The local coordination environment of catalysts has been investigated for an extended period to obtain enhanced catalytic performance. Especially with the advancement of single-atom catalysts (SACs), ...research on the coordination environment has been advanced to the atomic level. The surrounding coordination atoms of central metal atoms play important roles in their catalytic activity, selectivity and stability. In recent years, remarkable improvements of the catalytic performance of SACs have been achieved by the tailoring of coordination atoms, coordination numbers and second- or higher-coordination shells, which provided new opportunities for the further development of SACs. In this review, the characterization of coordination environment, tailoring of the local coordination environment, and their related adjustable catalytic performance will be discussed. We hope this review will provide new insights on further research of SACs.
In December 2019, a new coronavirus was found in Wuhan, Hubei Province, China, and spread rapidly throughout the country, attracting global attention. On February 11, the World Health Organization ...(WHO) officially named the disease caused by 2019-nCoV coronavirus disease 2019 (COVID-19). With the increasing number of cases, health care workers (HCWs) from all over China volunteered to work in Hubei Province. Because of the strong infectivity of COVID-19, HCWs need to wear personal protective equipment (PPE), such as N95 masks, latex gloves, and protective clothing. Due to the long-term use of PPE, many adverse skin reactions may occur. Therefore, the purpose of this study is to explore the adverse skin reactions among HCWs using PPE.Questionnaires were used for the research; a quantitative study was carried out to determine the incidence of adverse skin reactions among HCWs using PPE.A total of 61 valid questionnaires were collected. The most common adverse skin reactions among HCWs wearing N95 masks were nasal bridge scarring (68.9%) and facial itching (27.9%). The most common adverse skin reactions among HCWs wearing latex gloves were dry skin (55.7%), itching (31.2%), and rash (23.0%). The most common adverse skin reactions among HCWs wearing protective clothing were dry skin (36.1%) and itching (34.4%).When most HCWs wear PPE for a long period of time, they will experience adverse skin reactions. The incidence of adverse skin reactions to the N95 mask was 95.1%, that to latex gloves was 88.5%, and that to protective clothing was 60.7%.
•Our network meta-analysis has sufficiently large sample size (51 RCTs).•Escitalopram is associated with a quicker relief of depression.•Mirtazapine ranks the best after 8-week treatment ...duration.•Amitriptyline and doxepin are nearly the worst choice regardless of treatment durations.
The efficacy ranking of antidepressants for post-stroke depression (PSD) has not been assessed thoroughly yet due to the lack of network meta-analyses with sufficiently large sample size.
Seven databases including PubMed, Embase, CENTRAL, CBM, CNKI, WanFang and VIP were systematically searched for eligible randomized controlled trials (RCTs) regarding nine antidepressants (citalopram, escitalopram, venlafaxine, paroxetine, duloxetine, amitriptyline, doxepin, sertraline and mirtazapine) treating PSD patients. Stata 15 software and R software were utilized for statistical analyses.
51 RCTs were included in this NMA. For the key efficacy outcomes, escitalopram, mirtazapine, sertraline, citalopram, venlafaxine and paroxetine were associated with larger reduction of the Hamilton Depression Scale (HAMD) total score compared with placebo at 2 weeks. Among the nine antidepressants, escitalopram ranked the best while amitriptyline was the least helpful. At 4 weeks, citalopram ranked higher than placebo and the other eight antidepressants. In contrast, amitriptyline and doxepin were associated with minimal reduction of HAMD score. At 8 weeks, changes in HAMD score were significantly greater in nine antidepressants groups compared to placebo group. Besides, mirtazapine ranked higher than citalopram and escitalopram. At endpoint, mirtazapine was related to the highest response rate, followed by venlafaxine and escitalopram, respectively.
No restriction was imposed on doses of every antidepressant.
Escitalopram was associated with a quicker relief of depression, but mirtazapine was probably the best option when it comes to the efficacy of 8-week treatment duration. Amitriptyline and doxepin were nearly the worst choice regardless of the duration (2, 4 or 8 weeks).
