•Simulated rice potential yields decreased in the near/far future in both study sites.•Adapted varieties with longer crop cycles provided a positive impact of CC on yield.•GCM and RCP greatly ...contributed to the uncertainty in future rice yield predictions.•The CC issue could represent an opportunity to increase potential rice yields in EU.
The future of global rice productions in top producing countries is undermined by the impact of climate change threatening food security in the near future. In those European Mediterranean areas where rice is cultivated, this peculiar cropping system plays a crucial role in terms of sociocultural and ecological issues, and the climate change impact is still scarcely investigated. In this study, we explored the future trends of potential rice yields in the region considering the multiple sources of uncertainty associated with climate and yield predictions. Two rice crop models (STICS and WARM) were calibrated using 20 field experiments carried out in two main European rice producing areas − i.e., the Italian Lomellina and the French Camargue. These models were then applied under a range of climate change scenarios in 2030 and 2070 time frames, considering projections from the combination of four General Circulation Models and two extreme Representative CO2 Concentration Pathways (RCP 2.6 and 8.5). We compared the simulated yield levels with no adaptation, and designed adaptation strategies based on the anticipation of sowing date and the adoption of varieties with longer crop cycle. Our results showed that with no adaptation yields would decrease on average by 8% in 2030 and 12% in 2070 in Camargue and Lomellina. Future simulated yields in the two areas were lower than in the baseline in 67% (Camargue) and 84% (Lomellina) of the cases. The implementation of both adaptation strategies proved to be effective in reversing the situation, leading to an average yield increase of 28% and 25% in 2030 and 2070, respectively. The associated probability of lower yields than in current conditions was 24% in the two sites. Despite the uncertainty in predictions, mainly related to site, GCM and RCP, our findings indicate that the European rice sector has the potential to enhance current production levels in a changing climate, if longer cycle varieties will be grown in Mediterranean rice areas.
•Air monitoring is a crucial tool to assess the environmental pollution from carbonyl compounds, especially formaldehyde.•The state of the art of sampling for airborne formaldehyde presents many ...passive and active solutions for several scenarios.•The analytical determination of formaldehyde with derivatizing agents: applications and their limits.•Direct reading instruments could give complementary information to conventional air monitoring for formaldehyde assessment.
Air monitoring is the quantitative-qualitative assessment of the extent of pollutants. It is performed to ensure compliance with legislation and to evaluate control measures and mitigation solutions. There are numerous approaches to measure airborne formaldehyde (FA), ranging from passive sampling techniques to remote sensing devices. Research of sampling procedures and analytical methods was performed in a scientific database and on the web to offer a scenario of the devices and techniques that can be used to assess FA exposure. Moreover, in the design of FA assessment, some crucial aspects were considered, such as standard atmosphere generation for devices calibration. This review summarizes the tools and basics used in FA air monitoring, useful to organize a functional monitoring strategy for assessment of FA concentration levels. An insight into the sampling and analysis of FA is provided. Recent advances in solid sorbent technology allow analysts to use these devices coupled to chromatographic instruments. A comparison of the strengths and weaknesses of analytical methods (gas-/liquid-chromatography coupled with mass spectrometry or UV detection, chromogenic, colorimetric, electrochemical determination) and sampling devices (impregnated papers, solid sorbents, liquid sorbents, bubblers, impingers, micro-impingers, denuder samplers, sealed bags, canisters) methods are illustrated. This survey found that a monitoring strategy should be planned considering the most appropriate methodology in terms of costs and practicability. Therefore, it is necessary to know the aspects that can make the chosen strategy suitable and valid for the exposure scenario under investigation.
Carbonyl compounds (CCs) are products present both as vapors and as condensed species adsorbed on the carbonaceous particle matter dispersed in the air of urban areas, due to vehicular traffic and ...human activities. Chronic exposure to CCs is a potential health risk given the toxicity of these chemicals. The present study reports on the measurement of the concentrations of 14 CCs in air as vapors and 2.5 µm fraction PM by the ENVINT GAS08/16 gas/aerosol sampler, a serial sampler that uses annular denuder, as sampling device. The 14 CCs were derivatized during sampling prior to gas-chromatographic separation and multiple detection by mass spectrometry, nitrogen-phosphorus thermionic, electron capture detection. Outdoor air multiple samples were collected in four locations in the urban area of Florence. The results evidenced that formaldehyde, acetaldehyde, and acetone were the more abundant CCs in the studied areas. The data collected was discussed considering the particle to vapor ratio of each CC found. The CCs pollution picture obtained was tentatively related to the nature and intensity of the traffic transiting by the sampling sites. This approach allowed to determine 14 CCs in both concentrated and diluted samples and is proposed as a tool for investigating outdoor and indoor pollution.
