Tropical forests face increasing climate risk
, yet our ability to predict their response to climate change is limited by poor understanding of their resistance to water stress. Although xylem ...embolism resistance thresholds (for example, Formula: see text
) and hydraulic safety margins (for example, HSM
) are important predictors of drought-induced mortality risk
, little is known about how these vary across Earth's largest tropical forest. Here, we present a pan-Amazon, fully standardized hydraulic traits dataset and use it to assess regional variation in drought sensitivity and hydraulic trait ability to predict species distributions and long-term forest biomass accumulation. Parameters Formula: see text
and HSM
vary markedly across the Amazon and are related to average long-term rainfall characteristics. Both Formula: see text
and HSM
influence the biogeographical distribution of Amazon tree species. However, HSM
was the only significant predictor of observed decadal-scale changes in forest biomass. Old-growth forests with wide HSM
are gaining more biomass than are low HSM
forests. We propose that this may be associated with a growth-mortality trade-off whereby trees in forests consisting of fast-growing species take greater hydraulic risks and face greater mortality risk. Moreover, in regions of more pronounced climatic change, we find evidence that forests are losing biomass, suggesting that species in these regions may be operating beyond their hydraulic limits. Continued climate change is likely to further reduce HSM
in the Amazon
, with strong implications for the Amazon carbon sink.
Inflammatory bowel disease (IBD) are chronic entities characterized by local and systemic inflammation and may be associated with thrombosis. The aim of this study was to identify the prevalence of ...thromboembolic events (TEE) in hospitalized IBD patients and identify risk factors for their occurrence.
This retrospective, single-center study included patients treated at a Brazilian IBD referral unit between 2004 and 2014. Patients hospitalized for more than 48 hours due to active IBD and who did not receive prophylaxis for TEE during hospitalization were included. Patients were allocated to 2 groups: those with TEE up to 30 days or at the time of hospitalization (TEE-group) and patients without TEE (control-group). Clinical and laboratory characteristics were evaluated.
Of 53 patients evaluated, 69,8% with Crohn's disease (CD) and 30.2% with ulcerative colitis (UC). The prevalence of TEE 30 days before or during hospitalization was 15.1%, with 10.8% in CD and 25% in UC. In the TEE group, mean serum albumin was 2.06 g/dL versus 3.30 g/dL in the control group. Patients with albumin levels below 2.95 g/dL (43.18%) had a higher risk of developing TEE (relative risk, 1.72; 95% confidence interval, 1.17-2.53) (P<0.001).
Albumin levels were significantly lower in patients with TEE, and hypoalbuminemia was considered a risk factor for the development of TEE in this population.
As dimensões matemática e pedagógica do conhecimento do professor são consideradas especializadas, e pretendese descrever o conteúdo do conhecimento revelado por participantes de um processo ...formativo com foco nos tópicos de Medida. Considerando o Mathematics Teacher’s Specialised Knowledge (MTSK), explora-se e descreve-se o conteúdo do conhecimento revelado por um grupo de professores ao resolverem uma Tarefa para a Formação, implementada em um curso para professores que atuam desde a Educação Infantil, no Brasil. Os resultados trazem um refinamento da categorização do conhecimento do professor, associada aos tópicos (KoT), ao considerar, de forma separada, o detalhamento do conteúdo desse conhecimento, relativamente a definições, propiedades e fundamentos. Além disso, no estudo, um conjunto de descritores de conhecimento evidenciam particularidades e especificidades dessa componente do conhecimento do professor, particularmente para os tópicos de Medida, possibilitando um tipo de mapeamento de elementos estruturais e estruturantes desse conhecimento.
To evaluate the histological and stage characteristics of cervical cancer in women under 25 years old, and to compare them with older women.
Cross-sectional study of cases from the Hospital Cancer ...Registry of São Paulo State/Brazil from 2000 to 2015. Variables were age, International Federation of Gynecology and Obstetrics stage and histological type. Prevalence ratio (PR) and its 95% confidence interval (CI) were calculated.
Out of 18,423 cervical cancer cases 204 (1.1%) were in women under 25 years old. The most frequent stage was stage I in women under 25 (36.2%) and between 25 and 34 (43.4%), and stage III in older women (31.8%). No statistically significant difference was observed in stages by age group. Squamous carcinomas were the most frequent in 73.5% of women under 25 and 78.5% of older women. In women under 25 the following histological types were more frequent: neuroendocrine carcinomas (PR=6.10, 95% CI=2.03-18.35), malignant germ cell tumors (PR=54.98, 95% CI=26.53-113.95), mesenchymal tumors (sarcomas) (PR=5.67, 95% CI=2.58-12.45) and hematopoietic/lymphoid tumors (PR=0.72, 95% CI=2.90-36.69).
