To perform a meta-analysis of randomized controlled trials (RCTs) assessing the benefit of providing branched chain amino acid (BCAA)-enriched nutrition to improve hepatic function in patients ...undergoing hepatic operation.
The electronic databases of PubMed, Springerlink, the Chinese Biomedical Database (CBM), the Cochrane Library, and the China National Knowledge Infrastructure (CNKI) were searched for relevant RCTs using the following search terms: nutritional support, enteral nutrition, parenteral nutrition, hepatic/liver surgery, liver cirrhosis, cancer, hepatectomy, and liver transplantation. The quality of the retrieved RCTs was assessed according to the scale developed by the Cochrane Collaboration. The meta-analysis was conducted using RevMan software, version 5.2.
A total of 11 relevant RCTs, representing 510 patients, were included in the meta-analysis. Compared to patients in the control (normal nutrition) group, the patients in the BCAA group experienced an effective improvement in hepatic functio
We report the synthesis of ZnIn
2
S
4
/AgIn
5
S
8
(ZIS/AIS) heteromicrospheres with tailorable composition and controllable band gap
via
partial cation exchange for the first time. Detailed studies ...of the as-prepared samples were carried out using SEM, TEM, STEM-EDS, XRD and layer-by-layer depth XPS analysis. Based on these results, possible cation exchange was proposed, and a critical concentration of Ag
+
in the crystals was identified, below which cation exchange cannot occur. Besides, an enhanced photodegradation mechanism was discussed by analyzing the UV-vis-NIR reflectance spectra and the band structure, illustrating that an appropriate thickness of the AIS layer is beneficial to the generation of active species thus favoring the degradation reaction. Further application of dye degradation demonstrated a remarkable photodegradation rate up to 99.2%. Our results shed light on how the cation exchange occurs between ternary and binary crystals, which may open a new avenue to the field for synthesizing materials at the micro-scale.
Here we report a new protocol for synthesizing ZnIn
2
S
4
/AgIn
5
S
8
heteromicrospheres with an excellent photodegradation rate
via
partial cation exchange.
Asymmetrical thin membranes of SrCe sub(0.95)Y sub(0.05)O sub(3-d) (SCY) were prepared by a conventional and cost-effective dry pressing method. The substrate consisted of SCY, NiO and soluble starch ...(SS), and the top layer was the SCY. NiO was used as a pore former and soluble starch was used to control the shrinkage of the substrate to match that of the top layer. Crack-free asymmetrical thin membranes with thicknesses of about 50 km and grain sizes of 5-10 km were successfully pressed on to the substrates. Hydrogen permeation fluxes (J sub(H) sub(2)) of these thin membranes were measured under different operating conditions. At 950 C, J sub(H) sub(2) of the 50 km SCY asymmetrical membrane towards a mixture of 80% H sub(2)/He was as high as 7.6 x 10 super(-8) mol/cm super(2) s, which was about 7 times higher than that of the symmetrical membranes with a thickness of about 620 km. The hydrogen permeation properties of SCY asymmetrical membranes were investigated and activation energies for hydrogen permeation fluxes were calculated. The slope of the relationship between the hydrogen permeation fluxes and the thickness of the membranes was -0.72, indicating that permeation in SCY asymmetric membranes was controlled by both bulk diffusion and surface reaction in the range investigated.
Asymmetrical thin membranes of SrCe
0.95Y
0.05O
3−
δ
(SCY) were prepared by a conventional and cost-effective dry pressing method. The substrate consisted of SCY, NiO and soluble starch (SS), and the ...top layer was the SCY. NiO was used as a pore former and soluble starch was used to control the shrinkage of the substrate to match that of the top layer. Crack-free asymmetrical thin membranes with thicknesses of about 50
μm and grain sizes of 5–10
μm were successfully pressed on to the substrates. Hydrogen permeation fluxes (
J
H
2
) of these thin membranes were measured under different operating conditions. At 950
°C,
J
H
2
of the 50
μm SCY asymmetrical membrane towards a mixture of 80% H
2/He was as high as 7.6
×
10
−8
mol/cm
2
s, which was about 7 times higher than that of the symmetrical membranes with a thickness of about 620
μm. The hydrogen permeation properties of SCY asymmetrical membranes were investigated and activation energies for hydrogen permeation fluxes were calculated. The slope of the relationship between the hydrogen permeation fluxes and the thickness of the membranes was −0.72, indicating that permeation in SCY asymmetric membranes was controlled by both bulk diffusion and surface reaction in the range investigated.
Current popular backbones in computer vision, such as Vision Transformers (ViT) and ResNets are trained to perceive the world from 2D images. However, to more effectively understand 3D structural ...priors in 2D backbones, we propose Mask3D to leverage existing large-scale RGB-D data in a self-supervised pre-training to embed these 3D priors into 2D learned feature representations. In contrast to traditional 3D contrastive learning paradigms requiring 3D reconstructions or multi-view correspondences, our approach is simple: we formulate a pre-text reconstruction task by masking RGB and depth patches in individual RGB-D frames. We demonstrate the Mask3D is particularly effective in embedding 3D priors into the powerful 2D ViT backbone, enabling improved representation learning for various scene understanding tasks, such as semantic segmentation, instance segmentation and object detection. Experiments show that Mask3D notably outperforms existing self-supervised 3D pre-training approaches on ScanNet, NYUv2, and Cityscapes image understanding tasks, with an improvement of +6.5% mIoU against the state-of-the-art Pri3D on ScanNet image semantic segmentation.
