Background: Elevated blood glucose is common in the early stage of stroke. Besides, blood glucose level increases during acute stroke in nondiabetic patients.
Objective: Objective of the study was to ...assess the glycemic status during acute stroke in nondiabetic patients, find the rate of newly developed diabetes during acute stroke and rate of newly developed Impaired Fasting Glucose, Impaired Glucose Tolerance during acute stroke.
Methods: The purposive sampling method was used to identify the patients and by proper history taking, documentary papers and laboratorial support evidenced by HbA1c level less than 6.5% (This means patient to be non diabetic). Data were collected from 100 patients. It was conducted from August, 2018 to February, 2019 in the Department of Medicine of Dhaka Medical College Hospital. The data were collected through questionnaire ,pre-tested earlier and data collection sheet illustrating the glycemic status during acute stroke among the nondiabetic patients.
Results: While analyzing the lab investigations among the respondents, mean HbA1c level was found 5.69± 0.65 mmol/L level which was found normal among the entire patient group. Patients Fasting Blood Sugar(FBS) was tested and mean FBS level was 5.94±0.86. In 62% of the patients, IFG was found, and in 12% of patients, FBS value was found to be diabetic while 26% showed normal glycemic status. Average OGTT(2 hours after 75 gm glucose) impression was 8.53± 2.02 mmol/L. OGTT level was normal among 30%, 54% patients had IGT and 16% of the respondents were found diabetic.
Conclusion: The study finds that, in patients with no history of diabetes who have acute stroke, may develop moderately elevated glucose levels which may affect short term and long term stroke related morbidity and mortality.
J MEDICINE JAN 2021; 22 (1) : 22-26
Strongyloides stercolaris is a common intestinal nematode in tropical and subtropical countries like Bangladesh. The presentation of this infection is nonspecific. Mostly it remains asymptomatic with ...peripheral eosinophilia. Immunocompromised individuals are at high risk of hyper infection to disseminated disease. We present a case of Strongyloides in an immunocompetent patient with features of gastric outlet obstruction. Laboratory findings revealed hypereosinophilia with multiple gastrointestinal ulcers on endoscopy. Biopsy was taken from a gastric ulcer which revealed ulceration and dense infiltration of acute and chronic inflammatory cells along with extensive intestinal metaplasia. There were tiny helminthic bodies within the mucosal glands and on the surface consistent with Strongyloides stercoralis. Routine examination of stool also revealed larvae of Strongyloides stercolaris. J Dhaka Med Coll. 2022; 31(1) : 163-166
Background: Raised blood glucose is common in diabetic patients in early phase of stroke. It is also known that blood glucose level increases during acute stroke in non diabetic patients.
Objective: ...Objective of this study was to assess the association between family history of diabetes and newly developed diabetes, impaired fasting glucose, impaired glucose tolerance during acute stroke in non diabetic patients.
Methods: The purposive sampling method was applied to identify the patients by appropriate history taking about diabetes among the patients and their 1st degree relatives, documentary papers and laboratorial support evidenced by HbA1c level less than 6.5% (This means patient to be non diabetic). Data were collected from 100 patients. The data were collected by questionnaire, pre-tested earlier and data collection sheet illustrating the family history of diabetes mellitus and glycemic status during acute stroke among the nondiabetic patients. It was conducted from January, 2021 to July, 2021 in the Department of Medicine of Dhaka Medical College Hospital.
Results: The study found that, mean age of the patents was 61.76±7.33 years. Family history of Diabetes Mellitus (first degree relative) was found among 48% patients.52% patients did not give family history of Diabetes Mellitus. During analysis of the lab investigations among the participants, mean HbA1c level was found 5.69± 0.65 mmol/L which was found normal among the entire patient group. Patients Fasting Blood Sugar (FBS) was tested and mean FBS level was 5.94±0.86.Among the respondents 48% gave family history(1st degree relative) of Diabetes of which 8.3% revealed normal glycemic status , 66.7% showed IGT and 25.0% were diabetic. On the other hand 52% respondents had no family history of Diabetes, among them 50% showed no glycemic abnormality, 42.3% showed IGT and only 7.7% were diabetic.
Conclusion: In a nutshell, the study finds that, in patients with no history of diabetes who have acute stroke, may develop moderately elevated glucose levels and it is significantly higher in those who have family history of diabetes mellitus.
J Dhaka Med Coll. 2021; 29(1): 38-42
Pre-eclampsia is a disorder of 2nd half of pregnancy, which is characterized by a combination of hypertension, proteinuria and edema, secondary to decreased placental perfusion. Clinical studies ...suggest that there are histopathological changes in the placenta of pre-eclamptic women, compared to normotensive pregnant women. In developing countries, pre-eclampsia causes an estimated 50,000 maternal deaths per year. Only a small number of studies have however, been conducted in Bangladesh.
Objective: To compare the histopathology of placenta in selected pre-eclamptic and normotensive pregnant women.
Methods: 220 pregnant women were selected with inclusion and exclusion criteria from 3 different medical colleges and divided into 2 groups – A study group, consisting of 110 pre-eclamptic women and a control group consisting of 110 normotensive pregnant women. Dietary information was collected by 7 days food frequency questionnaire and food score was determined. Anthropometric and biochemical tests were performed. To evaluate the histopathology of placenta, tissue samples were collected from the placenta after delivery, and were prepared for histopathological studies, by haemotoxylin and eosin stain method. The mean number of areas of syncytial knot formation, the mean number of areas of cytotrophoblastic cell proliferation, the mean number of areas of fibrinoid necrosis, and the mean number of areas of hyalinised villi of pre-eclamptic and normal pregnant women were evaluated.
Results: The mean number of areas of syncytial knot formation, the mean number of areas of cytotrophoblastic cell proliferation, the mean number of areas of fibrinoid necrosis, and the mean number of areas of hyalinised villi were found to be significantly higher in the study group, compared to the control group.
Conclusion: Therefore, mean number of areas of syncytial knot formation, the mean number of areas of cytotrophoblastic cell proliferation, the mean number of areas of fibrinoid necrosis is increased in the placenta of pre-eclamptic women, compared to normotensive pregnant women.
J Dhaka Med Coll. 2021; 30(2) : 189-195
Histoplasmosis is a fungal infection primarily acquired through inhalation, and is rarely encountered outside endemic areas. In non-endemic areas, histoplasmosis poses a diagnostic challenge, ...especially since the presenting lesions can mimic carcinoma and other chronic infections including tuberculosis. We report an unusual case of isolated vocal cord histoplasmosis in a 60 year old immunocompetent man from Bangladesh presenting with hoarseness of voice. DOI: http://dx.doi.org/10.3329/jom.v13i1.10080 JOM 2012; 13(1): 77-81
Fever, chest pain, cough in a young lady usually does not ring any alarm bell. We present here a case of a young lady who had typical symptoms of community acquired pneumonia who initially responded ...to regular antibiotics but later was investigated to have large cell carcinoma. Presentation of lung cancer as non-resolving pneumonia is not a very common phenomenon and diagnosis can present a diagnostic challenge to the clinician. PUBLICATION ABSTRACT
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