rhoche), a total of 1,204 serum samples from 888 patients ... was examined. Seven out of 443 anti-HCV-negative samples, 638 out of 729 anti-HCV-positive samples and four out 32 anti-HCV-indeterminate samples tested HCV RNA positive by amplicor in initial testing. One false-negative and five false-positive amplicor result were found in initial testing, giving an overall sensitivity and specificity of the amplicor HCV test 99,8% and 99.1%, respectively. Our study confirmed that the amplicor HCV test is a practical, rapid, sensitive and specific assay for detection of HCV RNA. However, the results must be interpreted with some caution and with the patient's anti-HCV status and clinical data in mind.Source: Infection. - ISSN 0300-8126 (Let. 24, št. 2, 1996, str. 140-143)Type of material - article, component partPublish date - 1996Language - englishCOBISS.SI-ID - 5016793
Author
Seme, Katja, 1966- |
Poljak, Mario, 1965-
Topics
Hepatitis c |
Diagnosis |
Hepatitis c viruses |
Polymerase chain reaction |
Rna
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Seme, Katja, 1966- | 14504 |
Poljak, Mario, 1965- | 11622 |
Source: Personal bibliographies
and: SICRIS
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