In this paper, the Logistic regression model and χ
automatic interaction test were used to study the distribution, number, and correlation of common pathogenic bacteria of periodontal origin with ...combined periodontal and endodontic lesions by sample training, extracting variable characteristics, and then these variables were modeled as characteristic variables of the regression model to test whether the independent variables were significantly correlated with the dependent variables. It is also necessary to perform χ
automatic interaction test to compare with the normal distribution, and the results are merged into one group if they are the same and not incorporated into one group if they are different. After the merging was completed, the splitting was done. The study group had a detection rate of pathogenic bacteria of 50.70%, while the control group had a detection rate of 12.24%, according to the results. Campylobacter spp. was the main bacteria that infected periodontal pockets in the study group. And Clostridium spp. The root canal specimens were mainly from Corynebacterium spp. and Actinobacillus spp. There was a significant difference between the pathogenic species and the control group P<0.05. Campylobacter spp. was also a risk factor for co-morbidities (P=0.031). Intra-root canal tissue with its subgingival plaque pathogenic bacteria
,
(Ρ<0.05),
,
,
(Ρ<0.01) played a more important role in the development of pulpitis. Before and after clinical treatment, Pgi showed the most significant decrease in bacterial counts (t=2.759, P=0.022).
To investigate whether serum gonadal hormone levels are correlated to the development of facial synkinesis following Bell's palsy in postmenopausal women and man.
A total of 149 patients with Bell's ...palsy were enrolled in this study. All patients were instructed in standard treatment strategy by expert staff from their first visit. The degree of synkinesis was evaluated at 12 months after the onset of facial nerve palsy based on the synkinesis scores of Sunnybrook facial grading system. The patients were divided into two groups by gender.
Serum estradiol levels were significantly higher in patients with facial synkinesis than in patients without facial synkinesis following Bell's palsy in postmenopausal female. Male patients with facial synkinesis following Bell's palsy had a higher serum estradiol and testosterone levels. Baseline ENoG values (OR=11.144, 95% CI=1.001-124.126, p=0.008) and serum estradiol levels (OR=1.145, 95% CI=1.033-1.270, p=0.010) were the two independent predictors for facial synkinesis in postmenopausal female patients. Meanwhile, baseline ENoG values (OR=5.312, 95% CI=0.626-45.069, p=0.035), HbA1c values (OR=27.470, 95% CI=2.001-43.084, p=0.016), serum E2 levels (OR=1.298, 95% CI=1.092-1.542, p=0.003), and serum testosterone levels (OR=1.892, 95% CI=1.309-2.734, p=0.001) were the independent predictors for facial synkinesis in male patients.
Serum estradiol levels are associated with the development of facial synkinesis following Bell's palsy in postmenopausal female patients. Serum estradiol and testosterone levels are associated with the development of facial synkinesis following Bell's palsy in male patients. Serum gonadal hormone levels might be acted as potential biomarker for predicting facial synkinesis following Bell's palsy.
Graphite oxide (GO) supported CaO catalyst was prepared and successfully applied to the transesterification of soybean oil with methanol to produce biodiesel. The experimental results demonstrated ...that the GO supported CaO catalyst exhibits excellent catalytic activity and can be easily regenerated. The oxygen-containing groups (i.e., hydroxyl, epoxide groups and carboxyl groups) on the surface of GO support act as effective anchoring centers for the active phase. Display omitted
► Graphite oxide (GO) supported CaO catalyst was prepared. ► The catalyst was applied to the transesterification reaction to produce biodiesel. ► The catalyst exhibits excellent catalytic activity and easily to be regenerated. ► There are a large amount of oxygen-containing groups on the surface of GO. ► The oxygen-containing groups act as anchoring centers for the active phase.
Graphite oxide (GO) supported CaO catalysts were prepared and successfully applied to the transesterification of soybean oil with methanol. The supports and resultant catalysts were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), N2 adsorption, thermogravimetry (TG), X-ray photoelectron spectroscopy (XPS), temperature-programed desorption (TPD) and Fourier-transform infrared spectroscopy (FT-IR). The GO supported CaO catalysts exhibited excellent catalytic activity and were easily regenerated by simple heat-treatment. The oxygen-containing groups (i.e., hydroxyl, epoxide groups and carboxyl groups) present on the surface of GO likely act as anchoring centers for CaO. This work demonstrates that graphite oxide is an effective host material of catalytically active CaO nanoparticles for the transesterification of soybean oil with methanol to produce biodiesel.
Emerging evidence suggests that reactive oxygen species (ROS) play a significant role in the pathogenesis of peripheral nerve damage. Our previous study indicated that human herpesvirus 7 (HHV7) ...induces Bell’s palsy. However, the specific mechanism underlying the effects of ROS in HHV7 infection-induced facial nerve damage is unknown. In this study, we established a rat FN model by inoculating an HHV7 virus solution. The facial grading score and LuxolFastBlue (LFB) staining were used to assess the success of the model. Using mRNA-sequencing analysis, we found that the expression of Complex IV Subunit 4 Isoform 2 (Cox4i2) increased in infected Schwann cells (SCs). Cox4i2 was suggested to increase COX activity, thereby promoting ROS production. The changes in the endogenous oxidant and antioxidant system were assessed, and the results showed that oxidative stress increased after HHV7 infection
in vivo
and
in vitro
. However, we found that oxidative injury was relieved after the transfection of shCox4i2 in HHV7-treated SCs by evaluating cell death, cell proliferation, and the ROS level as well as the levels of malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione (GSH). Furthermore, we hypothesised that Cox4i2 loss would attenuate HHV7-induced ferroptosis and apoptosis, which are closely related to ROS in SCs. Our research illustrated that the knockdown of Cox4i2 suppresses HHV7-induced RSC96 cell ferroptosis as well as apoptosis via the ERK signalling pathway. Overall, several
in vitro
and
in vivo
methods were adopted in this study to reveal the new mechanism of ROS-induced and Cox4i2-mediated apoptosis and ferroptosis in HHV7 infected SCs.
