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  • Use of lysophosphatidic acid un the management of benign and malignant ovarian tumors
    Požlep, Barbara ...
    Objective: To establish whether LPA determination improves the differentiationof benign from malignant ovarian tumors. - Methods: Total LPA-and LPA species in the serum were determined-using a novel ... method-in -142 patients with ultrasound (US) _ suspecious ovarian tumors and in 78 healthy women. All women underwent determination of CA125 in the serum, a vaginal US examination and morphology scoring of the tumor. Results: The levels of total LPA and its species in women with ovarian tumors were significantly higher from those in healthy women (p < 0.001). No significant difference was found in the levels of total LPA or any of its species between the women with benignand those with malignant ovarian tumors. Conclusions: Determination of serum LPA would be an appropriate test for ovarian tumor presence, especially in women of rcproductive age. The method however does not differentiate benignfrom malignant ovarian tumors.
    Source: European journal of gynaecological oncology. - ISSN 0392-2936 (Letn. 28, št. 5, 2007, str. 394-399)
    Type of material - article, component part
    Publish date - 2007
    Language - english
    COBISS.SI-ID - 23159001

source: European journal of gynaecological oncology. - ISSN 0392-2936 (Letn. 28, št. 5, 2007, str. 394-399)

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