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The risk of second primary tumors in head and neck cancer : a systematic reviewCoca-Pelaz, Andrés ...BACKGROUND: Second primary tumors (SPTs) are a common cause of reduced life expectancy in patients treated for head and neck cancer (HNC). This phenomenon forms an area to be addressed during ... posttreatment follow-up. METHODS: We conducted a systematic review of literature following PRISMA guidelines, from 1979 to 2019, to investigate incidence of SPTs, synchronous, and metachronous, in HNC population. RESULTS: Our review includes data of 456%130 patients from 61 articles. With a minimum follow-up of 22%months, mean incidence of SPTs was 13.2% (95% CI: 11.56-14.84): 5.3% (95% CI: 4.24-6.36) for synchronous SPTs and 9.4% (95% CI: 7.9-10.9) for metachronous SPTs. The most frequent site for SPTs was head and neck area, followed by the lungs and esophagus. CONCLUSION: Although with wide variations between studies, the rate of SPTs in HNC patients is high. Given the impact in the prognosis, we must develop strategies for the early diagnosis of SPTs.Source: Head and neck. - ISSN 1043-3074 (Vol. 42, no. 3, mar. 2020, str. 456-466)Type of material - article, component partPublish date - 2020Language - englishCOBISS.SI-ID - 3476347
Author
Coca-Pelaz, Andrés |
Rodrigo, Juan Pablo |
Suárez, Carlos, zdravnik |
Nixon, Iain J. |
Mäkitie, Antti A. |
Sanabria, Alvaro |
Quer, Miquel |
Strojan, Primož |
Bradford, Carol R. |
Kowalski, Luiz P.
Topics
rak glave in vratu |
metakroonus |
sekundarni tumor |
ploščatocelični rak |
head and neck cancer |
metachronous |
second primary tumor |
squamous cell carcinoma
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Coca-Pelaz, Andrés | |
Rodrigo, Juan Pablo | |
Suárez, Carlos, zdravnik | |
Nixon, Iain J. | |
Mäkitie, Antti A. | |
Sanabria, Alvaro | |
Quer, Miquel | |
Strojan, Primož | 14576 |
Bradford, Carol R. | |
Kowalski, Luiz P. |
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