Zhu, W., 2019. Study on the adjustment path of marine economic industrial structure in China's coastal provinces under the Belt and Road initiative. In: Li, L.; Wan, X.; and Huang, X. (eds.), Recent ...Developments in Practices and Research on Coastal Regions: Transportation, Environment and Economy. Journal of Coastal Research, Special Issue No. 98, pp. 219–222. Coconut Creek (Florida), ISSN 0749-0208. The implementation of the Belt and Road initiative is an important strategic support for building a new regional opening pattern. It has important strategic significance for cultivating new industries along the line and developing new space for the development of the marine economy. All relevant coastal cities should actively use the development strategy of this country in the new era and actively promote the upgrading and transformation of the marine economic structure. This paper introduces the opportunities brought by the Belt and Road initiative to the marine industry of China's coastal provinces and analyzes the main problems existing in the development of marine economic industry in China's coastal provinces. Then, the North Bay is taken as an example to propose the marine industry selection and system construction. Finally, it expounds the path of the adjustment of the marine economic industrial structure of China's coastal provinces under the Belt and Road initiative. It is expected to promote the cooperation and exchange of higher level marine economy among the countries and regions along the coastal cities of China and the Maritime Silk Road and promote the development of marine economy in China's coastal cities.
•Zirconia supported POM composites were synthesized by sol–gel technology.•The POM clusters are highly dispersed in the composites.•Strong interaction is built between POM units and ZrO2 ...framework.•The composites show high catalytic activity in cyclohexene oxidation with H2O2.•These catalysts are truly heterogeneous in nature, and easily recycled.
The Keggin-type polyoxometalates (POMs) including phosphotungstate and Ti-substituted phosphotungstates were supported on zirconia (ZrO2) matrix by a surfactant-assisted sol–gel copolymerization technique. The resultant ZrO2 supported POMs composite materials (ZrO2–POMs) were characterized by X-ray power diffraction, transmission electron microscopy, Fourier transform infrared spectra, diffuse reflectance ultraviolet–visible spectra, thermogravimetry-differential scanning calorimetry analysis, and 31P magic angle spinning (MAS) nuclear magnetic resonance (NMR) analysis. The results showed that the ZrO2–POMs materials have worm-like disordered mesoporous, and the primary structure of POMs is preserved after the formation of the composite materials. All the ZrO2–POMs materials are catalytically active for the H2O2-mediated oxidation of cyclohexene with relatively high selectivity to allylic oxidation products. Moreover, these materials exhibit high stability against leaching of active species, and can be easily recycled without obvious loss of activity and selectivity. The existence of relatively strong interaction between the POM units and the ZrO2 framework should play important role in fabricating the stable heterogeneous ZrO2–POMs catalysts.
Background: Most cases of hemifacial spasm result from mechanical compression at the root exit zone of the facial nerve by vascular loops, and only a few cases are caused by vestibular schwannoma. ...Case presentation: We report a case of symptomatic hemifacial spasm induced by a small vestibular schwannoma that was totally resected. A 64-year-old man was admitted to our department with a 14-month history of symptomatic right-sided hemifacial spasm. During the process of microvascular decompression, no definite vessel was found to compress the facial nerve. By further exploration of regions other than root exit zone, a small vestibular schwannoma compressing the internal auditory canal portion of facial nerve from the ventral side was discovered. Resection of the tumor was then conducted. The symptoms of hemifacial spasm disappeared immediately after surgery. Conclusions: We should be aware that magnetic resonance imaging is not always precise and perhaps misses some miniature lesions due to present image technique limitations. A small vestibular schwannoma might be the reason for HFS, although preoperative magnetic resonance tomography angiography showed possible vascular compression at the facial nerve root. More importantly, a full-length exploration of the facial nerve is in urgent need to find potential compression while performing microvascular decompression for HFS patients.
Glioma is the most common intracranial malignant tumor. Low-grade gliomas (LGG) occupy almost 80% in all of the gliomas. The prognosis of LGG in children is much better than in adult, however, the ...molecular mechanism is still unclear. In our investigation, it was first found that the level of soluble IL1RAP (sIL1RAP) was significantly higher in the LGG from children than that from adult. We also revealed that sIL1RAP could induce the apoptosis of U251. In cells with overexpression of sIL-1RAP, the cell proliferation promoted by IL-1 was significantly inhibited. These decreased tumor growth ability and better prognosis of low-grade gliomas in children patients than that in adult patients. The expression level of sIL1RAP may become one of the potential indexes for determining the prognosis of low-grade gliomas.
The Prins condensation of isobutylene with formaldehyde over scillica-supported silicotungstic acid catalysts has been investigated. The catalysts were characterized via XRD, FTIR, Py-IR, NH
3
-TPD ...and TG–DSC techniques. It was found that the catalyst with 5 wt% silicotungstic acids loading exhibited the best isobutene conversion and isoprene selectivity, and excessive silicotungstic acid was not conducive to improve the catalytic performance. It was proposed that the concentration and strength of acid sites could affect the catalytic properties. An appropriate amount of weak Lewis acid sites were the active site for the condensation of isobutene with formaldehyde, and the medium-strong acid sites could cause the side reactions and coke deposits.
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