Extensively used antibiotic ciprofloxacin increases in water environment, which is not efficiently removed by means of conventional adsorbents. MCM-41 has great potential for ciprofloxacin removal. ...There has been little research on ciprofloxacin removal by MCM-41 and their corresponding adsorption/desorption behaviors. In this study, amorphous SiO2, MCM-41 and diamine-functionalized MCM-41 were used as adsorbents to remove ciprofloxacin. In the adsorption process, their adsorption capacity followed the order of SiO2≪MCM-41< diamine-functionalized MCM-41. Ciprofloxacin adsorption behaviors were revealed through the analysis of adsorption isotherms and kinetics model: i. Adsorption process for MCM-41/diamine-functionalized MCM-41 mainly included three steps; and ii. Diamine-functionalized MCM-41 had higher adsorption capacity because of its more and stronger chemical-monolayer adsorption. In the desorption process, strong acid facilitated desorption by inhibiting the interaction between ciprofloxacin and diamine-functionalized MCM-41, and the mechanism was proposed and then supported by salt elution experiment. Last, the breakthrough bed volume and capacity of these absorbents were tested in column operation. Diamine-functionalized MCM-41 had better performance with 550 bed volume and 18.3 mg/g adsorption capacity in the treatment of 5.0 mg/L ciprofloxacin. Both batch and column results demonstrated that diamine-functionalized MCM-41 was highly efficient for ciprofloxacin removal. This study indicates great application prospect of mesoporous silica materials for ciprofloxacin removal and reveals their adsorption/desorption behaviors, which could provide guidance on adsorbent modification/regeneration for antibiotics removal.
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•MCM-41 and N-MCM-41 were efficient for ciprofloxacin removal in batch and column operations.•Ciprofloxacin Adsorption and desorption behaviors by mesoporous silica materials were revealed.•N-MCM-41 had higher adsorption capacity own to more chemical-monolayer adsorption.•Strong acid favored desorption by inhibiting interaction between ciprofloxacin and N-MCM-41.•This study guides adsorbent selection/modification/regeneration for antibiotic removal.
As a prototype tool for slot‐die coating, blade‐coating exhibits excellent compatibility with large‐area roll‐to‐roll coating. A ternary organic solar cell based on PBDB‐T:PTB7‐Th:FOIC blends is ...fabricated by blade‐coating and exhibits a power conversion efficiency of 12.02%, which is one of the highest values for the printed organic solar cells in ambient environment. It is demonstrated that blade‐coating can enhance crystallization of these three materials, but the degree of induction is different (FOIC > PBDB‐T > PTB7‐Th). Thus, the blade‐coated PBDB‐T:FOIC device presents much higher electron mobility than hole mobility due to the very high crystallinity of FOIC. Upon the addition of PTB7‐Th into the blade‐coated PBDB‐T:FOIC blends, the crystallinity of FOIC decreases together with the corresponding electron mobility, due to the better miscibility between PTB7‐Th and FOIC. The ternary strategy not only maintains the well‐matched crystallinity and mobilities, but also increases the photocurrent with complementary light absorption as well as the Förster resonant energy transfer. Furthermore, small domains with homogeneously distributed nanofibers are observed in favor of the exciton dissociation and charge transport. This combination of blade‐coating and ternary strategies exhibits excellent synergistic effect in optimizing morphology, showing great potential in the large‐area fabrication of highly efficient organic solar cells.
A balanced crystallinity of donor and acceptor is finely controlled by combining blade‐coating and ternary strategies in a PBDB‐T:PTB7‐Th:FOIC‐based organic solar cell, resulting in well‐matched hole and electron mobilities with a power conversion efficiency of 12.02%.
This paper uses ANSYS Fluent to simulate the heat dissipation of a phase change material (PCM)-based cooling system combined with novel spiral fins for a single battery cell. Compared with a circular ...fin, a spiral fin with the same contact length can reduce the battery temperature by 0.72 °C, and has a superior temperature uniformity. For the PCM-based system with spiral fins, increasing the spiral width from 2 mm to 8 mm can reduce the battery temperature from 41.27 °C to 39.9 °C. As the number of spiral turns increases from two to eight, the maximum temperature rise of the battery shows a downward trend, and six turns can effectively satisfy the heat dissipation requirements of the battery. With respect to the effect of ambient temperature on the cooling performance, the system with a PCM-spiral fin still exhibits optimal cooling effectiveness compared with the pure PCM and PCM-circular systems.
