In this paper, we develop a set of research hypotheses concerning the effects of six groups of factors on firms' behavior during the 2008 global economic crisis with respect to ICT investment: three ...groups of internal factors (overall firm resource endowment, ICT-related resource endowment, ICT-related capabilities) and three groups of factors (competition, liquidity problems, macroeconomic conditions concerning demand). These research hypotheses are tested using data from Greek firms for the economic crisis period 2009-2014.
A series of high affinity CRF receptor ligands with an imidazo4,5-
bpyridine core is described. Individual analogues were synthesized and tested in a rat CRF receptor binding assay. The best ...compounds were further tested in the dog N-in-1 pharmacokinetic model to assess plasma levels at 1
mg/kg (po) and in the rat situational anxiety model to assess anxiolytic efficacy at 3
mg/kg (po). The structure–activity relationships for good receptor binding affinity are described herein.
A series of high affinity CRF receptor ligands with an imidazo4,5-
bpyridine core is described. Analogues were synthesized and tested in a rat CRF receptor binding assay. The best compounds were tested in the dog N-in-1 pharmacokinetic at 1
mg/kg (po) and in the rat situational anxiety model at 3
mg/kg (po).
A series of high affinity CRF receptor ligands with an imidazo4,5-
cpyridine core is described. Individual analogues were synthesized and tested in vitro in rat brain receptors to determine binding ...affinity. The best compound was further tested in the dog N-in-1 pharmacokinetic model to assess oral bioavailability at 1 mg/kg po.
A series of high affinity CRF receptor ligands with an imidazo4,5-
cpyridine core is described. Individual analogues were synthesized and tested in vitro in rat brain receptors to determine binding affinity. The best compound was tested in the dog N-in-1 pharmacokinetic model at 1 mg/kg po.
Platination of 6-phenylimidazo2,1-bthiazole at the imidazole N atom to give chloro(ethylenediamine)(6-phenylimidazo2,1-b thiazole)platinum(II) nitrate, PtCl-(C2H8N2)(C11H8N2S)NO3, is accompanied by a ...rotation of 49.3 (8) degrees of the phenyl ring and a loss of extended conjugation in the normally planar 6-phenylimidazo2,1-bthiazole molecule.
![Imidazo[4,5- b]pyridines as...](http://api.summon.serialssolutions.com/2.0.0/image/issn/XR4PS5YY4K/0960-894X/small "Imidazo[4,5- b]pyridines as corticotropin releasing factor receptor ligands")
