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Synthesis and cholinesterase inhibitory activity of selected indole-based compounds [Elektronski vir]Gršič, Marija ...Synthesis and anticholinesterase activity of 18 previously unpublished indole- and tryptophan-derived compounds are disclosed. These compounds containing an indole structural unit exhibit selective ... submicromolar inhibition of human butyrylcholinesterase (hBChE). The structures of the newly synthesized compounds were confirmed by ▫$^1H$▫ and ▫$^{13}NMR$▫1H, IR spectroscopy, and high-resolution mass spectrometry.Source: Acta chimica slovenica [Elektronski vir]. - ISSN 1580-3155 (Vol. 70, no. 4, 2023, str. 545-559)Type of material - e-article ; adult, seriousPublish date - 2023Language - englishCOBISS.SI-ID - 179806979
Author
Gršič, Marija |
Meden, Anže |
Knez, Damijan, farmacevt |
Jukič, Marko |
Svete, Jurij |
Gobec, Stanislav, 1970- |
Grošelj, Uroš
Topics
indole derivatives |
tryptophan derivatives |
amidations |
cholinesterase (ChE) inhibitors |
1,1’-Carbonyldiimidazole (CDI) |
rearrangements |
catalytic hydrogenation |
derivati indola |
derivati triptofana |
amidacije |
zaviralci holinesteraze (ChE) |
1,1’-karbonildiim-idazol (CDI) |
prerazporeditve |
katalitsko hidrogeniranje
Author | Gršič, Marija ... |
Title | Synthesis and cholinesterase inhibitory activity of selected indole-based compounds [Elektronski vir] |
Publication date | |
COBISS.SI-ID | 179806979 |
Publication version in repository | Publisher's version |
Publication licence | Creative Commons Attribution 4.0 International |
Embargo | Immediate publication for public |
Project(s) from which the publication was funded
Title | Acronym | Project ID | Funder |
---|---|---|---|
Napredna organska sinteza in kataliza | P1-0179-2020 |
Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije |
|
Farmacevtska kemija: načrtovanje, sinteza in vrednotenje učinkovin | P1-0208-2022 |
Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije |
|
Razvoj multifunkcionalnih učinkovin za zdravljenje Alzheimerjeve bolezni | L1-8157-2017 |
Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije |
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Link |
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https://acsi-journal.eu/index.php/ACSi/article/view/8460/10029 |
https://repozitorij.uni-lj.si/IzpisGradiva.php?id=153470 |
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Gršič, Marija | |
Meden, Anže | 53584 |
Knez, Damijan, farmacevt | 36438 |
Jukič, Marko | 32587 |
Svete, Jurij | 08284 |
Gobec, Stanislav, 1970- | 15284 |
Grošelj, Uroš | 22602 |
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