We review lattice results related to pion, kaon, D- and B-meson physics with the aim of making them easily accessible to the particle-physics community. More specifically, we report on the ...determination of the light-quark masses, the form factor \f_+(0)\, arising in the semileptonic \K \rightarrow \pi \ transition at zero momentum transfer, as well as the decay constant ratio \f_K/f_\pi \ and its consequences for the CKM matrix elements \V_{us}\ and \V_{ud}\. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of \SU(2)_L\times SU(2)_R\ and \SU(3)_L\times SU(3)_R\ Chiral Perturbation Theory. We review the determination of the \B_K\ parameter of neutral kaon mixing as well as the additional four B parameters that arise in theories of physics beyond the Standard Model. The latter quantities are an addition compared to the previous review. For the heavy-quark sector, we provide results for \m_c\ and \m_b\ (also new compared to the previous review), as well as those for D- and B-meson-decay constants, form factors, and mixing parameters. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. Finally, we review the status of lattice determinations of the strong coupling constant \\alpha _s\.
To conduct a meta-analysis of resting-state functional magnetic resonance imaging (R-fMRI) studies in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and in adults with ...ADHD to assess spatial convergence of findings from available studies.
Based on a preregistered protocol in PROSPERO (CRD42019119553), a large set of databases were searched up to April 9, 2019, with no language or article type restrictions. Study authors were systematically contacted for additional unpublished information/data. Resting-state functional magnetic resonance imaging studies using seed-based connectivity (SBC) or any other method (non-SBC) reporting whole-brain results of group comparisons between participants with ADHD and typically developing controls were eligible. Voxelwise meta-analysis via activation likelihood estimation with cluster-level familywise error (voxel-level: p < .001; cluster-level: p < .05) was used.
Thirty studies (18 SBC and 12 non-SBC), comprising 1,978 participants (1,094 with ADHD; 884 controls) were retained. The meta-analysis focused on SBC studies found no significant spatial convergence of ADHD-related hyperconnectivity or hypoconnectivity across studies. This nonsignificant finding remained after integrating 12 non-SBC studies into the main analysis and in sensitivity analyses limited to studies including only children or only non–medication-naïve patients.
The lack of significant spatial convergence may be accounted for by heterogeneity in study participants, experimental procedures, and analytic flexibility as well as in ADHD pathophysiology. Alongside other neuroimaging meta-analyses in other psychiatric conditions, the present results should inform the conduct and publication of future neuroimaging studies of psychiatric disorders.
Volcanic eruptions are caused by the release of pressure that has accumulated due to hot volcanic fluids at depth. Here, we show that the extent of the regions affected by pressurized fluids can be ...imaged through the measurement of their response to transient stress perturbations. We used records of seismic noise from the Japanese Hi-net seismic network to measure the crustal seismic velocity changes below volcanic regions caused by the 2011 moment magnitude (Mw) 9.0 Tohoku-Oki earthquake. We interpret coseismic crustal seismic velocity reductions as related to the mechanical weakening of the pressurized crust by the dynamic stress associated with the seismic waves. We suggest, therefore, that mapping seismic velocity susceptibility to dynamic stress perturbations can be used for the imaging and characterization of volcanic systems.
FLAG Review 2019 Aoki, S; Aoki, Y; Bečirević, D ...
The European physical journal. C, Particles and fields,
02/2020, Volume:
80, Issue:
2
Journal Article
Peer reviewed
Open access
We review lattice results related to pion, kaon, D-meson, B-meson, and nucleon physics with the aim of making them easily accessible to the nuclear and particle physics communities. More ...specifically, we report on the determination of the light-quark masses, the form factor f+(0) arising in the semileptonic K→π transition at zero momentum transfer, as well as the decay constant ratio fK/fπ and its consequences for the CKM matrix elements Vus and Vud. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of SU(2)L×SU(2)R and SU(3)L×SU(3)R Chiral Perturbation Theory. We review the determination of the BK parameter of neutral kaon mixing as well as the additional four B parameters that arise in theories of physics beyond the Standard Model. For the heavy-quark sector, we provide results for mc and mb as well as those for D- and B-meson decay constants, form factors, and mixing parameters. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. We review the status of lattice determinations of the strong coupling constant αs. Finally, in this review we have added a new section reviewing results for nucleon matrix elements of the axial, scalar and tensor bilinears, both isovector and flavor diagonal.
