Landslide databases on a national scale are an important tool for good spatial planning and for planning prevention measures or remediation activities. We have developed a modern national landslide ...database that enabled better landslide occurrence understanding, and will in the future help to assess landslide hazard, risk, potential damage, and enable more efficient landslide mitigation. In the paper landslide database construction steps and their properties are described. Following the collection of the landslide data from various sources and their input into the database the consistency of the database was assessed. Based on the data collected we have assessed basic statistical landslide properties, such as their overall spatial distribution, size and volume and the relation between them, landslide distribution in relation to engineering-geological units and different land-use, and past landslide mitigation activities. Analysis of landslide distribution also indicated areas in Slovenia where no landslide mapping was performed in the past, yet it should be, due to the high landslide susceptibility of these areas. Consequentially future national activities in relation to landslide problems should be governed primarily based on the findings of the database analyses to achieve the highest efficiency.
•A modernised national landslide database is presented and described.•Basic statistics on landslide spatial occurrence was assessed.•In 21 out of 211 Slovenian municipalities landslide density is larger than 1LS/km2.•Size and volume landslide distribution was analysed.•Area to volume log–log relation can be defined with V=0.9223×A1.1996.
The thematic deals with the development of data model for the sustainable management of mineral resources in Slovenia. In the paper the design of the conceptual, logical and physical data modelling ...is presented, and as its result, an entity-relationship (E-R) data model shown. The transfer of archive data to computer environment and the construction of final application allow the user a simple overview of data and various analyses of them. Data model of mineral resources of Slovenia comprises over a hundred tables and meaningfully combines all relevant information on the mineral resources, which in future can effectively contribute to reducing the dependence on external Slovenian market. The developed data model is coherent with the European INSPIRE directive for geospatial data. Model meets the needs of the target groups of users who implemented a policy of sustainable management of mineral resources in Slovenia. By constructing this information system we are approaching the environment more friendly and economically efficient exploitation of mineral resources, avoiding the conflicts between satisfying the market demands and interests of other activities in the Slovenian area.
Primary and secondary mineral resources are of strategic importance for the EU. Most EU countries (including Slovenia) are already part of the pan-European Minerals Intelligence Network which ...provides consistent and organized data information on primary and secondary mineral resources on the European level. It was established in previous projects as EuroGeoSource, Minerals4EU, ProSUM, Mica and ORAMA. The Eastern and south Eastern European (ESEE) region represents a gap in this network, but at the same time is also identified as one of most important strategic regions for the EU with great potential for mineral supply. The large concerns are aiming to expand their business to the region, but access to relevant data interesting for the investors is still not available. There is a need for surveyed and unified mineral resources data. In the framework of RESEERVE (EIT RM KAVA project, duration 1.4.2018-31.3.2021), national mineral resources data of six task partners from West Balkan countries (Albania, Bosnia and Herzegovina, Croatia, Serbia, Montenegro and Macedonia) were implemented and harmonized with INSPIRE directive (European directive for organizing spatial data). Since EU directives are mandatory for members only and West Balkan countries are not yet targeted (except Croatia), they are still interested in their implementation. For that reason the main project goal is the creation of the West Balkan Mineral Register, provided by national data providers, which will represent a starting point to integrate the ESEE region into existing EU data platforms and bring it closer to common minerals market. Regional mineral data will become more accessible and relevant. The goal of the project is to anticipate the future supply and demand for minerals, particularly regarding critical minerals and therefore to contribute to the sustainable mineral supply in Europe. Leading partner for RESEERVE project is Geological Survey of Slovenia (GeoZS), which has identified relevant data providers and examined data quantity, quality, and format. GeoZS will synthesize primary and secondary raw material data into common West Balkan Mineral Register and test the harvesting of data in INSPIRE compliant European data model. The scenarios drawn up in the project will be available through the European Geological Data Infrastructure (EGDI), which will offer easy access to existing mineral data. EGDI provides access to Pan-European and national geological datasets and services from the Geological Survey Organizations of Europe. Through EGDI data from several European data harmonization projects are accessible. EGDI was launched in June 2016 in a Version 1 and has since then been extended to include more data sets, including mineral resources. The article is mostly focused on workflow harmonizing the data and spreading IT knowledge of mapping the national primary and secondary minerals data to already existing European data model and developing national relational databases, that fit into European common database structure. Data harmonization was already performed through national training workshops to assist task partners in taking the first step toward INSPIRE directive implementation.
