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  • Do haemostasis activation markers that predict cardiovascular disease exist?
    Stegnar, Mojca ; Vene, Nina ; Božič, Mojca, 1970-
    Recognition of the central role of thrombosis in the pathogenesis of cardiovascular disease has prompted growing interest in the association of haemostatic variables with cardiovascular disease. In ... investigating the predictive value of haemostasis markers, a promising type of measurement is that of the activation products of coagulation and fibrinolysis: prothrombin fragment 1+2 (F1+2), fibrinopeptide A (FPA), soluble fibrin, thrombin-antithrombin (TAT), plasmin-antiplasmin (PAP) complexes and D-dimer. D-dimer was most extensively studied and there is substantial evidence that D-dimer is a strong, consistent predictor of cardiovascular events in the general population and in patients with cardiovascular disease. Data on other markers are considerably less abundant and more controversial. The prognostic value of these markers remains to be fully defined in future epidemiological and clinical studies.
    Source: Pathophysiology of haemostasis and thrombosis. - ISSN 1424-8832 (no. 5/6, Vol. 33, sep.-dec. 2003/2004, str. 302-308)
    Type of material - conference contribution
    Publish date - 2004
    Language - english
    COBISS.SI-ID - 18631385

source: Pathophysiology of haemostasis and thrombosis. - ISSN 1424-8832 (no. 5/6, Vol. 33, sep.-dec. 2003/2004, str. 302-308)

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