Introduction
Venlafaxine is a serotonin-norepinephrine reuptake inhibitor and its extensive use for major depressive disorder and anxiety disorders. Although it has been reported that venlafaxine may ...have various side effects, as far as we know, spontaneous ejaculation(SE) has not been reported yet.
Objectives
We aim to describe this clinical case with venlafaxine-induced SE and to discuss the possible etiological factors.
Methods
Case report and literature review.
Results
A 53-year-old male with generalized anxiety disorder was initiated venlafaxine treatment with 75 mg/day. After two months patient’s complaints partially regressed and the dose of venlafaxine treatment was increased to 150 mg/day. 10 days after the dose increase, the patient applied with the complaint of SE 2-3 times a day. No urological etiology was found. During outpatient follow-ups, after the 5 days from reducing the daily dose to 75 mg/day, SE complaint completely regressed. After following couple of months, the patient by himself, increased the dose of venlafaxine to 150 mg/day without consulting a psychiatrist. Then SE recurred approximately 15 days later. Venlafaxine treatment dose was reduced again to 75 mg/day and urological complaints spontaneously regressed.
Conclusions
SE, a rare sexual side effect, represents ejaculation that occurs involuntarily and in the absence of any sexual stimuli. The possible mechanism of SE, detected as a side effect in our case, may be that increased adrenergic activity reduces ejaculatory latency and triggers spontaneous ejaculation. Antidepressant-associated sexual dysfunction could be a dose-dependent adverse event. Therefore, reducing the dosage of the treatment to a minimum effective dose could be an option.
Disclosure
No significant relationships.
Introduction
Bipolar disorder (BD) is a severe mood disorder, which is characterized by a cycling between the mania and major depression. The relationship between coping strategies and ...temperament-character traits in BD is unclear at this time.
Objectives
The aim of our study was to assess the relationship between strategies of coping stress and temperament-character traits in individuals with BD.
Methods
168 patients diagnosed with BD in full remission were included. All participants were diagnosed by an experienced consultant psychiatrist based on DSM-5 and were assessed with Young Mania Rating Scale (YMRS) for confirmation to remission. Sociodemographic datas of all participants was obtained and Temperament Evaluation of Memphis, Pisa, Paris and San Diego–Autoquestionnaire (TEMPS-A) and Coping with Stress Scale (CSS) were applied.
Results
75 patients (44.6%) were female and the mean age of the sample was 32.64±10.74 years, the mean duration of illness was 8.23±5.52 years and was found that the mean score of YMRS 5.35±4.19. It was presented Table 1 whether there was a statistically significant correlation between TEMPS-A and CSS subscales.
Conclusions
As coping strategies may be related to temperament-character traits and that could be important for psychological interventions in patients with BD.
Depressive
Hypertimic
Cyclothymic
Irritable
Anxious
Avoidance
-,067
-,159
,098
-,150
-,083
,485
,095
,305
,115
,387
Problem-focused coping strategies
-,268
-,153
,366
-,246
-,134
,004
,109
,000
-,009
,161
Social support
-,191
-,495
-,060
-,646
-,416
,044
,000
,535
,000
,000
Total
-,256
-,399
,149
-,370
-,324
,007
,000
,118
,000
,001
Disclosure
No significant relationships.
Introduction
Amisulpride is an atypical antipsychotic. Rabbit syndrome(RS) may be seen after antipsychotics use a few days or long‐term application. RS occurs after more frequent typical ...antipsychotics and also in rare cases atypical antipsychotics.Its characterized by the involuntary rhythmic movements of the lips however involves no tongue movements.
Objectives
Case report and reflection on its etiology
Methods
Case report and literature review
Results
A 28-year-old female with a diagnosis of schizophrenia applied with the complaints and symptoms of withdrawal, do not want to leave the house, physical anergy and avolition that started after stopped taking her medications. She was admitted to the psychiatry service and amisulpride treatment was started and was gradually increased to 800 mg/day. After 30 days of hospitalization, the patient was discharged with mild recovery. 14 days after the discharge, because of the abnormal involuntary movements in mouth, the patient applied. In clinical examination without tounge involvement, rhythmic motions were observed in the lips and jaw.Neurological examination, labrotory tests and cranial screening were all normal. She was evaluated by a private psychiatrist and was diagnosed with RS. Amisulpride treatment changed to olanzapine treatment with 15 mg/day. After two months, RS spontaneously regressed.