Heterozygosity of the retinoblastoma gene Rb1 elicits tumorigenesis in susceptible tissues following spontaneous loss of the remaining functional allele. Inactivation of previously studied ...retinoblastoma protein (pRb) targets partially inhibited tumorigenesis in Rb1.sup.+/- mice (1-6). Here we report that inactivation of pRb target Skp2 (refs. 7,8) completely prevents spontaneous tumorigenesis in Rb1.sup.+/-mice. Targeted Rb1 deletion in melanotrophs ablates the entire pituitary intermediate lobe when Skp2 is inactivated. Skp2 inactivation does not inhibit aberrant proliferation of Rb1-deleted melanotrophs but induces their apoptotic death. Eliminating p27 phosphorylation on T187 in p27T187A knock-in mice reproduces the effects of Skp2 knockout, identifying p27 ubiquitination by SCF.sup.Skp2 ubiquitin ligase as the underlying mechanism for Skp2's essential tumorigenic role in this setting. RB1-deficient human retinoblastoma cells also undergo apoptosis after Skp2 knockdown; and ectopic expression of p27, especially the p27T187A mutant, induces apoptosis. These results reveal that Skp2 becomes an essential survival gene when susceptible cells incur Rb1 deficiency.
Heterozygosity of the retinoblastoma gene Rb1 elicits tumorigenesis in susceptible tissues following spontaneous loss of the remaining functional allele. Inactivation of previously studied ...retinoblastoma protein (pRb) targets partially inhibited tumorigenesis in Rb1 super(+/-) mice. Here we report that inactivation of pRb target Skp2 (refs. 7,8) completely prevents spontaneous tumorigenesis in Rb1 super(+/-) mice. Targeted Rb1 deletion in melanotrophs ablates the entire pituitary intermediate lobe when Skp2 is inactivated. Skp2 inactivation does not inhibit aberrant proliferation of Rb1-deleted melanotrophs but induces their apoptotic death. Eliminating p27 phosphorylation on T187 in p27T187A knock-in mice reproduces the effects of Skp2 knockout, identifying p27 ubiquitination by SCF super(Skp2) ubiquitin ligase as the underlying mechanism for Skp2's essential tumorigenic role in this setting. RB1-deficient human retinoblastoma cells also undergo apoptosis after Skp2 knockdown; and ectopic expression of p27, especially the p27T187A mutant, induces apoptosis. These results reveal that Skp2 becomes an essential survival gene when susceptible cells incur Rb1 deficiency.
Heterozygosity of the retinoblastoma gene Rb1 elicits tumorigenesis in susceptible tissues following spontaneous loss of the remaining functional allele. Inactivation of previously studied ...retinoblastoma protein (pRb) targets partially inhibited tumorigenesis in Rb1^sup +/-^ mice1-6. Here we report that inactivation of pRb target Skp2 (refs. 7,8) completely prevents spontaneous tumorigenesis in Rb1^sup +/-^ mice. Targeted Rb1 deletion in melanotrophs ablates the entire pituitary intermediate lobe when Skp2 is inactivated. Skp2 inactivation does not inhibit aberrant proliferation of Rb1-deleted melanotrophs but induces their apoptotic death. Eliminating p27 phosphorylation on T187 in p27T187A knock-in mice reproduces the effects of Skp2 knockout, identifying p27 ubiquitination by SCF^sup Skp2^ ubiquitin ligase as the underlying mechanism for Skp2's essential tumorigenic role in this setting. RB1-deficient human retinoblastoma cells also undergo apoptosis after Skp2 knockdown; and ectopic expression of p27, especially the p27T187A mutant, induces apoptosis. These results reveal that Skp2 becomes an essential survival gene when susceptible cells incur Rb1 deficiency. PUBLICATION ABSTRACT
During ore dressing production, the size of the ore significantly affects the grinding and classification efficiency and is a crucial control parameter. In the past, most ore image detection ...algorithms focused on the detection tasks of high-resolution ore image. At the same time, due to the sparse data set for industrial production applications, the generalization ability and robustness of the model are low, and it has poor performance on tiny ore target detection tasks. To remedy these shortcomings, this paper proposes the ODA-YOLOv5 network model for ore image detection. In this paper, we adopt a multi-scale training strategy to address the difficulty of detecting tiny ores in high-resolution images. A self-built dataset is constructed by fusing multi-scale ore images. The input image size is dynamically adjusted during training to enhance the robustness of the detection model for ore of different scales. In order to improve the performance of the detection algorithm, we introduce the C3-ECA attention module, which fully takes into account the local cross-letter road interactions and considerably reduces the model complexity. Our algorithm achieves approximately 97.9% mAP and approximately 62.11 FPS on the self-built dataset. Our algorithm sufficiently demonstrates the superiority of our detection model algorithm for industrial ore detection.
The precise control of Weyl physics in realistic materials oers a promising avenue to construct accessible topological quantum systems, and thus draw widespread attention in condensed-matter physics. ...Here, based on rst-principles calculations, maximally localized Wannier functions based tight-binding model, and Floquet theorem, we study the light-manipulated evolution of Weyl physics in a carbon allotrope C6 crystallizing a face-centered orthogonal structure (fco-C6), an ideal Weyl semimetal with two pairs of Weyl nodes, under the irradiation of a linearly polarized light (LPL). We show that the positions of Weyl nodes and Fermi arcs can be accurately controlled by changing light intensity. Moreover, we employ a low-energy eective k p model to understand light-controllable Weyl physics. The results indicate that the symmetry of light-irradiated fco-C6 can be selectively preserved, which guarantees that the light-manipulated Weyl nodes can only move in the highsymmetry plane in momentum space. Our work not only demonstrates the ecacy of employing periodic driving light elds as an ecient approach to manipulate Weyl physics, but also paves a reliable pathway for designing accessible topological states under light irradiation.
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