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hits: 158
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  • Single-cell secretion analy... Single-cell secretion analysis reveals a dual role for IL-10 in restraining and resolving the TLR4-induced inflammatory response
    Alexander, Amanda F.; Kelsey, Ilana; Forbes, Hannah ... Cell reports, 09/2021, Volume: 36, Issue: 12
    Journal Article
    Peer reviewed
    Open access

    Following Toll-like receptor 4 (TLR4) stimulation of macrophages, negative feedback mediated by the anti-inflammatory cytokine interleukin-10 (IL-10) limits the inflammatory response. However, ...
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12.
  • Highly Multiplexed Single‐C... Highly Multiplexed Single‐Cell Protein Profiling with Large‐Scale Convertible DNA‐Antibody Barcoded Arrays
    Zhao, Peng; Bhowmick, Sirsendu; Yu, Jianchao ... Advanced science, September 2018, Volume: 5, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Highly multiplexed detection of proteins secreted by single cells is always challenging. Herein, a multiplexed in situ tagging technique based on single‐stranded DNA encoded microbead arrays and ...
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  • Optically Manipulated Micro... Optically Manipulated Microtools to Measure Adhesion of the Nanoparticle-Targeting Ligand Glutathione to Brain Endothelial Cells
    Fekete, Tamás; Mészáros, Mária; Szegletes, Zsolt ... ACS applied materials & interfaces, 08/2021, Volume: 13, Issue: 33
    Journal Article
    Peer reviewed

    Targeting nanoparticles as drug delivery platforms is crucial to facilitate their cellular entry. Docking of nanoparticles by targeting ligands on cell membranes is the first step for the initiation ...
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  • Fertilisation with potato s... Fertilisation with potato starch wastewater effect on the growth of Scots pine (Pinus sylvestris L.) forest in Poland
    Waszak, Nella; Campelo, Filipe; Robertson, Iain ... Trees, Forests and People (Online), March 2024, 2024-03-00, 2024-03-01, Volume: 15
    Journal Article
    Peer reviewed
    Open access

    •High nitrogen concentrations have a negative effect on radial growth.•Overfertilized trees produce tracheids with thinner cell walls.•Wood structure in over-fertilized trees can affect water ...
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  • Protein-binding dynamics im... Protein-binding dynamics imaged in a living cell
    Phillip, Yael; Kiss, Vladimir; Schreiber, Gideon Proceedings of the National Academy of Sciences - PNAS, 01/2012, Volume: 109, Issue: 5
    Journal Article
    Peer reviewed
    Open access

    Historically, rate constants were determined in vitro and it was unknown whether they were valid for in vivo biological processes. Here, we bridge this gap by measuring binding dynamics between a ...
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  • Microfluidics for Single-Cell Study of Antibiotic Tolerance and Persistence Induced by Nutrient Limitation
    Moreno-Gámez, Stefany; Dal Co, Alma; van Vliet, Simon ... Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2357
    Journal Article

    Nutrient limitation is one of the most common triggers of antibiotic tolerance and persistence. Here, we present two microfluidic setups to study how spatial and temporal variation in nutrient ...
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17.
  • Viscoelastic properties of ... Viscoelastic properties of cell walls of single living plant cells determined by dynamic nanoindentation
    Hayot, Céline M.; Forouzesh, Elham; Goel, Ashwani ... Journal of experimental botany, 04/2012, Volume: 63, Issue: 7
    Journal Article
    Peer reviewed
    Open access

    Plant development results from controlled cell divisions, structural modifications, and reorganizations of the cell wall. Thereby, regulation of cell wall behaviour takes place at multiple length ...
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  • Cell Membrane Proteins Modu... Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation
    Roxbury, Daniel; Jena, Prakrit V; Shamay, Yosi ... ACS nano, 01/2016, Volume: 10, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Cell adhesion is a protein-mediated process intrinsic to most living organisms. Dysfunction in cell adhesion processes is implicated in various diseases, including thrombosis and metastatic cancers. ...
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  • Using singular value decomp... Using singular value decomposition to characterize protein-protein interactions by in-cell NMR spectroscopy
    Majumder, Subhabrata; DeMott, Christopher M; Burz, David S ... ChemBioChem, May 5, 2014, Volume: 15, Issue: 7
    Journal Article
    Peer reviewed
    Open access

    Distinct differences between how model proteins interact in-cell and in vitro suggest that the cytosol might have a profound effect in modulating protein-protein and/or protein-ligand interactions ...
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  • Systematic Investigation of... Systematic Investigation of Transcription Factor Activity in the Context of Chromatin Using Massively Parallel Binding and Expression Assays
    Levo, Michal; Avnit-Sagi, Tali; Lotan-Pompan, Maya ... Molecular cell, 02/2017, Volume: 65, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Precise gene expression patterns are established by transcription factor (TFs) binding to regulatory sequences. While these events occur in the context of chromatin, our understanding of how ...
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