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HIV - immunost in razvoj cepiv = HIV - immunity and vaccine developmentIhan, AlojzOkužba s HIV vzbudi protitelesni in citotoksični imunski odziv proti virusu. HIV se zaradi izjemne prilagodljivosti in spremenljivosti uspešno izmika učinkoviti imunski zaščiti. Za razvoj bolezni je ... verjetno odločilen imunski odziv neposredno po virusni okužbi. Močan in proti ustreznim virusnim molekulam usmerjen začetni imunski odziv omogoča dober dolgoročni nadzor nad virusom. Če je začetni imunski odziv neu- strezno usmerjen se HIV verjetno tako namnoži, da dolgoročni nadzor okužbe ni več mogoč. Iz tega razmisleka izhajajo tudi najnovejše strategije pri razvoju cepiv proti aidsu - cepivo najbi usmerilo imunsko reakcijo proti izbranim virusnim antigenom. S tem bi virus naletel na učinkovito usmerjen in močan imunski odziv, ki bi omogočal dolgoročen nadzor virusa in s tem preprečeval razvoj aidsa.Source: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 36, [št.] 3, sep. 1997, str. 329-335)Type of material - article, component partPublish date - 1997Language - slovenianCOBISS.SI-ID - 7584473
source: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 36, [št.] 3, sep. 1997, str. 329-335)
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Ihan, Alojz | 10337 |
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