Bibliotecas a Sul Agenjo, Xavier; Alvim, Luísa; Barrulas, Joaquina ...
12/2023
Book
Open access
Bibliotecas a Sul é uma obra de investigação e divulgação académica que analisa o fenómeno das bibliotecas nas suas múltiplas vertentes de serviço e uso e pretende elucidar aspetos relacionados com ...as bibliotecas do sul de Portugal continental, no âmbito da missão do CIDEHUS – Centro Interdisciplinar de História, Culturas e Sociedades. Os estudos e contributos são inéditos e realizados especificamente para esta obra, maioritariamente por membros integrados no CIDEHUS, cruzando várias disciplinas na área da biblioteconomia e dos estudos de cultura. Inclui, ainda, uma homenagem a Maria José Moura, bibliotecária eborense e impulsionadora das bibliotecas públicas em Portugal.
Segundo o Manifesto da UNESCO (1994), a biblioteca pública deve «assegurar a cada pessoa os meios necessários para evoluir de forma criativa». As bibliotecas desempenham um papel de primeira linha na ...construção do conhecimento ao providenciar recursos informativos culturais e tecnológicos e abrindo novas portas ao saber. É um organismo vivo que está em constante evolução e transformação sempre com o mesmo objetivo em mente: o de conseguir contribuir para o desenvolvimento da comunidade. A bib...
The use of crop residues as a bioenergy feedstock is considered a potential strategy to mitigate greenhouse gas (GHG) emissions. However, indiscriminate harvesting of crop residues can induce ...deleterious effects on soil functioning, plant growth and other ecosystem services. Here, we have summarized the information available in the literature to identify and discuss the main trade-offs and synergisms involved in crop residue management for bioenergy production. The data consistently showed that crop residue harvest and the consequent lower input of organic matter into the soil led to C storage depletions over time, reducing cycling, supply and availability of soil nutrients, directly affecting the soil biota. Although the biota regulates key functions in the soil, crop residue can also cause proliferation of some important agricultural pests. In addition, crop residues act as physical barriers that protect the soil against raindrop impact and temperature variations. Therefore, intensive crop residue harvest can cause soil structure degradation, leading to soil compaction and increased risks of erosion. With regard to GHG emissions, there is no consensus about the potential impact of management of crop residue harvest. In general, residue harvest decreases CO2 and N2O emissions from the decomposition process, but it has no significant effect on CH4 emissions. Plant growth responses to soil and microclimate changes due to crop residue harvest are site and crop specific. Adoption of the best management practices can mitigate the adverse impacts of crop residue harvest. Longterm experiments within strategic production regions are essential to understand and monitor the impact of integrated agricultural systems and propose customized solutions for sustainable crop residue management in each region or landscape. Furthermore, private and public investments/cooperations are necessary for a better understanding of the potential environmental, economic and social implications of crop residue use for bioenergy production.
Objective
Protein misfolding plays a central role not only in amyotrophic lateral sclerosis (ALS), but also in other conditions, such as frontotemporal dementia (FTD), inclusion body myopathy (hIBM) ...or Paget's disease of bone. The concept of multisystem proteinopathies (MSP) was created to account for those rare families that segregate at least 2 out of these 4 conditions in the same pedigree. The calcium‐dependent phospholipid‐binding protein annexin A11 was recently associated to ALS in European pedigrees. Herein, we describe in detail 3 Brazilian families presenting hIBM (isolated or in combination with ALS/FTD) caused by the novel p.D40Y change in the gene encoding annexin A11 (ANXA11).
Methods
We collected clinical, genetic, pathological and skeletal muscle imaging from 11 affected subjects. Neuroimaging was also obtained from 8 patients and 8 matched controls.
Results
Clinico‐radiological phenotype of this novel hIBM reveals a slowly progressive predominant limb‐girdle syndrome, but with frequent axial (ptosis/dropped head) and distal (medial gastrocnemius) involvement as well. Muscle pathology identified numerous rimmed vacuoles with positive annexin A11, TDP‐43 and p62 inclusions, but no inflammation. Central nervous system was also involved: two patients had FTD, but diffusion tensor imaging uncovered multiple areas of cerebral white matter damage in the whole group (including the corticospinal tracts and frontal subcortical regions).
