We study the frictional behavior of both elastic and viscoelastic thin coatings bonded to a seemingly rigid substrate and sliding against a rough profile in the presence of Coulomb friction at the ...interface. The aim is to explore the effect of the coupling between the normal and tangential displacement fields arising from the finiteness of the material thickness and to quantify the contribution this can have on energy losses.
We found that, due to normal–tangential coupling, asymmetric contacts and consequently additional friction are observed even for purely elastic layers, indeed associated with zero bulk energy dissipation. Furthermore, enhanced viscoelastic friction is reported in the case of viscoelastic coatings due to coupling, this time also entailing larger bulk energy dissipation.
Geometric coupling also introduces additional interactions involving the larger scales normal displacements, which leads to a significant increase of the contact area, under given normal load, compared to the uncoupled contacts.
These results show that, in the case of contact interfaces involving thin deformable coating bonded to significantly stiffer substrate, the effect of interfacial shear stresses on the frictional and contact behavior cannot be neglected.
Cell entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) depends on binding of the viral spike (S) proteins to angiotensin-converting enzyme 2 and on S protein priming by TMPRSS2. ...Inhibition of TMPRSS2 may work to block or decrease the severity of SARS-CoV-2 infections. Intriguingly, TMPRSS2 is an androgen-regulated gene that is up-regulated in prostate cancer where it supports tumor progression and is involved in a frequent genetic translocation with the ERG gene. First- or second-generation androgen-deprivation therapies (ADTs) decrease the levels of TMPRSS2. Here we put forward the hypothesis that ADTs may protect patients affected by prostate cancer from SARS-CoV-2 infections.
We extracted data regarding 9280 patients (4532 males) with laboratory-confirmed SARS-CoV-2 infection from 68 hospitals in Veneto, one of the Italian regions that was most affected by the coronavirus disease 2019 (COVID-19) pandemic. The parameters used for each COVID-19-positive patient were sex, hospitalization, admission to intensive care unit, death, tumor diagnosis, prostate cancer diagnosis, and ADT.
There were evaluable 9280 SARS-CoV-2-positive patients in Veneto on 1 April 2020. Overall, males developed more severe complications, were more frequently hospitalized, and had a worse clinical outcome than females. Considering only the Veneto male population (2.4 million men), 0.2% and 0.3% of non-cancer and cancer patients, respectively, tested positive for SARS-CoV-2. Comparing the total number of SARS-CoV-2-positive cases, prostate cancer patients receiving ADT had a significantly lower risk of SARS-CoV-2 infection compared with patients who did not receive ADT (OR 4.05; 95% CI 1.55–10.59). A greater difference was found comparing prostate cancer patients receiving ADT with patients with any other type of cancer (OR 4.86; 95% CI 1.88–12.56).
Our data suggest that cancer patients have an increased risk of SARS-CoV-2 infections compared with non-cancer patients. However, prostate cancer patients receiving ADT appear to be partially protected from SARS-CoV-2 infections.
•SARS-CoV-2-infected men have a worse clinical outcome than women.•Cancer patients have an increased risk of SARS-CoV-2 infection.•Prostate cancer patients receiving androgen-deprivation therapies appear to be partially protected from the infection.
In this work, a numerical method has been developed to investigate the adhesionless contact mechanics between rough surfaces. To solve the elastic problem a boundary elements approach is used with ...self-equilibrated square elements. The domain of integration is discretized developing an “intelligent” adaptive mesh and obtaining a considerable memory saving. The numerical convergence of the method has been verified by comparing the results with the Hertzian solution and by checking the stress probability distribution at the contact interface. The methodology has been then utilized to analyse the contact between an elastic flat substrate and a periodic numerically generated self-affine fractal rigid surface. The fractal surface has been generated by employing spectral methods. The results of our investigation supports the findings of some analytical theories (
Persson, 2001) and numerical findings (
Yang et al., 2006; Hyun et al., 2004; Carbone and Bottiglione, 2008; Campana and Muser, 2007) in terms of linearity between contact area and load and stress probability distributions.
In this paper, we study the dynamic behavior of a Rubber-Layer Roller Bearing (RLRB) interposed between a spring-mass elemental superstructure and a vibrating base. Thanks to the viscoelastic rolling ...contact between the rigid rollers and the rubber layers, the RLRB is able to provide a nonlinear damping behavior. The effect of the RLRB geometric and material parameters is investigated under periodic base excitation, showing that both periodic and aperiodic responses can be achieved. Specifically, since the viscoelastic damping is non-monotonic (bell shaped), there exist system dynamic conditions involving the decreasing portion of the damping curve in which a strongly nonlinear behavior is experienced. In the second part of the paper, we investigate the effectiveness of the nonlinear device in terms of seismic isolation. Focusing on the mean shock of the Central Italy 2016 earthquake, we opportunely tune the material and geometrical RLRB parameters, showing that a significant reduction of both the peak and root-mean-square value of the inertial force acting on the superstructure is achieved, compared to the best performance of a linear base isolation system.
We investigate the dynamic behavior of a regular array of in-plane elastic supports interposed between a sliding rigid body and a rigid substrate. Each support is modelled as a mass connected to a ...fixed pivot by means of radial and tangential elastic elements. Frictional interactions are considered at the interface between the supports and the sliding body. Depending on the specific elastic properties of the supports, different dynamic regimes can be achieved, which, in turn, affect the system frictional behavior. Specifically, due to transverse microscopic vibration of the supports, a lower friction force opposing the macroscopic motion of the rigid body can be achieved compared to the case where no supports are present and rubbing occurs with the substrate. Furthermore, we found that the supports static orientation plays a key role in determining the frictional interactions, thus offering the chance to specifically design the array aiming at controlling the resulting interfacial friction force.
