A massive hybrid array consists of multiple analog subarrays, with each subarray having its digital processing chain. It offers the potential advantage of balancing cost and performance for massive ...arrays and therefore serves as an attractive solution for future millimeter-wave (mm- Wave) cellular communications. On one hand, using beamforming analog subarrays such as phased arrays, the hybrid configuration can effectively collect or distribute signal energy in sparse mm-Wave channels. On the other hand, multiple digital chains in the configuration provide multiplexing capability and more beamforming flexibility to the system. In this article, we discuss several important issues and the state-of-the-art development for mm-Wave hybrid arrays, such as channel modeling, capacity characterization, applications of various smart antenna techniques for single-user and multiuser communications, and practical hardware design. We investigate how the hybrid array architecture and special mm-Wave channel property can be exploited to design suboptimal but practical massive antenna array schemes. We also compare two main types of hybrid arrays, interleaved and localized arrays, and recommend that the localized array is a better option in terms of overall performance and hardware feasibility.
Mobile network is evolving from a communication-only network towards one with joint communication and radar/radio sensing (JCAS) capabilities, that we call perceptive mobile network (PMN). Radio ...sensing here refers to information retrieval from received mobile signals for objects of interest in the environment surrounding the radio transceivers, and it may go beyond the functions of localization, tracking, and object recognition of traditional radar. In PMNs, JCAS integrates sensing into communications, sharing a majority of system modules and the same transmitted signals. The PMN is expected to provide a ubiquitous radio sensing platform and enable a vast number of novel smart applications, whilst providing non-compromised communications. In this paper, we present a broad picture of the motivation, methodologies, challenges, and research opportunities of realizing PMN, by providing a comprehensive survey for systems and technologies developed mainly in the last ten years. Beginning by reviewing the work on coexisting communication and radar systems, we highlight their limits on addressing the interference problem, and then introduce the JCAS technology. We then set up JCAS in the mobile network context and envisage its potential applications. We continue to provide a brief review of three types of JCAS systems, with particular attention to their differences in design philosophy. We then introduce a framework of PMN, including the system platform and infrastructure, three types of sensing operations, and signals usable for sensing. Subsequently, we discuss required system modifications to enable sensing on current communication-only infrastructure. Within the context of PMN, we review stimulating research problems and potential solutions, organized under nine topics: performance bounds, waveform optimization, antenna array design, clutter suppression, sensing parameter estimation, resolution of sensing ambiguity, pattern analysis, networked sensing under cellular topology, and sensing-assisted communications. We conclude the paper by listing key open research problems for the aforementioned topics and sharing some lessons that we have learned.
In this paper, fractional reverse polarity optical orthogonal frequency division multiplexing (FRPO-OFDM) is studied to enable dimming compatible visible light communications. The scheme combines a ...layered asymmetrically clipped optical OFDM (ACO-OFDM) sequence with an information-carrying brightness control sequence (BCS) in the form of M-ary pulse position modulation. We derive the expressions of the FRPO-OFDM signal and its achievable brightness level, and develop an effective detector which can recover information from both sequences based on maximum likelihood detection. We show that when the detector is to be implemented, the use of multi-layer ACO-OFDM imposes strong periodicity on the BCS, which leads to a trade-off between spectral efficiency and brightness resolution for dimming control. It is shown that high spectral efficiency can be achieved with practical dimming requirements. Simulation results show that the extra information carried by the BCS can be decoded with extremely low bit error rate and thus has negligible impacts on the demodulation of the ACO-OFDM signal, when the system nonlinearity is not dominating.
Urinary bladder cancer (UBC) patients at muscle invasive stage have poor clinical outcome, due to high propensity for metastasis. Cancer-associated fibroblasts (CAFs), one of the principal ...constituents of the tumor stroma, play an important role in tumor development. However, it is unclear whether CAFs from UBC induce cell invasion and which signaling pathway is involved. Herein, we found that conditional medium from UBC CAFs (CAF-CM) enhanced the invasion of UBC cells. CAF-CM induced the epithelial-mesenchymal transition (EMT) by regulating expression levels of EMT-associated markers in UBC cells. Higher concentration of TGFβ1 in CAF-CM, comparing with the CM from adjacent normal fibroblast, led to phosphorylation of Smad2 in UBC cells. Additionally, inhibition of TGFβ1 signaling decreased the EMT-associated gene expression, and cancer cell invasion. Interestingly, a long non-coding RNA, ZEB2NAT, was demonstrated to be essential for this TGFβ1-dependent process. ZEB2NAT depletion reversed CAF-CM-induced EMT and invasion of cancer cells, as well as reduced the ZEB2 protein level. Consistently, TGFβ1 mRNA expression is positively correlated with ZEB2NAT transcript and ZEB2 protein levels in human bladder cancer specimens. Our data revealed a novel mechanism that CAFs induces EMT and invasion of human UBC cells through the TGFβ1-ZEB2NAT-ZEB2 axis.
Future 5th generation networks are expected to enable three key services-enhanced mobile broadband, massive machine type communications and ultra-reliable and low latency communications (URLLC). As ...per the 3rd generation partnership project URLLC requirements, it is expected that the reliability of one transmission of a 32 byte packet will be at least 99.999% and the latency will be at most 1 ms. This unprecedented level of reliability and latency will yield various new applications, such as smart grids, industrial automation and intelligent transport systems. In this survey we present potential future URLLC applications, and summarize the corresponding reliability and latency requirements. We provide a comprehensive discussion on physical (PHY) and medium access control (MAC) layer techniques that enable URLLC, addressing both licensed and unlicensed bands. This paper evaluates the relevant PHY and MAC techniques for their ability to improve the reliability and reduce the latency. We identify that enabling long-term evolution to coexist in the unlicensed spectrum is also a potential enabler of URLLC in the unlicensed band, and provide numerical evaluations. Lastly, this paper discusses the potential future research directions and challenges in achieving the URLLC requirements.