Consistent, large-scale operational monitoring of forest height is essential for estimating forest-related carbon emissions, analyzing forest degradation, and quantifying the effectiveness of forest ...restoration initiatives. The Global Ecosystem Dynamics Investigation (GEDI) lidar instrument onboard the International Space Station has been collecting unique data on vegetation structure since April 2019. Here, we employed global Landsat analysis-ready data to extrapolate GEDI footprint-level forest canopy height measurements, creating a 30 m spatial resolution global forest canopy height map for the year 2019. The global forest height map was compared to the GEDI validation data (RMSE = 6.6 m; MAE = 4.45 m, R2 = 0.62) and available airborne lidar data (RMSE = 9.07 m; MAE = 6.36 m, R2 = 0.61). The demonstrated integration of GEDI data with time-series optical imagery is expected to enable multidecadal historic analysis and operational forward monitoring of forest height and its dynamics. Such capability is important to support global climate and sustainable development initiatives.
In this investigation, an easily-operated and cost-effective method is utilized to synthesize biochar in ambient air, and the prepared biochar is used in a novel manner as a milling aid for ...fabricating Mg-biochar composites for hydrogen storage. X-ray diffractometry reveals that increasing the content of palm kernel shell biochar (PKSBC) from 5 wt.% to 20 wt.% enhances the hydrogen absorption performance by increasing the conversion of Mg into MgH
from 83% to 93%. A 40 °C reduction in decomposition temperature of MgH
is recorded from differential scanning calorimetry curves when the content of PKSBC is increased to 20 wt.%. Magnesium is milled and hydrided under the same experimental conditions and used as a reference material. It is proposed that these property enhancements can be attributed to the fact that PKSBC acts as an anti-sticking agent for elemental Mg powders, helping in the achievement of a more dispersed composite with reduced Mg particle size due to its layered-like carbon structure.
Non-alcoholic fatty liver disease (NAFLD) and urinary incontinence (UI) are both highly prevalent and age-related diseases. Nevertheless, the link between NAFLD and UI is unclear. Hence, the study ...was designed to evaluate the association between the NAFLD and UI (including UI types) in a nationally representative sample of United States (US) female adults.
We conducted this study used data from U.S. female adults in the National Health and Nutrition Examination Survey (NHANES) 2017-March 2020 (pre-pandemic) cycles. The diagnosis of NAFLD is based on Vibration controlled transient elastography (VCTE) and absence of know liver diseases and significant alcohol consumption. The diagnosis and types of UI were assessment using a self-report questionnaire. Multivariable logistic regression models were used to analyze the association between NALFD and UI. Stratified analyses based on age, obesity, race, educational level, married status, PIR, and smoking status were conducted.
Of the 2149 participants, the mean (95% CI) age was 53.9 (52.7-55.0), 686 (61.1%) were Non-Hispanic White. UI was significantly more common in participants with NAFLD 490 (64.7%) than those without NAFLD 552 (44.9%). Adjusted for age, race/ethnicity, marital status, educational level, family poverty income ratio (PIR) status, alanine aminotransferase (ALT), aspartate aminotransferase (AST), smoking status, obesity, type 2 diabetes mellitus (T2DM), hypertension and insulin resistance (IR) in a multivariable logistic regression model, NALFD were associated with UI OR: 1.93, 95%CI 1.23-3.02, P = 0.01 and urge UI OR: 1.55, 95%CI 1.03-2.33, P = 0.03, while patients with NAFLD did not show an increased odds in stress UI and mixed UI when compared with those without NAFLD subject (P > 0.05). In the subgroup analyses, NAFLD remained significantly associated with UI, particularly among those participants without obesity (OR: 2.69, 95% CI 1.84-4.00) and aged ≥ 60 years (OR: 2.20, 95% CI 1.38-3.51).
Among US female adults, NAFLD has a strong positive correlation with UI. Given that NAFLD is a modifiable disease, these results may help clinicians to target female patients with NAFLD for treatments and interventions that may help prevent the occurrence of UI and reduce the symptoms of UI.