Conclusions
The resolution of the involuntary movements following discontinuation of amisulpride in our case, supported the diagnosis of RS. Although the mechanism by which RS emerges as a side‐effect of amisulpride is not fully understood, the drug’s high affinity for and selective binding to dopaminergic D2 and D3 receptors are thought to be responsible for this involuntary motion disorder.
Disclosure
No significant relationships.
Introduction
Generalized anxiety disorder (GAD) and Obsessive compulsive disorder (OCD) are common psychiatric disorders. Researchers studying the pathophysiology of these two disorders evaluated the ...effect of metacognition. However, there is no research examining the metacognition differences of these two psychiatric conditions.
Objectives
This study was performed to compare the metacognitions in OCD, GAD and healthy controls.
Methods
The sample of this study consisted of 158 GAD and 137 OCD patients aged 18-65 years who presented to outpatient psychiatry clinic and applied to the health committee 168 healthy controls without psychopathology. Sociodemographic data form, Meta-Cognitions Questionnaire-30 scale(MCQ-30), Beck Depression Inventory(BDI) and Beck Anxiety Inventory(BAI) were applied to the volunteer participants who met the criteria for participation in the study. The data obtained were evaluated statistically and subjected to statistical analysis.
Results
The mean age was 31.89 ± 10.86 years and was 60.5% (n = 208) women. There was statistical difference between marital status, occupation and income(p <0.05). In addition, there was a statistically significant difference between MCQ-30 total and subscales, BDI and BAI (p <0.001). According to the comparison of OCD and GAD patients, ’positive belief’, MCQ-30 total and BAI scores were found to be statistically different (p <0.05), ’Uncontrollability and danger’, ’Cognitive Confidence’, ’Beliefs about The Need to Control Thoughts’, ’Cognitive Self-Consciousness’, BDI there was no statistical difference between them (p> 0.05).
Conclusions
Our results are contributing to the understanding of the uncertainty of development and maintenance of OCD and GAD. Additionally, metacognitions could be important for the diagnosis and treatment of OCD and GAD.
Disclosure
No significant relationships.
Using multimodal conversation analysis this article examines embodied and tactile greetings in social interaction, documenting their change during the Covid‐19 pandemic. Recognizing social ...interaction as foundational for human sociality, we consider greetings as a crucial normative, organizational, and ritual practice for mutually engaging in intersubjective action. Analyses use video recordings made in Switzerland (featuring (Swiss‐)German and English as a lingua‐franca), focusing on embodied greetings of acquainted people in public spaces at the age of Covid19—a historical moment in which physical proximity and contact are targeted by official measures restricting social interactions. Studying a range of tactile embodied greetings, the paper shows how they change from routine greetings to hesitated, suspended yet still completed ones, and to projected but resisted and refused ones. Furthermore, it reveals some ‘new’ practices of greeting (elbow/feetbumps, hugs‐in‐the‐air) and their non‐straightforward and accountable character, as well as how they sediment and normalize during the pandemic.
