The "lung and large intestine being interior-exteriorly related" is one of the classical theories in traditional Chinese medicine, which indicates a close correlation between the lung and large ...intestine in physiology and pathology, and plays a pivotal role in guiding the treatment of the lung and bowel diseases. Modern medicine has revealed some connections between the lung and large intestine in tissue origin and mucosal immunity, and preliminarily illuminated the material basis and possible regulatory mechanism of the theory. Recently, this theory has been applied to guide the treatment of refractory lung and intestine diseases such as COVID-19 and ulcerative colitis and has obtained reliable efficacy. Existing research results show that the anatomical homogeneity of lung and large intestine promotes the correlation between lung-bowel mucosal immunity, and mucosal immunity and migration and homing of innate lymphocytes are one of the physiological and pathological mechanisms for lung and large intestine to
To investigate the effect of Chinese medicine Wubi Shanyao pills on sexual function of kidney-yang-deficiency mice induced by hydrocortisone.
Male Kunming mice were injected with hydrocortisone for ...10 days to prepare the kidney-yang-deficiency model, and administrated with Wubi Shanyao pills (0.91, 1.82, 2.73 g/kg) for 9 weeks. The general behaviors of mice (autonomous activity, grasping power) were observed; sexual behaviors (capture, straddle, ejaculation frequency and incubation period) of mice were detected by mating experiment. The serum levels of cortisol, adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E
) and testosterone were measured by ELIZA. The organ indexes of kidney, epididymis, testis and seminal vesicle were calculated. The histomorphology of testis was observed by HE staining. The apoptosis of testis cells was detected by TUNEL; and the expression level of proliferating cell nuclear antigen (PCNA) in testis was detected by immunohi
无比山药丸对氢化可的松致肾阳虚模型小鼠性功能的影响 CHEN, Qingqing; SHAN, Chaowen; SU, Jie ...
Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban,
12/2020, Volume:
49, Issue:
6
Journal Article
This work built a molecular‐level kinetic model for hydrocarbon catalytic cracking, incorporating the catalyst acidity as the parameter to estimate reaction rates. The n‐decane and 1‐hexene ...co‐conversion catalytic cracking process was chosen as the studying case. The molecular reaction network was automatically generated using a computer‐aided algorithm. A modified linear free energy relationship was proposed to estimate the activation energy in a complex reaction system. The kinetic parameters were initially regressed from the experimental data under several reaction conditions. On this basis, the product composition was evaluated for three catalytic cracking catalysts with different Si/Al. The Bronsted acid and Lewis acid as the key catalyst properties were correlated with kinetic parameters. The built model can calculate the product distribution, gasoline composition, and molecular distribution at different reaction conditions for different catalysts. This sensitive study shows that it will facilitate the model‐based optimization of catalysts and reaction conditions according to product demands.