During the last few years, the scientific community has been debating about which theory of contact between rough surfaces can be considered as the most accurate. The authors have been attracted by ...such a discussion and in this paper try to give their personal thought and contribution to this debate. We present a critical analysis of the principal contact theories of rough surfaces. We focus on the multiasperity contact models (which are all based on the original idea of Greenwood and Williamson (GW) 1966. Proc. R. Soc. London A 295, 300), and also briefly discuss a relatively recent contact theory developed by Persson 2001. J. Chem. Phys. 115, 3840. For small loads both asperity contact models and Persson's theory predict a linear relation between the area of true contact and the applied external load, but the two theories differ for the constant of proportionality. However, this is not the only difference between the two approaches. Indeed, we show that the fully calculated predictions of asperity contact models very rapidly deviates from the predicted linear relation already for very small and in many cases unrealistic vanishing applied loads and contact areas. Moreover, this deviation becomes more and more important as the PSD
breadth parameter
α
(as defined by Nayak) increases. Therefore, the asymptotic linear relation of multiasperity contact theories turns out to be only an academic result. On the contrary, Persson's theory is not affected by
α
and shows a linear behavior between contact area and load up to 10–15% of the nominal contact area, i.e. for physical reasonable loads. The authors also prove that, at high separation, all multiasperity contact models, which take into account the influence of summit curvature variation as a function of summit height, necessarily converge to a (slightly) improved version of the GW model, which, therefore, remains one of the most important milestones in the field of contact mechanics of rough surfaces.
Objective: Dispositional optimism, a stable expectation that good things will happen, has been shown to improve health outcomes in a wide range of contexts, but very little research has explored the ...impact of optimism on post-disaster health and well-being.
Design: Data for this study come from the Centers for Disease Control and Prevention's Public health systems and mental health community recovery (PHSMHCR) Survey. Participants included 3216 individuals living in counties affected by the April 2011 tornado outbreak in Mississippi and Alabama.
Main outcome measures: This study assesses the effect of dispositional optimism on post-disaster recovery and mental health.
Results: Dispositional optimism was found to have a positive effect on personal recovery and mental health after the disaster. Furthermore, it moderated the relationship between level of home damage and personal recovery as well as the relationship between home damage and post-traumatic stress disorder (PTSD), with stronger effects for those with increased levels of home damage.
Conclusions: The utility of screening for optimism is discussed, along with the potential for interventions to increase optimism as a means of mitigating adverse mental health effects and improving the recovery of individuals affected by disasters and other traumatic events.
•Nonlinear bell-shaped damping and cubic stiffness may increase the base isolation.•Effective isolation from broader frequency bandwidth is found in nonlinear system.•Steep viscoelastic damping ...decrease at high velocity entails self-excited vibration.
The aim of this paper is to assess the effectiveness of nonlinear viscoelastic damping in controlling base-excited vibrations. Specifically, the focus is to investigate the robustness of the nonlinear base isolation performance in controlling the system response due to a wide set of possible excitation spectra. The dynamic model is derived to study a simple structure whose base isolation is provided via a Rubber-Layer Roller Bearing (RLRB) (rigid cylinders rolling on rigid plates with highly damping rubber coatings) equipped with a nonlinear cubic spring, thus presenting both nonlinear damping and stiffness. We found that, under periodic loading, due to the non-monotonic bell-shaped viscoelastic damping arising from the viscoelastic rolling contacts, different dynamic regimes occur mostly depending on whether the damping peak is overcome or not. Interestingly, in the former case, poorly damped self-excited vibrations may be triggered by the steep damping decrease.
Moreover, in order to investigate the robustness of the isolation performance, we consider a set of real seismic excitations, showing that tuned nonlinear RLRB provide loads isolation in a wider range of excitation spectra, compared to generic linear isolators. This is peculiarly suited for applications (such as seismic and failure engineering) in which the specific excitation spectrum is unknown a priori, and blind design on statistical data has to be employed.
We study the peeling process of a thin viscoelastic tape from a rigid substrate. Two different boundary conditions are considered at the interface between the tape and the substrate: stuck adhesion, ...and relative sliding in the presence of frictional shear stress. In the case of perfectly sticking interfaces, we found that the viscoelastic peeling behavior resembles the classical Kendall behavior of elastic tapes, with the elastic modulus given by the tape high-frequency viscoelastic modulus. Including the effect of frictional sliding, which occurs at the interface adjacent to the peeling front, makes the peeling behavior strongly dependent on the peeling velocity. Also, at sufficiently small peeling angles, we predict a tougher peeling behavior than the classical stuck cases. This phenomenon is in agreement with recent experimental evidences indicating that several biological systems (e.g. geckos, spiders) exploit low-angle peeling to control attachment force and locomotion.
This review summarizes recent advances in the area of tribology based on the outcome of a Lorentz Center workshop surveying various physical, chemical and mechanical phenomena across scales. Among ...the main themes discussed were those of rough surface representations, the breakdown of continuum theories at the nano- and microscales, as well as multiscale and multiphysics aspects for analytical and computational models relevant to applications spanning a variety of sectors, from automotive to biotribology and nanotechnology. Significant effort is still required to account for complementary nonlinear effects of plasticity, adhesion, friction, wear, lubrication and surface chemistry in tribological models. For each topic, we propose some research directions.
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