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Zdravljenje težke oblike malarije = Treatment of severe malariaJereb, Matjaž, 1961- ...Background. Malaria represents a medical emergency as it may rapidly progress to complication and death without a prompt and apppropriate treatment. Severe malaria is almost exclusively caused by ... Plasmodium falciparum. The incidence of imported malaria in developed countries has been increasing and the case fatality rate remains high despite progress in intensive care management and antimalarial treatment. Clinical deterioration usually appears 3 to 7 days after onset of fever. Complications involve the nervous, respiratory, renal and/or hematopoietic system. Acidosis and hypoglycemia are also common. Conclusions. Intravenous quinine is the most widely used drug in the initial treatment of severe falciparum malaria whereas artemisinin derivatives are currently in developed countries recommended only for quinine-resistant cases.As soon as the patient is clinically stable and can swallow, oral treatment should be given. The intravascular volume should be maintained at the lowest level sufficient for adequate systemic perfusion to prevent development of acute respiratory distress syndrome. Renal replacement therapy in acute renal failure should be initiated early. Exchange blood transfusion has been suggested for the treatment of patients with severe malaria and hyperparasitemia. For the early diagnosis, it is of paramount importance to consider malaria in every febrile patient with a history of travel within an endemic area for the last years.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 73, št. 3, mar. 2004, str. 131-137)Type of material - article, component partPublish date - 2004Language - slovenianCOBISS.SI-ID - 17563609
Author
Jereb, Matjaž, 1961- |
Bombek, Maja |
Kšela, Juš |
Kobe, Jasna Modrica |
Muzlovič, Igor |
Trampuž, Andrej
Topics
Malaria, Falciparum |
Diagnosis |
Therapy |
Plasmodium Falciparum |
Antimalarials |
Intensive Care |
Quinine |
Quinidine |
Chloroquine |
Hemodialysis |
Exchange Transfusion, Whole Blood |
Antimalariki |
Intenzivna oskrba |
Malarija falciparna |
Plasmodium falciparum |
Izmenjalna transfuzija celotne krvi |
Kinidin |
Kinin |
Klorokin |
malarija |
zdravljenje
source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 73, št. 3, mar. 2004, str. 131-137)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Jereb, Matjaž, 1961- | 13300 |
Bombek, Maja | |
Kšela, Juš | 29766 |
Kobe, Jasna Modrica | 09987 |
Muzlovič, Igor | 11498 |
Trampuž, Andrej | 19772 |
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