In women under 25 years old cervical cancer was an uncommon diagnosis and in about one third occurred at early stage. Squamous carcinoma was the most frequent histological type regardless age, but rare histological types were more frequent in young women.
Este trabalho propõe discutir, a partir de excertos de postagens de dois perfis de professores circulados publicamente no aplicativo TikTok, o status de influenciador assumido por docentes que aderem ...à prática de produzir e compartilhar vídeos, com temática educacional ou não, nesse aplicativo. Adota-se a etnografia digital por metodologia, com a utilização de ferramentas de captura de tela para transformar trechos de vídeos em imagens estáticas, aqui representadas em figuras. A discussão encontra apoio na perspectiva dos Letramentos para abordar questões relacionadas ao lugar da educação e da docência na contemporaneidade, além de buscar apoio em estudos acerca de conceitos de cultura, de indústria cultural, da sociedade da comunicação em massa e da espetacularização, a fim de construir uma leitura qualitativa e interpretativa dos dados apresentados.
Universities are increasingly perceived as agents involved in regional development. It is now recognized that academic contributions to the socioeconomic environment go well beyond scientific ...investigation and teaching activities, and incorporate market-oriented initiatives to the academic mission. However, these effects are geographically bounded. Given these conditions, this article aims at addressing universities’ impacts upon output vectors of localized innovation ecosystems. Using data from cities and microregions in the state of Sao Paulo, Brazil observed throughout the period of 2002–2014, we address universities’ effects upon the local-level generation of patents and utility models, software production and emergence of knowledge-intensive entrepreneurship. Besides the scant available evidence on innovation ecosystems located outside developed economies, dealing with a developing country also means we are addressing an analytical unit in which universities play a critical role in terms of knowledge production and diffusion, a function of the weak competences of local firms.Findings support the hypothesis that major academic institutions lie at the heart of innovation ecosystems, but impacts are mostly local, happening more strongly at the level of cities. While the formation of human capital also contributes to innovative output, its impacts are of minor relevance as compared to higher education institutions that achieve excellence in research. This poses severe challenges for policymakers when targeting the formation and enhancement of initiatives to develop innovative ecosystems, particularly for peripheral areas. First, these regions are not likely to reap substantial benefits from proximity to successful hubs. Beyond that, creating local conditions is not as straightforward as sometimes announced in political discourse. In this regard, some fundamental vectors are not easily manipulated in the short-term and there seems to be fundamental importance attributed to long-term, evolutionary conditions. Such is the case for high-quality universities.
Composition and antimicrobial activity of essential oils from aromatic plants used in Brazil Sartoratto, Adilson(Universidade Estadual de Campinas Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas); Machado, Ana Lúcia M.(Universidade Estadual de Campinas Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas); Delarmelina, Camila(Universidade Estadual de Campinas Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas) ...
Brazilian journal of microbiology,
12/2004, Volume:
35, Issue:
4
Journal Article
Peer reviewed
Open access
Essential oils from aerial parts of Mentha piperita, M. spicata, Thymus vulgaris, Origanum vulgare, O. applii, Aloysia triphylla, Ocimum gratissimum, O. basilicum were obtained by steam destillation ...using a Clevenger-type system. These oils were screened for antibacterial and anti-Candida albicans activity using bioautographic method. Subsequently, minimal inhibitory concentration from oils was determined by microdilution method. Most essential oil studied were effective against Enterococcus faecium and Salmonella cholerasuis. Aloysia triphylla and O. basilicum presented moderate inhibition against Staphylococcus aureus while only A. tryphila and M. piperita were able to control the yeast Candida albicans. The oils were analyzed by GC and GC-MS techniques in order to determine the majoritary compounds.
Óleos essenciais foram obtidos a partir das partes aéreas de Mentha piperita, M. spicata, Thymus vulgaris, Origanum vulgare, O. applii, Aloysia triphylla, Ocimum gratissimum e O. basilicum através de arraste de vapor em sistema tipo Clevenger. Os óleos foram avaliados quanto à atividade antimicrobiana contra bactérias e contra a levedura Candida albicans pelo método de bioautografia. A concentração mínima inibitória dos óleos com atividade positiva foi em seguida determinada pelo método da microdiluição. De acordo com os resultados, a maioria dos óleos essenciais estudados foram efetivos contra Enterococcus faecium e Salmonella cholerasuis. A.triphylla e O. basilicum apresentaram inibição moderada contra Staphylococcus aureus enquanto apenas A. tryphila e M. piperita foram capazes de inibir a levedura Candida albicans. Os óleos foram analisados quimicamente por técnicas de CG e CG-EM de modo a determinar os compostos majoritários presentes.