Primary and secondary mineral resources are of strategic importance to the EU economy. Montenegro, as a country candidate for membership in the EU, is required to follow (and later to implement) ...European policies, strategies as well as initiatives, including those related to mineral resources and the mining sector. The importance of providing access to mineral raw materials in the future is recognized by the EU, as well as meeting the needs of European industry, maintaining employment and ensuring further development. Considering the overall economic situation in Montenegro, it is important to encourge the mining sector and other industries based on the use of mineral resources in making a greater contribution to the development and sustainability of society as a whole and also increase the share of national GDP. The potential for discovery and utilization of primary and secondary mineral resources in Montenegro is demonstrated. The most important metallic mineral resources are bauxite, lead and zinc, while conventional energy resources include coal (oil and gas potential has yet to be proven). In addition, there are abundant non-metallic mineral raw materials - industrial minerals and construction materials. Secondary mineral resources, especially aluminous red mud (bauxite residue), are also significant and have been the subject of research in recent years. Tailings from flotation processes at operating and abandoned lead and zinc mines might also be of interest for metal recovery. Bottom and flay ash from thermal power plants, slag from steel production, as well as marlstone and limestone from the hanging wall of coal deposits may also have potential. Waste rocks could be used particularly for secondary aggregate production. A database was developed and the most important deposits of primary and secondary mineral resources in Montenegro were mapped during the RESEERVE project. Mineral data were harmonised so as to be INSPIRE compliant. In addition, some novel geochemical exploration results of secondary mineral resources are presented.
Skrb za pitno vodo Cerar, Sonja; Cosma, Claudia; Polajnar Horvat, Katarina ...
2014
eBook
Open access
Safeguarding Drinking WaterLjubljana's water resources lie in the immediate vicinity of built-up urban areas or even below them. For decades, they have been safeguarded as water-protection areas, ...which are specified by implementing regulations. However, formal protection through regulations is insufficient if the goal is to manage these sources in a sustainable manner. One of the most important goals of sustainable management is maintaining suitable provision of fresh drinking water without using any technological procedures to
Hydrogeological investigations of groundwater are based on large amount of qualitative and quantitative data (hydrological, hydrogelological, geological, pedological, geomorfological, ...meteorological…), information about topography, land use, antropogenic elements and ecosystems, which demands a complex approach to modeling and organizing information into some logical structure of all purpose data model, useful on local, regional and national level. For that purpose at Geological survey of Slovenia we established a Database of hydrogeolocial data to define groundwater bodies of Slovenia in which all significant data of groundwater bodies, aquifers and hydrogeological objects are available. Digital storage of attributive data enables uniformity of standards for collecting, analyzing and management of data, their spatial presentation and distribution, connection with other information systems and important decision – making future analysis.
Purpose
To develop quantitative molecular imaging biomarkers of immune-related adverse event (irAE) development in malignant melanoma (MM) patients receiving immune-checkpoint inhibitors (ICI) imaged ...with
18
F-FDG PET/CT.
Methods
18
F-FDG PET/CT images of 58 MM patients treated with anti-PD-1 or anti-CTLA-4 ICI were retrospectively analyzed for indication of irAE. Three target organs, most commonly affected by irAE, were considered: bowel, lung, and thyroid. Patient charts were reviewed to identify which patients experienced irAE, irAE grade, and time to irAE diagnosis. Target organs were segmented using a convolutional neural network (CNN), and novel quantitative imaging biomarkers — SUV percentiles (SUV
X%
) of
18
F-FDG uptake within the target organs — were correlated with the clinical irAE status. Area under the receiver-operating characteristic curve (AUROC) was used to quantify irAE detection performance. Patients who did not experience irAE were used to establish normal ranges for target organ
18
F-FDG uptake.
Results
A total of 31% (18/58) patients experienced irAE in the three target organs: bowel (
n
=6), lung (
n
=5), and thyroid (
n
=9). Optimal percentiles for identifying irAE were bowel (SUV
95%
, AUROC=0.79), lung (SUV
95%
, AUROC=0.98), and thyroid (SUV
75%
, AUROC=0.88). Optimal cut-offs for irAE detection were bowel (SUV
95%
>2.7 g/mL), lung (SUV
95%
>1.7 g/mL), and thyroid (SUV
75%
>2.1 g/mL). Normal ranges (95% confidence interval) for the SUV percentiles in patients without irAE were bowel 1.74, 2.86 g/mL, lung 0.73, 1.46 g/mL, and thyroid 0.86, 1.99 g/mL.
Conclusions
Increased
18
F-FDG uptake within irAE-affected organs provides predictive information about the development of irAE in MM patients receiving ICI and represents a potential quantitative imaging biomarker for irAE. Some irAE can be detected on
18
F-FDG PET/CT well before clinical symptoms appear.
Germline aberrations in the CDKN2A gene are observed in 20%–40% of families susceptible to melanoma. Positive CDKN2A status is associated with early age of onset of melanoma, multiple primary ...melanomas, and pancreatic cancer. We report here a melanoma patient with a germline mutation c.68G>A p.(Gly23Asp) in CDKN2A who had a history of multiple cutaneous melanomas and a family history consistent with familial atypical multiple mole melanoma (FAMMM) syndrome. He developed oligometastatic disease with BRAF-positive melanoma metastases in soft tissue and gallbladder and was treated with surgical resection followed by combination therapy of PD-1 and CTLA-4 immune checkpoint inhibitor, which resulted in good remission. Molecular analysis of all primary melanomas and both metastatic sites revealed the same BRAF c.1799T>A p.(Val600Glu) V600E mutations.
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