High-capacity Ni-rich layered oxides are promising cathode materials for secondary lithium-based battery systems. However, their structural instability detrimentally affects the battery performance ...during cell cycling. Here, we report an Al/Zr co-doped single-crystalline LiNi
Co
Mn
O
(SNCM) cathode material to circumvent the instability issue. We found that soluble Al ions are adequately incorporated in the SNCM lattice while the less soluble Zr ions are prone to aggregate in the outer SNCM surface layer. The synergistic effect of Al/Zr co-doping in SNCM lattice improve the Li-ion mobility, relief the internal strain, and suppress the Li/Ni cation mixing upon cycling at high cut-off voltage. These features improve the cathode rate capability and structural stabilization during prolonged cell cycling. In particular, the Zr-rich surface enables the formation of stable cathode-electrolyte interphase, which prevent SNCM from unwanted reactions with the non-aqueous fluorinated liquid electrolyte solution and avoid Ni dissolution. To prove the practical application of the Al/Zr co-doped SNCM, we assembled a 10.8 Ah pouch cell (using a 100 μm thick Li metal anode) capable of delivering initial specific energy of 504.5 Wh kg
at 0.1 C and 25 °C.
A multitap adaptive filter with analog least mean-square (ALMS) loop is proposed in this paper for effective and low complexity self-interference cancellation implemented as part of the radio ...frequency frontend in a full duplex transceiver. Comprehensive analyses of the ALMS loop's behaviors at both micro and macroscales are presented for a wireless communication system with single carrier signaling. It is revealed that there is always an irreducible residual interference due to the cyclostationary property of the transmitted signal. The interference suppression ratio (ISR) lower bound is derived accordingly, which can be used as a design rule for determining the ALMS loop parameter. Stationary analysis shows that the convergence speed and achievable ISR of the ALMS loop are determined by the loop gain and the autocorrelation function of the transmitted signal. The interference channel modeling error with the adaptive filter also accounts for part of the residual interference power. These theoretical findings are verified by simulation and experimental results.
Joint communications and sensing (JCAS) has recently attracted extensive attention due to its potential in substantially improving the cost, energy and spectral efficiency of Internet of Things (IoT) ...systems that need both radio frequency functions. Given the wide applicability of orthogonal frequency division multiplexing (OFDM) in modern communications, OFDM sensing has become one of the major research topics of JCAS. To raise the awareness of some critical yet long-overlooked issues that restrict the OFDM sensing capability, a comprehensive overview of OFDM sensing is provided first in this paper, and then a tutorial on the issues is presented. Moreover, some recent research efforts for addressing the issues are reviewed, with interesting designs and results highlighted. In addition, the redundancy in OFDM sensing signals is unveiled, on which, a novel method is based and developed in order to remove the redundancy by introducing efficient signal decimation. Corroborated by analysis and simulation results, the new method further reduces the sensing complexity over one of the most efficient methods to date, with a minimal impact on the sensing performance.
Mechanical integrity issues such as particle cracking are considered one of the leading causes of structural deterioration and limited long-term cycle stability for Ni-rich cathode materials of ...Li-ion batteries. Indeed, the detrimental effects generated from the crack formation are not yet entirely addressed. Here, applying physicochemical and electrochemical ex situ and in situ characterizations, the effect of Co and Mn on the mechanical properties of the Ni-rich material are thoroughly investigated. As a result, we successfully mitigate the particle cracking issue in Ni-rich cathodes via rational concentration gradient design without sacrificing the electrode capacity. Our result reveals that the Co-enriched surface design in Ni-rich particles benefits from its low stiffness, which can effectively suppress the formation of particle cracking. Meanwhile, the Mn-enriched core limits internal expansion and improve structural integrity. The concentration gradient design also promotes morphological stability and cycling performances in Li metal coin cell configuration.
Biofilm accumulation on the polymethyl methacrylate (PMMA) restorations negatively affect the prognosis of the provisional restorations or the following treatment. This study developed a novel ...antibacterial PMMA resin containing low concentration of dimethylaminohexadecyl methacrylate (DMAHDM). Four resins were tested: (1) PMMA resin (Control), (2) 1.25% DMAHDM, (3) 2.5% DMAHDM, (4) 5% DMAHDM. Adding 1.25% DMAHDM into the PMMA resin did not influence the mechanical properties, degree of conversion, monomer releasing, and color stability of the specimens (
p
> 0.05). The incorporation of DMAHDM into PMMA resin could greatly prevent saliva-derived biofilms adhesion compared with the control group (
p
< 0.05). The metabolism level of saliva-derived biofilms on the 1.25%, 2.5%, and 5% DMAHDM resins were reduced by 20%, 54%, and 62%, respectively. And the mechanism of DMAHDM disturbing the integrity of bacterial cell walls was confirmed by flow cytometric analysis. Adding 1.25% and 2.5% DMAHDM did not compromise cytocompatibility of the modified resin (
p
> 0.05). Therefore, novel PMMA resin containing low concentration DMAHDM is promising as a future antimicrobial provisional restoration material for preventing microbial-induced complications in clinical settings.
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