We review lattice results related to pion, kaon,
D
- and
B
-meson physics with the aim of making them easily accessible to the particle-physics community. More specifically, we report on the ...determination of the light-quark masses, the form factor
f
+
(
0
)
, arising in the semileptonic
K
→
π
transition at zero momentum transfer, as well as the decay constant ratio
f
K
/
f
π
and its consequences for the CKM matrix elements
V
u
s
and
V
u
d
. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of
S
U
(
2
)
L
×
S
U
(
2
)
R
and
S
U
(
3
)
L
×
S
U
(
3
)
R
Chiral Perturbation Theory. We review the determination of the
B
K
parameter of neutral kaon mixing as well as the additional four
B
parameters that arise in theories of physics beyond the Standard Model. The latter quantities are an addition compared to the previous review. For the heavy-quark sector, we provide results for
m
c
and
m
b
(also new compared to the previous review), as well as those for
D
- and
B
-meson-decay constants, form factors, and mixing parameters. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. Finally, we review the status of lattice determinations of the strong coupling constant
α
s
.
We investigated the effects of silica(SiO2) and clay nanoparticles on the tensile properties of poly(vinyl alcohol) (PVA) hydrogels containing borax. Clay/PVA/borax hydrogels possessed comparatively ...high tensile strength even at low concentrations of clay, but the mechanical performance drastically became worse at high concentrations. On the contrary, the tensile strength of SiO2/PVA/borax hydrogels increased with increasing SiO2 concentrations under high elongation. In these hydrogels, multiple crosslinking such as physical interactions between clay and PVA, complexations between PVA (or SiO2) and borate, microcrystals of PVA produced a tough polymer network. Besides, the synergistic effects of clay and SiO2 nanoparticles on the mechanical performance of the PVA/borax hydrogels were confirmed, i.e., both extensibility and modulus were largely improved compared to clay/PVA/borax or SiO2/PVA/borax hydrogels. Synchrotron small-angle X-ray scattering analysis revealed that the addition of both clay and SiO2 nanoparticles suppressed inhomogeneities in the composite gel.
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•Clay/PVA/borax gels possessed high tensile strength at low clay concentrations.•SiO2/PVA/borax gels possessed high elongation even at high SiO2 concentrations.•The addition of SiO2 and clay to PVA/borax gels caused high elongation and strength.•Combined use of nanoparticles and borax was effective for production of tough polymer gels.
Summary Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections, and associated ...precancerous lesions in an event-triggered interim analysis of the phase III randomised, double-blind, controlled PApilloma TRIal against Cancer In young Adults (PATRICIA). We now assess the vaccine efficacy in the final event-driven analysis. Methods Women (15–25 years) were vaccinated at months 0, 1, and 6. Analyses were done in the according-to-protocol cohort for efficacy (ATP-E; vaccine, n=8093; control, n=8069), total vaccinated cohort (TVC, included all women receiving at least one vaccine dose, regardless of their baseline HPV status; represents the general population, including those who are sexually active; vaccine, n=9319; control, n=9325), and TVC-naive (no evidence of oncogenic HPV infection at baseline; represents women before sexual debut; vaccine, n=5822; control, n=5819). The primary endpoint was to assess vaccine efficacy against cervical intraepithelial neoplasia 2+ (CIN2+) that was associated with HPV-16 or HPV-18 in women who were seronegative at baseline, and DNA negative at baseline and month 6 for the corresponding type (ATP-E). This trial is registered with ClinicalTrials.gov , number NCT00122681. Findings Mean follow-up was 34·9 months (SD 6·4) after the third dose. Vaccine efficacy against CIN2+ associated with HPV-16/18 was 92·9% (96·1% CI 79·9–98·3) in the primary analysis and 98·1% (88·4–100) in an analysis in which probable causality to HPV type was assigned in lesions infected with multiple oncogenic types (ATP-E cohort). Vaccine efficacy against CIN2+ irrespective of HPV DNA in lesions was 30·4% (16·4–42·1) in the TVC and 70·2% (54·7–80·9) in the TVC-naive. Corresponding values against CIN3+ were 33·4% (9·1–51·5) in the TVC and 87·0% (54·9–97·7) in the TVC-naive. Vaccine efficacy against CIN2+ associated with 12 non-vaccine oncogenic types was 54·0% (34·0–68·4; ATP-E). Individual cross-protection against CIN2+ associated with HPV-31, HPV-33, and HPV-45 was seen in the TVC. Interpretation The HPV-16/18 AS04-adjuvanted vaccine showed high efficacy against CIN2+ associated with HPV-16/18 and non-vaccine oncogenic HPV types and substantial overall effect in cohorts that are relevant to universal mass vaccination and catch-up programmes. Funding GlaxoSmithKline Biologicals.