Phosphorescent near‐infrared (NIR) organic light‐emitting devices (OLEDs) have drawn increasing attention for their promising applications in the fields such as photodynamic therapy and night‐vision ...readable displays. Here, three simple phosphorescent Pt(II) complexes are synthesized, and their intermolecular interactions are investigated in crystals and neat films by X‐ray single crystal diffraction and grazing‐incidence wide‐angle X‐ray scattering, respectively. The photophysical properties, molecular aggregation (including Pt–Pt interaction), molecular packing orientation, and electron transport ability are all influenced by the strong intermolecular hydrogen bonds. Consequently, the nondoped OLEDs based on tBu‐Pt and F‐Pt show electroluminescent emissions in NIR region with the highest external quantum efficiencies of 13.9% and 16.7%, respectively.
Because of enhanced molecular aggregations induced by strong intermolecular hydrogen bonds, a simple Pt(II) complex neat film shows near‐infrared (NIR) emission with high photoluminescence quantum yield, improved electron transport ability, and preferred molecular orientation. The related nondoped organic light‐emitting device (OLED) exhibits the near‐infrared (NIR) emission with a peak external quantum efficiency of 16.7%.
The development of high-performance direct-Z Scheme heterojunctions as photocatalysts is the focus of current research, and it is also an effective way to improve the performance of photocatalysts. ...Based on this, we use density functional theory (DFT) to predict two-dimensional (2D) XSe
2
/SiH (X = Zr, Sn) van der Waals (vdW) heterojunction as a potential direct Z-scheme heterojunction photocatalyst. The results indicate that both heterojunctions exhibit a typical Type-II band edge arrangement. Furthermore, the small band gap and built-in electric field of the heterojunctions facilitate electronic transitions between the valence band (VB) and conduction band (CB), thereby increasing the probability of interlayer electron–hole (e
−
-h
+
) recombination within the heterojunction. This process is beneficial for the formation of direct-Z Scheme heterojunctions. In addition, the XSe
2
/SiH (X = Zr, Sn) heterojunction exhibits remarkable photogenerated electron and hole driving forces, along with exceptional light-trapping capabilities. Therefore, XSe
2
/SiH (X = Zr, Sn) heterojunction is a potential new photocatalyst.
Graphical Abstract
The Measurement and Treatment Research to Improve Cognition Schizophrenia Consensus Cognitive Battery (MCCB) has also been proposed for use in clinical trials to assess cognitive deficits in patients ...with bipolar disorder (BD). The aim of this study was to evaluate cognitive function assessed by the MCCB in BD.
A literature search of the PubMed, Embase, PsycINFO, SCI, Cochrane Library databases and the Cochrane Controlled Trials Register was conducted. Case reports, reviews and meta-analyses were excluded and a systematic review of the remaining studies of cognitive function in BD was carried out. The cognitive outcome measure was the MCCB, including 7 domains and overall cognition. A random-effects model was applied.
Eighty eight studies were initially identified. Seven clinical studies comprising a total of 487 patients and 570 healthy controls (HC) were included in the meta-analysis. Patients with BD performed worse than HC in overall cognition and processing speed with a large effect size of >0.8; with a medium effect size (0.5-0.8) in attention, working memory, verbal learning and visual learning; and with a small effect size (0.2-0.5) in reasoning and problem solving and social cognition.
Patients with BD performed worse than HC in overall cognition and all cognitive domains of the MCCB. Cognitive deficits in domains of processing speed and working memory are prominent in patients with BD. Our findings suggest that MCCB can be usefully applied in BD.
Acute ST-segment elevation myocardial infarction (STEMI) remains a serious life threatening event with a poor prognosis due to myocardial ischemia/reperfusion injury despite coronary ...revascularization. Extracorporeal cardiac shock wave (ECSW) is a safe, effective and non-invasive new method for the treatment of cardiovascular diseases. The current results show that extracorporeal cardiac shock wave provides a new treatment option for patients with severe and advanced coronary heart disease. However, there are relatively few clinical studies on the application of in vitro cardiac shock waves in patients with myocardial ischemia-reperfusion injury. We hypothesized that extracorporeal cardiac shock therapy would also be effective in reducing clinical endpoints in patients with STEMI reperfusion.
