•A plant-wide model is presented for continuous biomanufacturing benchmarking.•The model includes a tailored control strategy for dynamic simulation performance.•Realistic sensors and actuators ...consider measurement's noise and lag time.•Case study framework and examples are provided for user guidance.
The pharmaceutical industry's shift towards biological therapeutics has led to a transition from conventional batch production to continuous manufacturing. This change highlights the crucial need for effective process monitoring and control strategies to ensure consistent product quality and stability. Open-source benchmark simulation models have become essential tools for refining these processes, offering a platform for testing research hypotheses. This study uses the production of Lovastatin as a case study for continuous biopharmaceutical production. A comprehensive dynamic model covering upstream and downstream components provides an integrated perspective of the production process. The study introduces a basic control system emphasizing realistic sensor and actuator integration to enhance simulation accuracy. It assesses the benchmark through open-loop and closed-loop simulations, offering an in-depth analysis of the KTB1 model's dynamic response and functionality. KTB1 represents a model-driven decision support tool that enables the evaluation of monitoring strategies, process design, process optimization, and control for biomanufacturing.
Overall harmonic distortion and losses will grow during an energy conversion process, while power stability will be reduced. Multilevel inverter technologies have recently become very popular as ...low-cost alternatives for a variety of industrial purposes. The design's minimal benefits include reduced component losses, decreased switching and conduction losses, along with enhanced output voltage and current waveforms. Also, a reduction of the harmonic components of the current and output voltage of the inverter are the most important requirements in multilevel inverters. A seven-level inverter design is presented in this paper that is simulated using MATLAB/Simulink. The inverter converts the DC voltage from three photovoltaic (PV) systems into AC voltage at seven levels. During an outage of one of the PV systems, the inverter will make a switching reduction and supply the AC voltage as a five-level inverter. The inverter’s total harmonic distortion (THD) when it performs as a five-level or seven-level inverter is 4.19% or 1.13% respectively. The modulation technique used is phase disposition via four carriers and a single reference signal at the fundamental frequency.
This paper proposes the brushless direct current (BLDC) motor with high power density and high efficiency characteristics may be used to propulsion framework for electric vehicle. The progressive ...model for BLDC motor under rotor flux linkage route reference frame might have been providing. Here we analyzed the chart of ann vector and principal of ann control strategies and proposing the ann based reactive power with BLDC motor. To make ann based framework on active power, torque ripple, dc voltage, power factors can be used BLDC motor was designed. After designed simulation results was test the validity of field weakening based on reactive power with BLDC for electric vehicle application. In this research work will introduced artificial neural network (ANN) for non electrical input used. To control the BLDC motor speed it can using pulse width modulated control of the voltage source inverter (VLSI) using DC link voltage (Vdc) controller. To perform electronic commutation by hall signal sensing they are using PWM signal, to generate PWM signal inbuilt encoder can be used in this circuit. Analyze the BLDC motor performance driving propulsion framework is carried out under the MATLAB/Simulink software’s and efficiency of whole frame work is calculated under various source conditions
Energy consumption has always been considered one of the major issues in the six Gulf Cooperation Council (GCC) countries. Therefore, the predicted energy consumption can respond based on several ...factors and conditions, where which will help in response to plan saving energy for the future. The significant contribution of the present study is the development of software merging the Petri-Nets and ANFIS to become a comprehensive model to find the maximum annual load demand estimation of the GCC countries based on the historical data of the countries. The ANFIS-Petri Nets have expected modeling to represent knowledge and help in rule-based expert systems. The data has several parameters/conditions (factors), where these factors are temperature, humidity, GDP, pressure, and energy consumption. The results lead to a fast and accurate figure have developed an energy estimated system that works by tracking, analyzing, and controlling conditions of the energy system. The Petri-Nets ANFIS developed technique targeting the estimated maximum annual energy consumption believes that obtaining the values is satisfactory for the future of GCC states. In addition, the developed and obtained models have great application for the GCC countries. This might help to develop the models of other countries.