We investigate the axial U ( 1 ) anomaly of two-flavor QCD at temperatures 190–330 MeV. In order to preserve precise chiral symmetry on the lattice, we employ the Möbius domain-wall fermion action as ...well as overlap fermion action implemented with a stochastic reweighting technique. Compared to our previous studies, we reduce the lattice spacing to 0.07 fm, simulate larger multiple volumes to estimate finite size effect, and take more than four quark mass points, including one below physical point to investigate the chiral limit. We measure the topological susceptibility, axial U ( 1 ) susceptibility, and examine the degeneracy of U ( 1 ) partners in meson/baryon correlators. All the data above the critical temperature indicate that the axial U ( 1 ) violation is consistent with zero within statistical errors. The quark mass dependence suggests disappearance of the U ( 1 ) anomaly at a rate comparable to that of the S U ( 2 ) L × S U ( 2 ) R symmetry breaking.
FLAG Review 2019 Aoki, S.; Aoki, Y.; Bečirević, D. ...
The European physical journal. C, Particles and fields,
02/2020, Volume:
80, Issue:
2
Journal Article
Peer reviewed
Open access
We review lattice results related to pion, kaon,
D
-meson,
B
-meson, and nucleon physics with the aim of making them easily accessible to the nuclear and particle physics communities. More ...specifically, we report on the determination of the light-quark masses, the form factor
f
+
(
0
)
arising in the semileptonic
K
→
π
transition at zero momentum transfer, as well as the decay constant ratio
f
K
/
f
π
and its consequences for the CKM matrix elements
V
us
and
V
ud
. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of
S
U
(
2
)
L
×
S
U
(
2
)
R
and
S
U
(
3
)
L
×
S
U
(
3
)
R
Chiral Perturbation Theory. We review the determination of the
B
K
parameter of neutral kaon mixing as well as the additional four
B
parameters that arise in theories of physics beyond the Standard Model. For the heavy-quark sector, we provide results for
m
c
and
m
b
as well as those for
D
- and
B
-meson decay constants, form factors, and mixing parameters. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. We review the status of lattice determinations of the strong coupling constant
α
s
. Finally, in this review we have added a new section reviewing results for nucleon matrix elements of the axial, scalar and tensor bilinears, both isovector and flavor diagonal.
Quantum chromodynamics (QCD) is the theory of the strong interaction, explaining (for example) the binding of three almost massless quarks into a much heavier proton or neutron-and thus most of the ...mass of the visible Universe. The standard model of particle physics predicts a QCD-related transition that is relevant for the evolution of the early Universe. At low temperatures, the dominant degrees of freedom are colourless bound states of hadrons (such as protons and pions). However, QCD is asymptotically free, meaning that at high energies or temperatures the interaction gets weaker and weaker, causing hadrons to break up. This behaviour underlies the predicted cosmological transition between the low-temperature hadronic phase and a high-temperature quark-gluon plasma phase (for simplicity, we use the word 'phase' to characterize regions with different dominant degrees of freedom). Despite enormous theoretical effort, the nature of this finite-temperature QCD transition (that is, first-order, second-order or analytic crossover) remains ambiguous. Here we determine the nature of the QCD transition using computationally demanding lattice calculations for physical quark masses. Susceptibilities are extrapolated to vanishing lattice spacing for three physical volumes, the smallest and largest of which differ by a factor of five. This ensures that a true transition should result in a dramatic increase of the susceptibilities. No such behaviour is observed: our finite-size scaling analysis shows that the finite-temperature QCD transition in the hot early Universe was not a real phase transition, but an analytic crossover (involving a rapid change, as opposed to a jump, as the temperature varied). As such, it will be difficult to find experimental evidence of this transition from astronomical observations.
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