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  • NRF2 and the Hallmarks of C... NRF2 and the Hallmarks of Cancer
    Rojo de la Vega, Montserrat; Chapman, Eli; Zhang, Donna D. Cancer cell, 07/2018, Volume: 34, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    The transcription factor NRF2 is the master regulator of the cellular antioxidant response. Though recognized originally as a target of chemopreventive compounds that help prevent cancer and other ...
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43.
  • From Melanocytes to Melanoma From Melanocytes to Melanoma
    Hearing, Vincent J; Leong, Stanley P. L 2006, 2005
    eBook

    Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, ...
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44.
  • Agrobacterium T‐DNA integra... Agrobacterium T‐DNA integration in somatic cells does not require the activity of DNA polymerase θ
    Nishizawa‐Yokoi, Ayako; Saika, Hiroaki; Hara, Naho ... The New phytologist, March 2021, 2021-03-00, 20210301, Volume: 229, Issue: 5
    Journal Article
    Peer reviewed
    Open access

    Summary Integration of Agrobacterium tumefaciens transferred DNA (T‐DNA) into the plant genome is the last step required for stable plant genetic transformation. The mechanism of T‐DNA integration ...
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45.
  • Transboundary Cooperation a... Transboundary Cooperation and Global Governance for Inclusive Sustainable Development
    05/2022
    eBook
    Open access

    This book gathers renowned researchers and policymakers from all continents who have accompanied Dirk Messner’s professional life in science and policy advice. Their articles and essays cover topics ...
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46.
  • Transformation-induced plas... Transformation-induced plasticity (TRIP) in advanced steels: A review
    Soleimani, Maryam; Kalhor, Alireza; Mirzadeh, Hamed Materials science & engineering. A, Structural materials : properties, microstructure and processing, 09/2020, Volume: 795
    Journal Article
    Peer reviewed

    The transformation-induced plasticity (TRIP) in advanced high-strength steels (AHSS) is reviewed, where the main concepts and the recent progress in the processing and properties of AHSS are ...
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  • Role of oxidative stress in... Role of oxidative stress in cadmium toxicity and carcinogenesis
    Liu, Jie; Qu, Wei; Kadiiska, Maria B. Toxicology and applied pharmacology, 08/2009, Volume: 238, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Cadmium (Cd) is a toxic metal, targeting the lung, liver, kidney, and testes following acute intoxication, and causing nephrotoxicity, immunotoxicity, osteotoxicity and tumors after prolonged ...
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  • RET rearrangements are acti... RET rearrangements are actionable alterations in breast cancer
    Paratala, Bhavna S; Chung, Jon H; Williams, Casey B ... Nature communications, 11/2018, Volume: 9, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Fusions involving the oncogenic gene RET have been observed in thyroid and lung cancers. Here we report RET gene alterations, including amplification, missense mutations, known fusions, novel ...
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49.
  • Ultraviolet radiation shape... Ultraviolet radiation shapes dendritic cell leukaemia transformation in the skin
    Griffin, Gabriel K; Booth, Christopher A G; Togami, Katsuhiro ... Nature (London), 06/2023, Volume: 618, Issue: 7966
    Journal Article
    Peer reviewed
    Open access

    Tumours most often arise from progression of precursor clones within a single anatomical niche. In the bone marrow, clonal progenitors can undergo malignant transformation to acute leukaemia, or ...
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  • Phosphoglycerate dehydrogen... Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
    Locasale, Jason W; Cantley, Lewis C; Vander Heiden, Matthew G ... Nature genetics, 09/2011, Volume: 43, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Most tumors exhibit increased glucose metabolism to lactate, however, the extent to which glucose-derived metabolic fluxes are used for alternative processes is poorly understood. Using a ...
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