Motion vector sensors play an important role in artificial intelligence and internet of things. Here, a triboelectric vector sensor (TVS) based on a direct‐current triboelectric nanogenerator is ...reported, for self‐powered measuring various motion parameters, including displacement, velocity, acceleration, angular, and angular velocity. Based on the working mechanism of the contact‐electrification effect and electrostatic breakdown, a continuous DC signal can be collected to directly monitor moving objects free from environmental electromagnetic signal interference existing in conventional self‐powered TVSs with an alternative‐current signal output, which not only enhances the sensitivity of sensors, but also provides a simple solution to miniaturize the sensors. Its sensitivity is demonstrated to be equivalent to state‐of‐the‐art photoelectric technology by a comparative experiment in an intelligent mouse. Notably, an intelligent pen based on the miniaturized TVS is designed to realize motion trajectory tracing, mapping, and writing on the curved surface. This work provides a new paradigm shift to design motion vector sensors and self‐powered sensors in artificial intelligent and internet of things.
The motion vector sensor is designed to monitor variable motion parameters including displacement, velocity, acceleration, angular, and angular velocity. Multifunction motion trajectory tracing, mapping, and writing on the curved surface are also realized through an intelligent pen based on the miniaturized vector sensor.
In situ conversion of mechanical energy into electricity is a feasible solution to satisfy the increasing power demand of the Internet of Things (IoTs). A triboelectric nanogenerator (TENG) is ...considered as a potential solution via building self-powered systems. Based on the triboelectrification effect and electrostatic induction, a conventional TENG with pulsed AC output characteristics always needs rectification and energy storage units to obtain a constant DC output to drive electronic devices. Here, we report a next-generation TENG, which realizes constant current (crest factor, ~1) output by coupling the triboelectrification effect and electrostatic breakdown. Meanwhile, a triboelectric charge density of 430 mC m
is attained, which is much higher than that of a conventional TENG limited by electrostatic breakdown. The novel DC-TENG is demonstrated to power electronics directly. Our findings not only promote the miniaturization of self-powered systems used in IoTs but also provide a paradigm-shifting technique to harvest mechanical energy.
There are multiple sources of reactive oxygen species (ROS) in the cell. As a major site of ROS production, mitochondria have drawn considerable interest because it was recently discovered that ...mitochondrial ROS (mtROS) directly stimulate the production of proinflammatory cytokines and pathological conditions as diverse as malignancies, autoimmune diseases, and cardiovascular diseases all share common phenotype of increased mtROS production above basal levels. Several excellent reviews on this topic have been published, but ever-changing new discoveries mandated a more up-to-date and comprehensive review on this topic. Therefore, we update recent understanding of how mitochondria generate and regulate the production of mtROS and the function of mtROS both in physiological and pathological conditions. In addition, we describe newly developed methods to probe or scavenge mtROS and compare these methods in detail. Thorough understanding of this topic and the application of mtROS-targeting drugs in the research is significant towards development of better therapies to combat inflammatory diseases and inflammatory malignancies.
Deep learning techniques such as convolutional neural networks have largely improved the performance of building segmentation from remote sensing images. However, the images for building segmentation ...are often in the form of traditional orthophotos, where the relief displacement would cause non-negligible misalignment between the roof outline and the footprint of a building; such misalignment poses considerable challenges for extracting accurate building footprints, especially for high-rise buildings. Aiming at alleviating this problem, a new workflow is proposed for generating rectified building footprints from traditional orthophotos. We first use the facade labels, which are prepared efficiently at low cost, along with the roof labels to train a semantic segmentation network. Then, the well-trained network, which employs the state-of-the-art version of EfficientNet as backbone, extracts the roof segments and the facade segments of buildings from the input image. Finally, after clustering the classified pixels into instance-level building objects and tracing out the roof outlines, an energy function is proposed to drive the roof outline to maximally align with the building footprint; thus, the rectified footprints can be generated. The experiments on the aerial orthophotos covering a high-density residential area in Shanghai demonstrate that the proposed workflow can generate obviously more accurate building footprints than the baseline methods, especially for high-rise buildings.
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