Interpretation
These findings expand the phenotypic spectrum related to ANXA11. This gene should be considered the cause of a novel multisystem proteinopathy (MSP type 6), rather than just ALS. ANN NEUROL 2021;90:239–252
Background
This systematic review aimed to investigate the radiological features of lymphomas and leukaemias affecting the jaws.
Methods
A systematic literature review was conducted using the ...electronic databases of PubMed, Web of Science and Scopus. Articles that contained sufficient radiographic examinations (periapical, panoramic or computed tomography images) for individual cases were included. Additionally, either immunohistochemical or molecular confirmation was required prior to inclusion. Three authors evaluated and described the image quality and radiological features.
Results
From an initial 1079 articles screened, 129 cases were included, containing 88 tomographic, 76 panoramic and 26 periapical examinations. The quality of the majority of images was sufficient for evaluation. Diffuse large B‐cell lymphoma, Burkitt lymphoma, leukemic infiltration, plasmablastic lymphoma and extranodal Natural killer (NK)/T‐cell lymphoma, nasal type were the most common subtypes. Involved teeth presented with mobility in 37.2% of the cases and a provisional diagnosis of inflammatory/infectious dental disease was considered in 49.2% of cases. Computed tomography exams were available for 76% of the cases, with most presented with an osteolytic lesion with ill‐defined borders. Periosteal reactions were uncommon.
Conclusion
Lymphoma/leukaemia infiltrates of the jaw bones are usually of high‐grade subtypes and rarely present with periosteal reactions.
Lymphomas and leukemias are malignant neoplasms that uncommonly affect the jaws and their radiographic manifestations may contribute to the diagnosis. Objective: To investigate the radiographic ...features of lymphomas and leukemias in the jaw bones. Study Design: systematic review in the electronic databases Pubmed, Web of Science, and Scopus using the key words "lymphoma, leukemia, mandible, maxilla, jaw, gnathic bones", between 2008 and 202. Inclusion criteria: Periapical, panoramic, or computed tomography (CT) images for individual cases and diagnosis of lymphoma/leukemia confirmed by immunohistochemistry. Three authors described the images and evaluated the quality of the radiographic exams. Results: From 1079 reports screened, 130 cases were selected containing 88 tomographic, 78 panoramic, and 26 periapical exams, most of them classified as excellent (54%). Diffuse large B-cell lymphomas NOS (DLBCL), Burkitt lymphoma, leukemic infiltration, and plasmablastic lymphoma were the more common subtypes. Involved teeth presented mobility in 36% and a provisional diagnosis of inflammatory/infectious tooth disease was considered 48% of the cases. Most cases were radiolucent and conventional CT exams were available for 76% of the cases, with hypodense aspect, ill-defined borders, and periosteal reactions were uncommon. Conclusion: Lymphomas with gnathic bone destruction are usually of high-grade subtypes and rarely present periosteal reaction.
The use of dwarf plants in tomato breeding has provided several advantages. However, there are no identified dwarf plants (dd) containing the self-pruning habit (spsp). The aim of this work was to ...obtain future generations, characterize the germplasm, and select potential dwarf plants with a determinate growth habit to obtain Salad-type lines. The work was started by carrying out hybridization, followed by the first, second, and third backcrosses. Once F2BC3 seeds became available, the introgression of the self-pruning gene (spsp) into dwarf plants (dd) began. Three strains of normal architecture and a determinate growth habit were hybridized with two strains of dwarf size and an indeterminate growth habit, thus yielding four hybrids. Additionally, donor genotype UFU MC TOM1, the commercial cultivar Santa Clara, and the wild accession Solanum pennellii were used in the experiment. Agronomic traits, fruit quality, metabolomics, and acylsugars content were evaluated, and dwarf plants with a determinate growth habit were selected. Hybrid 3 exhibited the highest yields. Visual differences between determinate and indeterminate dwarf plant seedlings were observed. It is suggested to carry out five self-pollinations of the best dwarf plant determined and subsequent hybridization with homozygous lines of normal plant architecture and determinate growth habit to obtain hybrids.
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