Microgrids are small-scale power networks that include renewable energy sources, load, energy storage systems, and energy management systems (EMS). Lithium-ion batteries are the most used battery for ...energy storage in microgrids due to their advantages over other types of batteries. However, to protect the battery from the explosion and to manage to charge and discharge based on state-of-charge (SoC) value, this type of battery requires the use of an energy management system. The main objective of this paper is to propose an intelligent control strategy for energy management in the microgrid to control the charge and discharge of Li-ion batteries to stabilize the system and reduce the cost of electricity due to the high cost of grid electricity. The proposed technique is based on a fuzzy logic controller (FLC) for voltage control. The FLC is based on the measured voltage of the direct current (DC) bus and the fixed reference voltage to generate buck/boost converter signal control. The proposed technique has been simulated and tested using MATLAB/Simulink software which illustrates the tracking of desired power and DC bus voltage regulation. The simulation results confirm that the proposed systems can diminish the deviations of the system's voltage.
The heating oven is a basic and easy-to-build model for exchanging and heating various types of engine equipment that require the use of thermal energy. In addition, this is also a model used in ...research in laboratories using basic algorithms such as PID. However, in the past, to control the heating oven, we needed to use expensive PLCs and microprocessors, and it was difficult to write programs. Recently, there are many studies that have succeeded in getting the program into the Arduino using C. Programming and this method requires the operator to have a lot of programming knowledge. To solve this problem, we have implemented and succeeded in using Matlab/Simulink with embedded Arduino and real model.
•A simulation model is developed to optimize the resistance value of the heating element for a photovoltaic (PV) direct-coupled water heater.•The simulation model is experimentally validated. The ...correlation coefficient (R2) ranges from 98.75% to 99.89%.•When the incident solar irradiance increases the optimal resistance value decreases, and vice versa.•The annual solar fraction of a direct-coupled PV water heater ranges from 41% in Montreal, Canada, to 73% in Fez, Morocco.•The use of an MPPT controller increases the PV energy production by 29% on average.
In the last few years, the price of photovoltaic (PV) modules has decreased significantly. As a result, solar PV has become an interesting option for water heating. In a direct-coupled PV water heater (DPVWH) system, the PV array is directly connected to the heating element. Therefore, the optimization of the heating element resistance value is an essential step to design a DPVWH system. This research aims to optimize the resistance value of the heating element for different climatic conditions (Montreal and Bagotville in Canada, and Fez in Morocco). Simulation models were developed using MATLAB/Simulink and TRNSYS software to evaluate the performance of a PV system directly connected with the heating element over a one-year period. This simulation model was validated with an experimental setup. The coefficient of determination (R2) ranges from 98.75% to 99.89%. The results of the experimental optimization indicate that in areas with high incident solar irradiation, the optimal resistance value is low, while the opposite is true for areas with lower solar irradiation. Furthermore, it is found that a direct-coupled PV water heater with a capacity of 3000 Wp achieves an average annual solar fraction of 41% in Montreal, and 73% in Fez. Additionally, the simulation results show that the use of an MPPT (Maximum Power Point Tracking) controller could increase the PV energy production by 29% in average. However, a direct-coupled PV solar water heater system is recommended for a remote and cold region, due to its robustness, its low operating cost, and its simplicity.
Endüstri 4.0 başlığı altında gözlemlenen gelişmeler üretim frezeleme sürecinde veri toplama ve analizi uygulamalarını mümkün kılmıştır. Bu çalışmaların uygulanabilmesi için yazılımların ...geliştirilmesi gerekmektedir ve bu yazılımların geliştirilmesi için test yapılması masraflı ve zahmetlidir. Bu çalışmada frezeleme işleminin dinamik modellenmesi Matlab Simulink ortamında gerçekleştirilmiştir. Frezeleme sürecinin dinamiğini açıklamak adına literatür dikkatli bir şekilde taranarak amaca uygun modeller, hesaplamalar seçilmiş ve kapalı çevrim takım parça titreşim modeliyle birleştirilmiştir. Kuvvet modeli olarak doğrusal kuvvet modeli ve Martellotti talaş kalınlığı seçilmiş ve sistem referansı olarak deney yapılacak olan freze tezgahında çekiç testleriyle elde edilen FTF’lerin modal analizi kullanılıp transfer fonksiyonları elde edilmiştir. Parça malzemesi olarak AL7075 seçilmiştir ve kuvvet katsayıları deneysel olarak başka bir çalışmada bulunmuştur. Kesim testi yapılmış ve ivmeler ölçülüp aynı kesim parametreleri ile yapılan simülasyonla karşılaştırılmış ve model doğrulanmıştır. Geliştirilen model ivmelerin genliklerini doğru tahmin etmektedir.