Crop models are reference tools that can be used to evaluate the performances of cropping systems under current and future agro-climatic scenarios. A recent trend is the adoption of multi-model ...ensembles, as crop model responses vary across pedoclimatic contexts. We present the web application MOBEDIS, aimed at investigating the causes of differences in crop models’ behaviour. MOBEDIS combines non-parametric statistical methods (Spearman correlation, Random Forest, Hierarchical clustering, Mantel statistics) to analyze and cluster crop models according to the relationship between final outputs (e.g., yield) and a set of intermediate outputs related to plant processes. We applied MOBEDIS in three case studies to (1) discuss its capability to facilitate the understanding of the behaviour of two crop models in a simulation experiment, and (2) prove its applicability for model ensemble studies. MOBEDIS is freely available and ready-to-use for understanding single model responses and identifying groups of crop models sharing similar behaviour.
•The application evaluates the relationship between crop models' final and intermediate outputs.•It can analyze single model responses and cluster a set of models.•Four non-parametric methods are used to avoid assumptions on variable distributions.•Three cases studies are presented to demonstrate the application capabilities.•Final results provide insights into differences between models' behaviours.
Radna izloženost rukovanju i primjeni antineoplastičnih lijekova (AD) jedan je od glavnih rizika u zdravstvenom sektoru. Kožna apsorpcija predstavlja primarni put izlaganju AD-ima. Osobna preventivna ...oprema, posebno medicinske rukavice, presudna je za zaštitu zdravlja radnika u radu s AD-ima; prema tome, kemikalije koje prodiru kroz zaštitne materijale bitan su aspekt za procjenu i razmatranje. Nekoliko studija o prožimanju kroz medicinske rukavice izvijestilo je da su vrijeme proboja i brzina prodiranja vrijednosti koje se moraju proučavati, primjećujući da su fizičko-kemijska svojstva lijekova, OZO materijali i debljina i temperatura ključne značajke za njihovu procjenu. U Europskoj uniji, standardizirano ispitivanje prožimanja nije obvezno za rukavice koje se koriste u manipulaciji ADs, za razliku od Sjedinjenih Država koje su predložile stroge zahtjeve u međunarodnom standardu D6978-05 Američkog društva za ispitivanje i materijale. Ovaj pregled pomogao bi identificirati glavne karakteristike najbolje zaštitne rukavice koju koriste zaposlenici često izloženi AD-ima: glavni aspekti uključeni u prožimanje, priopćeni u literaturi, navedeni su i raspravljeni.
The case concerns a 30-year-old woman in the 24th week of pregnancy presenting to the medical emergency room with fever and abdominal pain. Urine sediment microscopy revealed the presence of unknown ...needle-shaped crystals.
Crystals identification was performed by Fourier-Transform Infrared Spectroscopy coupled to Attenuated Total Reflectance (FTIR-ATR).
Amoxicillin crystals were verified with semiquantitative results of 87.7%.
Drug-induced crystalluria is a frequent finding in urine examination and it may be asymptomatic. FTIR spectroscopy is a rapid and specific tool in identification of crystals and could be useful supporting renal disease diagnosis and monitoring drug therapy.
Formaldehyde (FA) is a hazardous chemical, highly used in the anatomical pathology laboratories. The adverse health effects related to FA occupational exposure are generally related to long-term ...exposure, however the short-term exposure to peak concentrations are equally of high concern. The occupational monitoring commonly uses the 8h-Time Weight Average (TWA) metric to assess the exposure, but for those chemicals with acute effects, also the15min short-term exposure is strongly recommended. In this study, the occupational monitoring was carried out in an anatomical pathology laboratory with an in-continuous, instantaneous, and direct reading instrument for 65 work shifts (WS). In none of these, the FA European Union (EU) TWA occupational limit (620 g/m3) was exceeded. Differently, in 40 WS the EU Short Term Exposure Limit (STEL) (740 g/m3) was exceeded, even several times a WS. In sight of this, the 8h-TWA metric only could give poor information of the exposure scenario, involving peak emissions, then a 15min peak exposure assessment, via in continuous monitoring, could help managing the risk. In addition, using the inference equation, an Action Value (AV) of the 8h-TWA above which the 15min measurements are strongly recommended, equal to 23.1 g/m3, is suggested for FA.
