In recent years, the fields of reconfigurable manufacturing systems, holonic manufacturing systems, and multiagent systems have made technological advances to support the ready reconfiguration of ...automated manufacturing systems. While these technological advances have demonstrated robust operation and been qualitatively successful in achieving reconfigurability, their ultimate industrial adoption remains limited. Among the barriers to adoption has been the relative absence of formal and quantitative multiagent system design methodologies based on reconfigurability measurement. Hence, it is not clear that the degree to which these designs have achieved their intended level of reconfigurability, which systems are indeed quantitatively more reconfigurable, and how these designs may overcome their design limitations to achieve greater reconfigurability in subsequent design iterations. To our knowledge, this paper is the first multiagent system reference architecture for reconfigurable manufacturing systems driven by a quantitative and formal design approach. It is rooted in an established engineering design methodology called axiomatic design for large flexible engineering systems and draws upon design principles distilled from prior works on reconfigurability measurement. The resulting architecture is written in terms of the mathematical description used in reconfigurability measurement, which straightforwardly allows instantiation for system-specific application.
The evolution of manufacturing systems, influenced by changes along four axes - products, technology, business strategies and production paradigms - is presented. Adoption of human-centric decision ...making in meshed collaboration with intelligent systems is examined. Implications and preparedness for the shift towards more responsive, intelligent adaptive systems are reviewed. Research and industrial use cases are presented. A vision for the new future Adaptive Cognitive Manufacturing System (ACMS) paradigm and its characteristics, drivers and enablers are articulated highlighting the digital and cognitive transformations. Perspectives and insights are offered for future research, education, and work to realize the evolution of manufacturing systems.
Recent trends in biocatalysis Yi, Dong; Bayer, Thomas; Badenhorst, Christoffel P S ...
Chemical Society reviews,
07/2021, Volume:
50, Issue:
14
Journal Article
Peer reviewed
Open access
Biocatalysis has undergone revolutionary progress in the past century. Benefited by the integration of multidisciplinary technologies, natural enzymatic reactions are constantly being explored. ...Protein engineering gives birth to robust biocatalysts that are widely used in industrial production. These research achievements have gradually constructed a network containing natural enzymatic synthesis pathways and artificially designed enzymatic cascades. Nowadays, the development of artificial intelligence, automation, and ultra-high-throughput technology provides infinite possibilities for the discovery of novel enzymes, enzymatic mechanisms and enzymatic cascades, and gradually complements the lack of remaining key steps in the pathway design of enzymatic total synthesis. Therefore, the research of biocatalysis is gradually moving towards the era of novel technology integration, intelligent manufacturing and enzymatic total synthesis.
Rapid and cost-effective scalability of the throughput of manufacturing systems is an invaluable feature for the management of manufacturing enterprises. System design for scalability allows the ...enterprise to build a manufacturing system to supply the current demand, and upgrade its throughput in the future, in a cost-effective manner, to meet possible higher market demand in a timely manner. To possess this capability, the manufacturing system must be designed at the outset for future expansions in its throughput to enable growths in supply exactly when needed by the market. A mathematical method that maximises the system throughput after reconfiguration is proposed, and an industrial case is presented to validate the method. The paper offers a set of principles for system design for scalability to guide designers of modern manufacturing systems.
Abstract Current engineering production is characterised by rapid changes. These changes arise due to the shortening of product life cycles. Manufacturers are forced to introduce upgraded products at ...shorter intervals based on customer requirements. In this paper, we focus on the possibilities of production upgrading by using a group technology in the flexible manufacturing system. The production capabilities of one of the production machines in the manufacturing system will be analysed. This production machine is a lathe that produces one of the essential parts of a finished product. Determine what variations of this part can be produced without changing the physical configuration of the machine.
•Designed a Graduation-inspired assembly system for fixed-position layout.•Unified digital representations with appropriate sets of information at object, product and system level are ...developed.•IoT-enabled solutions are proposed to achieve real-time synchronization between physical space and digital space.•Developed cloud-based services with real-time ticket pool management mechanisms for facilitating decision-making and daily operations.