Résumé
Dans le cadre de l'analyse conversationnelle multimodale, cet article se penche sur les salutations incarnées et tactiles dans l'interaction sociale, pour en documenter les changements observables durant la pandémie de Covid‐19. En reconnaissant que l'interaction sociale a un rôle fondateur pour la socialité humaine, nous considérons les salutations comme des pratiques normatives, organisationnelles, et rituelles cruciales pour s'engager mutuellement dans l'action intersubjective. Les analyses proposées reposent sur des enregistrements vidéo effectués en Suisse (langues impliquées: Allemand, Suisse‐Allemand, Anglais lingua franca), documentant des salutations incarnées entre interconnaissances dans les espaces publics à l’ère de la Covid‐19—un moment historique durant lequel la proximité physique et le contact corporel sont la cible de mesures officielles restreignant les interactions sociales. En étudiant une variété de salutations incarnées tactiles, cette étude montre comment elles changent, passant de salutations routinières à des salutations hésitantes, suspendues, tout en continuant à être complétées, aboutissant à des salutations projetées, mais faisant l'objet de résistance et de refus. Enfin, l’étude montre l’émergence de quelques "nouvelles" pratiques de salutations (avec les pieds, les coudes, et des embrassades en l'air), leur caractère initialement non‐évident, puis progressivement sédimenté et normalisé au fil de la pandémie.
Aims: The purpose of this study is to compare the stresses occurring in the peri-implant bones, implants, crowns, abutments, and screws after loading through finite element analysis by using the ...poly-ether-ether-ketone (PEEK) materials, which are alternative to titanium abutment and metal supported restorations and to try to reduce the level of neck resorption. Materials and Methods: In our study, three-dimensional modeling of 2 PEEK and titanium abutments, metal-ceramic, and monolithic PEEK upper central dental restorations were made on four titanium implants (Biohorizons® Implant Systems Ins., Birmingham, AL, USA) with diameters of 3.8 mm and 10.5 mm and four groups were obtained. Then, a stress analysis of the finite element was performed by applying a 178 N oblique force of 45° to the long axis of the tooth 2 mm below the incisal edge of the model's palatal surface. Results: It has been observed that the PEEK material reduces the stresses caused by the force applied on itself during all tests. In all groups, PEEK abutments and PEEK crowns have reduced stress on the abutment. The most significant difference is observed in the stresses on the crowns and screws. When the stresses on the crown are examined, the use of PEEK crown reduces the stresses on itself and the use of PEEK abutment increases the stresses on the crown. Conclusions: The stress on the implant system can be changed through the usage of different prosthetic materials.
•The case fatality rate of Influenza A(H3N2) was significantly higher than influenza A(H1N1).•Detection of the infection, allowing opportunity for the early use of antiviral agents, was found to be ...important for prevention of fatality.•The vaccination should be should be prioritized for at-risk groups.
Infection with the influenza A virus can cause severe disease and mortality. The effect of the different subtypes of influenza on morbidity and mortality is not yet known in Turkey. The aim of this study was to describe the predictors of fatality related to influenza A infection among hospitalized patients in Istanbul during the 2015–2016 influenza season, and to detail the differences between infections caused by H3N2 and H1N1.
This was a multicenter study performed by the Istanbul Respiratory Infections Study Group of The Turkish Society of Clinical Microbiology and Infectious Diseases (KLİMİK), among patients hospitalized for influenza in Istanbul during the 2015–2016 influenza season.
A total of 222 patients hospitalized with laboratory-confirmed influenza during the 2015–2016 season were included in the study, of whom 25 (11.2%) died. The fatality rate was significantly higher among patients older than 65 years of age and those with chronic heart and kidney diseases (p<0.001), chronic neurological diseases (p=0.009), and malignancies (p=0.021). Thrombocyte counts were lower in those who died than in those who survived (p<0.004). The median alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, creatinine phosphokinase, and C-reactive protein levels were higher among fatal cases. In the multivariate analysis for the prediction of fatality, being >65years old (odds ratio (OR) 6.9, 95% confidence interval (CI) 2.07–23.08, p=0.002), being infected with influenza A(H3N2) (OR 4.2, 95% CI 1.27–14.38, p=0.019), and a 1-day delay in antiviral use (OR 1.28, 95% CI 1.01–1.63, p=0.036) were found to be associated with an increased likelihood of fatality.
The case fatality rate of influenza A(H3N2) was significantly higher than that of influenza A(H1N1). Detection of the infection, allowing the opportunity for the early use of antiviral agents, was found to be important for the prevention of fatality. The vaccination should be prioritized for at-risk groups.
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