Formaldehid (FA) je štetna kemikalija koja se vrlo često koristi u anatomskim patološkim laboratorijima. Loši utjecaji FA na zdravlje zaposlenika izloženih toj tvari općenito se povezuju s dugotrajnom izloženošću, iako je i kratkotrajna izloženost vršnim koncentracijama vrlo zabrinjavajuća. Za praćenje utjecaja obično se koristi mjerenje prosjeka 8 h vrijeme-težina (TWA) kako bi se procijenila izloženost, no za kemijske tvari koje imaju akutno djelovanje izrazito se preporučuje izračun utjecaja 15-minutne kratkotrajne izloženosti. Istraživanje praćenja utjecaja FA na radnom mjestu provedeno je u jednom patološkom laboratoriju pomoću kontinuiranog, trenutnog i izravnog očitanja mjernim intstrumentom u 65 radnih smjena (WS). Ni u jednoj EU granica TWA od 620 g/m3 nije bila viša. Nasuprot tome, u 40 radnih smjena prijeđena je EU granica kratkotrajne izloženosti (STEL) od 740 g/m3 i to više puta tijekom radnog vremena. Ako se ovo uzme u obzir, 8-satno TWA mjerenje daje samo šture podatke o scenariju izloženosti vršnim emisijama i o 15-minutnim procjenama najviše izloženosti, dok bi kontinuirano praćenje više pomoglo upravljanju rizikom. Uz to, preporuka za FA jest korištenje inferencijalne jednadžbe Akcijska vrijednost (AV) za 8 h-TWA iznad 23.1 g/m3.
In recent years, under-vacuum sealing (UVS) and containers with formalin encapsulated in the lid have been proposed for the reduction of occupational exposure to airborne formaldehyde (FA) in ...healthcare environments.
We are presenting a study focused on the assessment of FA in hospitals: an automatic sampling system was set, different sampling devices were compared, and the concentration of FA was assessed, following its use in different scenarios.
Three different devices for sampling/measuring FA were compared. They are based on: 1. silica gel cartridges impregnated with 2,4-dinitrophenylhydrazine (2,4-DNPH); 2. SPME® fiber using O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine; 3. direct reading commercial instrumentation. Three typical scenarios using FA were investigated: operating theatres where small biopsies are soaked into closed-circuit system 4% FA containers, secretariat of pathology laboratories during the registration of biopsies and pathology laboratories during the filling procedure by UVS and the slicing of biopsies.
The automatic sampling system allowed short-, long-, and in continuous-sampling time to measure airborne FA. Different sampling devices provided comparable results when tested to assess FA concentration ranging from 0.020-0.320 ppm in a test chamber, although the devices based on 2,4-DNPH were the best in terms of sensitivity and accuracy. The results of 246 samples showed that the FA concentration was less than 0.04 ppm in 91% of the measurements.
The automatic methods efficiently allow sampling and measurement of FA in hospital settings. When using safe practices, the concentration of FA is well below occupational limit values.
Formaldehyde (FA) is a chemical compound commonly used in anatomical pathology laboratories as a tissue preservative, and it is common and epidemiologically related to cancer. Therefore, the ...personnel resident in the anatomical pathology laboratories is among the workers most exposed to FA and its related cancer and non-cancerogenic risk. Thus, risk assessment, cancerogenic and non-cancerogenic, and a careful occupational exposure assessment are recommended. In this study, FA was monitored in an Italian anatomical pathology laboratory to perform an occupational exposure assessment, according to the UNI EN 689:219, and to determine the Hazard Quotient (HQ) and the Lifetime Cancer Hazard Risk (LCHR) for carcinogenic and non-carcinogenic risk assessment, respectively. The exposure observed for pathologists and technicians is lower than the EU Occupational exposure limit mandatory (0.62 mg/m3), and both group of workers are in Compliance with it. Nevertheless, concerning the risk assessment, both the HQs and the LCHRs resulted in being higher (1.3 and 1.6 HQ and 3.2x10-5 and 3.9x10-5, for pathologists and technicians, respectively) than the ones observed in similar scenarios. This study shows how the exposure assessment to FA could face striving situations in terms of workers' health safeguard, due to the differences among occupational limits recommended and the high health risks, especially in the healthcare field.
Formaldehid je kemijski spoj koji se obično koristi u laboratorijima za anatomsku patologiju kao konzervans za čuvanje tkiva, a često ga se povezuje s rakom. Osoblje u takvim laboratorijima najizloženije je formaldehidu i s njim povezanom raku, a i nekancerogenom riziku. Stoga se preporuča procjena rizika, kancerogenih i nekancerogenih, a također i procjena izloženosti na radu. Ova studija pratila je formaldehid u jednom talijanskom laboratoriju za patologiju kako bi se procijenila izloženost na radu prema UNI EN 689:219 i utvrdio kvocijent opasnosti (HQ) kao i doživotnog rizika od raka (LCHR) te kancerogeni i nekancerogeni rizici. Izloženost patologa i tehničara bila je niža od Europske obvezne granice za izloženost na radu (0.62 mg/m3) i obje skupine bile su ispod te granice. No, ipak, što se tiče procjene rizika, oba parametra HQ i LCHR bila su viša (1.3 i 1.6 HQ, i 3.2x10-5 i 3.9x10-5 za patologe te tehničare, tj. viša od drugih zamijećenih u sličnim situacijama. Studija prikazuje kako procjena izloženosti formaldehidu može pomoći u očuvanju zdravlja radnika utvrđivanjem odstupanja od preporučenih graničnih vrijednosti i posljedično visokih rizika za zdravlje, posebno u zdravstvu.
PDF
