We explore observational and theoretical constraints on how galaxies might transition between the "star-forming main sequence" (SFMS) and varying "degrees of quiescence" out to \(z=3\). Our analysis ...is focused on galaxies with stellar mass \(M_*>10^{10}M_{\odot}\), and is enabled by GAMA and CANDELS observations, a semi-analytic model (SAM) of galaxy formation, and a cosmological hydrodynamical "zoom in" simulation with momentum-driven AGN feedback. In both the observations and the SAM, transition galaxies tend to have intermediate Sérsic indices, half-light radii, and surface stellar mass densities compared to star-forming and quiescent galaxies out to \(z=3\). We place an observational upper limit on the average population transition timescale as a function of redshift, finding that the average high-redshift galaxy is on a "fast track" for quenching whereas the average low-redshift galaxy is on a "slow track" for quenching. We qualitatively identify four physical origin scenarios for transition galaxies in the SAM: oscillations on the SFMS, slow quenching, fast quenching, and rejuvenation. Quenching timescales in both the SAM and the hydrodynamical simulation are not fast enough to reproduce the quiescent population that we observe at \(z\sim3\). In the SAM, we do not find a clear-cut morphological dependence of quenching timescales, but we do predict that the mean stellar ages, cold gas fractions, SMBH masses, and halo masses of transition galaxies tend to be intermediate relative to those of star-forming and quiescent galaxies at \(z<3\).
Two study chimpanzees were inoculated intravenously with approximately 1,000 chimpanzee infectious doses of hepatitis B virus (HBV), one with subtype adr and one with subtype ayw, each previously ...incubated with 0.1 ml of a murine monoclonal antibody (IgG 1(K) class) directed against a single epitope on hepatitis B surface antigen common to most or all HBV. Two control chimpanzees received identical doses of HBV not incubated with the murine anti-HBs. Neither study chimpanzee developed HBV infection during 12 months of follow-up as judged by normal serum aminotransferase activity, normal liver biopsies, and negative serological tests for HBV-associated antigens and antibodies. In contrast, both control chimpanzees became infected by HBV as evidenced by elevated serum aminotransferase activity, liver biopsy changes characteristic of viral hepatitis, and the appearance of hepatitis B surface antigen (HBsAg) in their sera. Both study chimpanzees were shown to be fully susceptible to infection with these same HBV inocula when challenged 15 months after the initial inoculations at a time when passively administered anti-HBs was no longer detectable. Prior to challenge with HBV, one of the two study chimpanzees received a second injection of the same volume of the murine monoclonal anti-HBs. The survival of this anti-HBs in serum was reduced from six weeks (after the initial injection) to approximately two weeks.
Health care payors and consumers have a growing interest in risk-adjusted provider profiles. Using chart-abstracted clinical data from the Cooperative Cardiovascular Project, we ranked 28 hospitals ...performing bypass surgery in Alabama and Iowa by their risk-adjusted surgical mortality rates using three published risk-adjustment methodologies: Parsonnet (PI, O’Connor (a) and Hannan (H). In total. 3653 bypass surgery cases performed from 6/92 to 3/93 were reviewed (mean 130 cases/hospital). The discriminatory abilities of each method for predicting surgical mortality were quite similar (area under ROC curves 0.72–0.75). Below, we display the risk-adjusted hospital rankings (comparing observed with expected mortality) by these three riskadjustment techniques: Display omitted
In terms of hospital rankings, there was generally close correlation between any two of the methods (Spearman's R=0.87,0.88, and 0.93, comparing P-O, P-H, and H-O). Rankings for an individual hospital varied, however, an average of ±3.3 ranks (range 0–12 ranks) depending on which riskadjustment methodology was used.
In general. published methods of risk-adjustment for bypass surgery accurately identify institutions with low, moderate and high adjusted mortality outcomes. The precise ranking of an individual hospital. however, may vary depending on the risk adjustment method applied.
The present study investigated smoking prevalence, smoking motives, demographic variables and psychological symptoms in 124 help‐seeking, male Vietnam combat veterans with post‐traumatic stress ...disorder (PTSD). A high percentage of these veterans smoked (60%). Vietnam veterans with PTSD who smoked were more likely than those who did not smoke to report higher levels of PTSD symptoms, depression and trait anxiety. Increased depression was associated with increased automatic smoking. Smokers reported a high frequency of smoking in response to military memories. Implications for smoking interventions, cessation, and relapse prevention efforts are discussed.
1nthusiastic teachers and administrators who participated in Cummins Engine Foundation Writing Project seminars on writing across the curriculum have influenced the teaching of writing in their ...schools. References included.
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