The layout of fixed-position assembly islands is widely used in the heavy equipment industry, where the product remains at one assembly island for its entire assembly period, while required workers, equipment, and materials are moved to the island according to the assembly plan. Such layout is not only suitable for producing bulky or fragile products, but also offers considerable flexibility and competitive operational efficiency for products with medium variety and volumes. However, due to inherent complexity of the product, sophisticated assembly operations heavily rely on skilled operators, and the complexity and uncertainty are high and amplified by such massive manual interventions as well as the unique routing patterns of the fixed-position assembly process. Aiming at reducing the complexity and uncertainty, this paper introduces a digital twin-enabled Graduation Intelligent Manufacturing System (DT-GiMS) for fixed-position assembly islands. Inspired by the success of graduation ceremony, an assembly system-Graduation Manufacturing System (GMS) is proposed for fixed-position assembly islands, in which job tickets, setup tickets, operation tickets, and logistics tickets are designed to organize the production activities. Following the concept of digital twin, unified digital representations with appropriate sets of information are created at object level, product level, and system level, respectively. Through Internet of Things (IoT), smart gateway, Web 3D and industrial wearable technologies, vital information including identity, status, geometric model, and production process can be captured and mapped in physical space, and converged and synchronized with their digital representations in twin (cloud) space on a real-time basis. The overall framework of DT-GiMS is presented with physical layer, digital layer, and service layer. Real-time convergence and synchronization among them ensure that right resources are allocated and utilized to the right activities at the right time with enhanced visibility. Considering customer demand and production capacity constraints, real-time ticket pool management mechanisms are proposed to manage production activities in a near-optimal way under DT-GiMS. With the support of cloud-based services provided in service layer in DT-GiMS, managers could easily make production decisions, and onsite operators could efficiently complete their daily tasks with nearly error-free operations with enhanced visibility. A demonstrative case is carried out to verify the effectiveness of the proposed concept and approach.
Based on research into the applications of artificial intelligence (AI) technology in the manufacturing industry in recent years, we analyze the rapid development of core technologies in the new era ...of'Internet plus AI', which is triggering a great change in the models, means, and ecosystems of the manufacturing industry, as well as in the development of AI. We then propose new models, means, and forms of intelligent manufacturing, intelligent manufacturing system architecture, and intelligent man- ufactudng technology system, based on the integration of AI technology with information communications, manufacturing, and related product technology. Moreover, from the perspectives of intelligent manufacturing application technology, industry, and application demonstration, the current development in intelligent manufacturing is discussed. Finally, suggestions for the application of AI in intelligent manufacturing in China are presented.
The focus of this paper is on the use of the Manufacturing System Design Decomposition (MSDD) to make effective cost and production system design decisions. A comparative study is conducted to ...illustrate how and why the total cost is reduced when the functional requirements defined by the MSDD are achieved. The ultimate goal of this research was to advance manufacturing and production system development to being guided by engineering science and design rather than the common practice of duplicating another person's or entity's notion of the best physical implementation.
The complexity in the collaboration between humans and robots in smart manufacturing remains a significant challenge. This paper introduces an LLM-based manufacturing execution system enhancing ...Human-Robot Collaboration (HRC) in smart manufacturing. By leveraging Large Language Models (LLMs), the system provides a natural language interface for operators, integrates with Digital Twins for real-time data, and employs behavior-based control for robots. This integration facilitates intuitive interactions and rapid system programming, addressing communication complexities in HRC. The effectiveness of this approach is validated through two HRC assembly case studies, demonstrating significant improvements in collaboration and efficiency.
•Reconfiguring nearby FMC of the failure node can increase the resilience of FMS.•Increasing the storage capacity can further improve the resilience of FMS.•Two theorems can significantly reduce the ...cardinality of the strategy set.
In the past few years, due to various man-made and natural disasters such as COVID-19, the manufacturing industry worldwide has undergone significant changes. To counter and prevent the losses, it is important to consider the resilience of the manufacturing systems. In this paper, a new method for designing resilient Flexible Manufacturing System (FMS) is presented. The FMS is modeled by a directional network. The method consists of two types of strategies: one is to use Flexible Manufacturing Cells (FMC) and reconfigure route (Strategy A) and the other is to use a combination of FMC and its extended storage capacity (Strategy B). The resilience is measured by the Production Lost and the Investment Return. Using the Monte Carlo Simulation, FMS can be investigated under various failure conditions. For complex FMS, the size of the strategy set is very large. Thus, two theorems are proposed to reduce the size without effecting the optimal solution. A demonstration example with 33 nodes fabricating 5 kinds of products is presented. It shows that compared to simply waiting for fixing failure, the use of Strategy A and Strategy B will result in more than 10% increase in Investment Return.