This study is order to provide a new therapeutic method for patients with myocardial ischemia-reperfusion injury and reveal the possible mechanism of ECSW for ischemia-reperfusion injury.
CEECSWIIRI is a single-center, prospective randomized controlled trial that plans to enroll 102 eligible patients with acute ST-segment elevation myocardial infarction reperfusion. Eligible patients with STEMI reperfusion will be randomly divided into external cardiac shock therapy (ECSW) trial group and blank control group. The blank control group will receive optimal drug therapy, and the experimental group will receive optimal drug therapy combined with ECSW. The shock wave treatment plan will be 3-month therapy, specifically 1 week of treatment per month, 3 weeks of rest, 3 times of ECSW in each treatment week, respectively on the first day, the third day and the fifth day of the treatment week, lasting for 3 months and follow-up for 2 years. The primary endpoint will be to assess the 2-year improvement in all-cause death, re-hospitalization due to cardiovascular disease, major unintentional cerebrovascular events, including cardiogenic death, myocardial infarction, heart failure, arrhythmia, emergency coronary revascularization, and stroke in patients with STEMI reperfusion. Secondary endpoints will include improvements in angina pectoris, quality of life, cardiac structure and function, coronary microcirculation, and endothelial progenitor cell-derived miR-140-3p in relation to survival outcomes.
ClinicalTrial.gov.org PRS:NCT05624203; Date of registration: November 12, 2022.
In the field of photocatalytic water splitting, the direct Z-scheme heterostructure is regarded as a promising photocatalyst configuration. In this paper, we use density functional theory to predict ...the Ti
2
CO
2
/CrSSe heterostructure as a potential direct Z-scheme heterojunction photocatalyst and investigate its electronic, optical, and heterojunction interface properties. The results show that the Ti
2
CO
2
/CrSSe heterojunction has a strong electrostatic attraction between the electrons in the conduction band of Ti
2
CO
2
and the holes in the valence band of CrSSe due to the small interlayer band gap, which can realize the rapid interlayer electron-hole (e
−
–h
+
) recombination. The redistribution of charge results in a built-in electric field that prevents unwanted electron and hole migration. In addition, the Ti
2
CO
2
/CrSSe van der Waals (vdW) heterojunction exhibits excellent light absorption, and its redox ability has been improved. These properties indicate that Ti
2
CO
2
/CrSSe heterostructure is a promising photocatalyst.
Graphical Abstract
Aim
The extent and specifics regarding cognitive dysfunction in patients with bipolar disorder (BD) or major depressive disorder (MDD) and their unaffected first‐degree relatives (FDR) have not been ...addressed in any single study. The present study compared the cognitive function of patients with BD or MDD, their FDR, and healthy control (HC) individuals.
Methods
The study population comprised adults (aged 18–55 years) with BD, adults with MDD, FDR (children or siblings of patients with BD or MDD), and HC (n = 105, 109, 85, and 95, respectively). The Repeatable Battery for the Assessment of Neuropsychological Status was used to assess neurocognitive functions, with five domains and 12 tests. A Wechsler Adult Intelligence Scale brief form was applied to evaluate IQ. Status of mood was assessed using the Young Mania Rating Scale and the Hamilton Depression Scale.
Results
The mixed model indicated significant variation among the four groups in cognitive function. Cognitive impairments, compared to HC, progressively greater from least to most were found in: FDR, MDD, and BD (F = 32.74, P < 0.001). Years of education correlated with cognitive performance (F = 17.04, P < 0.001), as did IQ (F = 240.63, P < 0.001). The total score for the Hamilton Rating Scale for Depression negatively correlated with cognitive function (F = 5.78, P = 0.017).
Conclusion
Among the study groups, patients with BD had the most severe deficits, followed by MDD patients and FDR. Cognitive deficits could not be associated with a specific psychiatric disorder, but differences in degree were noted.
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