E-resources
Peer reviewed
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Lu, Baozhao; Zhang, Ruifeng; Chen, Congdi; Jin, Liming; Xu, Jiaqi; Yang, Hongjun
Chirality (New York, N.Y.), February 2024, 2024-Feb, 2024-02-00, 20240201, Volume: 36, Issue: 2Journal Article
A series of chiral ligands were synthesized using chloramphenicol base as starting materials. These ligands were applied to the asymmetric catalytic reactions of terminal alkynes with aldehydes to obtain a propargyl alcohol product in high yield (80–94%) with excellent enantioselectivities (82–96%). The (1S, 2S)‐1‐phenyl‐2‐(1‐piperidyl)‐1,3‐propanediol ligand was applied to the asymmetric catalytic reactions of terminal alkynes with aldehydes to obtain a propargyl alcohol product in high yield (80–94%) with excellent enantioselectivities (82–96%).
