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  • Characterization of the interaction between the Sec61 translocon complex and ppαF using optical tweezers
    Robeson, Luka; Casanova-Morales, Nathalie; Burgos-Bravo, Francesca ... Protein science 33, Issue: 6
    Journal Article
    Peer reviewed

    The Sec61 translocon allows the translocation of secretory preproteins from the cytosol to the endoplasmic reticulum lumen during polypeptide biosynthesis. These proteins possess an N-terminal signal ...
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  • Best practices, errors, and... Best practices, errors, and perspectives of half a century of plant translocation in Italy
    D'Agostino, Martina; Cao Pinna, Luigi; Carboni, Marta ... Conservation biology, August 2024, Volume: 38, Issue: 4
    Journal Article
    Peer reviewed

    Conservation translocations are becoming common conservation practice, so there is an increasing need to understand the drivers of plant translocation performance through reviews of cases at global ...
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  • Type IV secretion systems: ... Type IV secretion systems: Advances in structure, function, and activation
    Costa, Tiago R. D.; Harb, Laith; Khara, Pratick ... Molecular microbiology, March 2021, Volume: 115, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Bacterial type IV secretion systems (T4SSs) are a functionally diverse translocation superfamily. They consist mainly of two large subfamilies: (i) conjugation systems that mediate interbacterial DNA ...
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  • The MLL recombinome of acute leukemias in 2017
    Meyer, C; Burmeister, T; Gröger, D ... Leukemia, 02/2018, Volume: 32, Issue: 2
    Journal Article
    Peer reviewed
    Open access

    Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant, pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained from 2345 acute leukemia ...
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  • Sec61 blockade by mycolacto... Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export
    Grotzke, Jeff E; Kozik, Patrycja; Morel, Jean-David ... Proceedings of the National Academy of Sciences - PNAS, 07/2017, Volume: 114, Issue: 29
    Journal Article
    Peer reviewed
    Open access

    Although antigen cross-presentation in dendritic cells (DCs) is critical to the initiation of most cytotoxic immune responses, the intracellular mechanisms and traffic pathways involved are still ...
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  • Membrane protein biogenesis... Membrane protein biogenesis at the ER: the highways and byways
    O'Keefe, Sarah; Pool, Martin R.; High, Stephen The FEBS journal, November 2022, 2022-11-00, 20221101, Volume: 289, Issue: 22
    Journal Article
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    Open access

    The Sec61 complex is the major protein translocation channel of the endoplasmic reticulum (ER), where it plays a central role in the biogenesis of membrane and secretory proteins. Whilst ...
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  • Structure of the Inhibited ... Structure of the Inhibited State of the Sec Translocon
    Gérard, Samuel F.; Hall, Belinda S.; Zaki, Afroditi M. ... Molecular cell, 08/2020, Volume: 79, Issue: 3
    Journal Article
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    Open access

    Protein secretion in eukaryotes and prokaryotes involves a universally conserved protein translocation channel formed by the Sec61 complex. Unrelated small-molecule natural products and synthetic ...
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  • Using short read sequencing... Using short read sequencing to characterise balanced reciprocal translocations in pigs
    Bouwman, Aniek C; Derks, Martijn F L; Broekhuijse, Marleen L W J ... BMC genomics, 08/2020, Volume: 21, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    A balanced constitutional reciprocal translocation (RT) is a mutual exchange of terminal segments of two non-homologous chromosomes without any loss or gain of DNA in germline cells. Carriers of ...
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  • Delineating the mechanism o... Delineating the mechanism of fragility at BCL6 breakpoint region associated with translocations in diffuse large B cell lymphoma
    Gopalakrishnan, Vidya; Roy, Urbi; Srivastava, Shikha ... Cellular and molecular life sciences : CMLS, 12/2024, Volume: 81, Issue: 1
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    Open access

    BCL6 translocation is one of the most common chromosomal translocations in cancer and results in its enhanced expression in germinal center B cells. It involves the fusion of BCL6 with any of its ...
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