Cervical myelography and survey radiography was performed on 12 light breed wobbling foals and a new radiographic measurement method was applied for more accurate diagnosis of cervical vertebral ...instability. Ratios of stenosis of the spinal canal on survey radiography and myelography using relative values in an individual foal were defined on radiograms of lateral flexed position of mid-cervical region, and coincidence between the ratios and histopathological lesions in the cervical spinal cord was investigated. Five of 6 foals had ratios of stenosis on myelography more than 40% at the intervertebral sites where the most severe histopathological lesions were observed. Four of 6 foals had ratios of stenosis on survey radiography more than 40% at the intervertebral sites where the most severe histopathological lesions were observed. False-positive diagnosis of CVI was observed in 1 out of 6 foals without histopathological lesion when both ratios of stenosis on myelography and survey radiography were applied. Although the standard value of 40% should be further investigated, the new radiographic measurement method in this study is very useful in clinical diagnosis of cervical vertebral instability in wobbling foals, and the presence of lesions in the cervical spinal corn and their sites by survey radiography may be estimated more accurately
A Case of Nephroblastoma in a Dog YAMAZOE, Kazuaki; KANESHIMA, Takashi; SASAKI, Nobuo ...
Japanese Journal of Veterinary Anesthesia & Surgery,
1989/10/30, Volume:
20, Issue:
4
Journal Article
A 14 month-old Yorkshire terrier was presented with hyperammonemia and neurological disorder. Helical computed tomographic portography showed a single extrahepatic portosystemic shunt between left ...colic vein and caudal vena cava. Mesenteric portography after laparotomy revealed the other shunt inconsistently visualized around left gastric vein. The both shunts were safely ligated and hyperammonemia was disappeared. This case report shows a rare case of extrahepatic CPSS in a dog and the importance of mesenteric portography especially after shunt ligation, not for missing other shunts.
Charge pumping in SOS-MOS transistors Sasaki, N.
IEEE transactions on electron devices,
1981-Jan., 1981-01-00, 19810101, Volume:
28, Issue:
1
Journal Article
Peer reviewed
The variation of the floating-substrate potential of SOS-MOS transistors is studied by applying frequent pulses to the gate. The minority carriers are injected into the floating substrate by charge ...pumping and they recombine there. The injected charges are stored because of the reverse-biased junctions at the source and drain. The threshold-voltage change by the substrate bias is also investigated. If the silicon film is fully depleted under the gate, the threshold-voltage change does not occur. This condition is used to stabilize the high-speed operations of the SOS-MOS integrated circuits. A new memory cell consisting of only one transistor without a storage capacitor is realized utilizing the change of the floating-substrate potential by the charge pumping and the avalanche multiplication. The sensitivity of the memory cell is affected by the channel length of an SOS-MOS transistor. The memory storage time is obtained as 300 µs.
The efficacy of atipamezole as a medetomidine antagonist was evaluated in pigs. The atipamezole doses (intramuscularly) were 80, 160, 320 and 480 μg/kg of body weight, which were one, two, four and ...six times higher than the preceding medetomidine dose (80 μg/kg, intramuscularly). Atipamezole effectively reversed medetomidine-induced sedation, and the optimal action was seen at doses of 160 and 320 μg/kg. Recovery from sedation was quick and smooth, and adverse effects such as hyperactivity or tachycardia were minimal with either dose.
Cardiopulmonary effects of a combination of medetomidine and butorphanol were evaluated in atropinized pigs. This combination unchanged the cardiac output and significantly lowered the oxygen ...consumption compared with base-line values. Although some statistically significant changes were recorded, both medetomidine and butorphanol did not have a marked effect on the cardiopulmonary parameters in atropinized pigs. It was indicated that the administration of the combination of medetomidine and butorphanol is relatively safe in atropinized pigs.
Sedative and analgesic/anesthetic effects induced by a combination of medetomidine and midazolam were evaluated in pigs. This combination exerted a much more potent sedative effect than that induced ...by a medetomidine alone, even if the dose of medetomidine was reduced to one half, and even if the pigs were stimulated continuously during the induction phase. Pigs given this combination were induced to sedation smoothly and very quickly. During being sedated the arousal reaction induced by sensory stimuli were depressed profoundly and pigs could be placed in dorsal recumbency without any resistance. In addition, this combination produced moderate analgesic effect and apparent muscle relaxation. This potent effect induced by this combination seemed to be induced by a synergistic interaction between medetomidine and midazolam because the sedative effect achieved with this combination was much greater than that which could be expected from a simple additive response of both sedatives. This sedative combination may be a widely available and valuable for chemical restraint in pigs.
Plasma concentrations of four substances, a pyridine derivative (S7a), uric acid (UA), hippuric acid (HA) and kynurenic acid (KA), suspected as uremic toxins in dogs were determined in dogs with ...experimentally induced uremia by the ligations of renal arteries, spontaneous uremic dog patients and normal dogs. In experimentally induced uremic dogs, plasma concentrations of S7a, HA and KA showed continuous increase after the ligation of renal arteries together with a significant correlation to plasma creatinine concentration (Crc). Plasma UA concentration increased rapidly, but it showed a varying fluctuation without showing any correlation to Crc. Plasma concentrations of S7a, UA, HA and KA in spontaneous uremic dogs were almost within the ranges of those of experimentally induced uremic dogs.