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Novosti pri zdravljenju z zaviralci SGLT2 in agonisti receptorjev GLP-1 = Novelties in the treatment of SGLT2 inhibitors and GLP-1 receptor agonistsMartinc, BoštjanSladkorna bolezen tipa 2 je ena izmed najpogostejših kroničnih nenalezljivih bolezni. Zaradi svoje pogostosti, zahtevne in kompleksne obravnave ter težkih posledic predstavlja velik zdravstveni, ... socialni in ekonomski problem. Poglavitni vzrok obolevnosti in visoke umrljivosti bolnikov s sladkorno boleznijo tipa 2 predstavljajo srčno-žilne bolezni, na katere poleg klasičnih dejavnikov tveganja, kot so arterijska hipertenzija, debelost, dislipidemija, albuminurija in kajenje, neodvisno vplivata tudi s sladkorno boleznijo povezano srčno popuščanje in diabetična ledvična bolezen. Z multifaktorskim pristopom zdravljenja ter vpeljavo novih učinkovin iz razredov receptorskih agonistov GLP-1 ter zaviralcev SGLT2 se je obravnava sladkorne bolezni pomembno izboljšala. Posledično sta se znatno zmanjšali srčno-žilna obolevnost in umrljivost, hkrati pa se je izboljšala z zdravjem povezana kakovost življenja. Uvedba receptorskih agonistov GLP-1 in zaviralcev SGLT2 predstavlja nov mejnik, ne samo pri obvladovanju sladkorne bolezni, temveč tudi v zmanjšanju pojavnosti hospitalizacij zaradi poslabšanja srčnega popuščanja ter preprečevanju razvoja in napredovanja kronične ledvične bolezni.Source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 73, št. 2, maj 2022, str. 115-127)Type of material - article, component part ; adult, seriousPublish date - 2022Language - slovenianCOBISS.SI-ID - 140694531
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source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 73, št. 2, maj 2022, str. 115-127)
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Martinc, Boštjan | ![]() |
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