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Equinatoxin II-induced lysis of the cultured endothelial cell line ECV-304Bunc, Matjaž ...Equinatoxin II (EqT II) is a pore-forming actinoporin. Its lethality in rat tissue is due to cardio-respiratory effects. The toxin contracts the vascular smooth muscle only in the presence of intact ... endothelium. In our study, its effects on the endothelial cell culture ECV-304 were tested: The EqT II effects were dose-dependent and were influenced by calcium ions and sucrose. The obtained results support the conclusion that calcium ions are the intracellular messengers of the EqT II effects on the isolated endothelial cells.Source: Cellular & molecular biology letters : an international journal : cellular membranes, cytoskeleton, nuclear architecture, gene expression, biomolecular interactions, biotechnology. - ISSN 1425-8153 (Vol. 7, no. 2, 2002, str. 351-353)Type of material - article, component partPublish date - 2002Language - englishCOBISS.SI-ID - 15259865
Author
Bunc, Matjaž |
Rozman, Janez, 1956- |
Starc, Radovan |
Maček, Peter |
Šuput, Dušan
Topics
Cnidarian venoms |
Endothelium, vascular |
Drug effects |
Calcium |
Sucrose |
Cell line |
Microscopy, confocal |
Endotelij žilni |
Kalcij |
Ožigalkarji, strupi |
Saharoza |
Celična linija |
Mikroskopija konfokalna |
ožigalkarji |
strupi |
endotelij
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Bunc, Matjaž | 15667 |
Rozman, Janez, 1956- | 04293 |
Starc, Radovan | 02020 |
Maček, Peter | 06994 |
Šuput, Dušan | 07002 |
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