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Vasi, Fabiano; Schneider, Uwe
Medical physics (Lancaster), 20/May , Volume: 48, Issue: 5Journal Article
Purpose A nanodosimeter is a type of detector which measures single ionizations in a small gaseous volume in order to obtain ionization cluster size probability distributions for characterization of radiation types. Working nanodosimeter detectors are usually bulky machines which require a lot of space. In this work, the authors present a compact ceramic nanodosimeter detector and report on first measurements of cluster size distributions of 5 MeV alpha particles. Methods Single ionization measurements are achieved by applying a weak electric field to collect positive ions in a hole in a ceramic plate. Inside the ceramic plate, due to a strong electric field, the ions are accelerated and produce impact‐ionizations. The resulting electron avalanche is detected in a read‐out electrode. A Bayesian unfolding algorithm is then applied to the experimentally obtained cluster size distributions to reconstruct the true cluster size distributions. Results Experimentally obtained cluster size distributions by the compact nanodosimeter detector are presented. The reconstructed cluster size distributions agreed well with Monte Carlo simulated cluster size distributions for small volumes (diameter = 2.5 nm). For larger volumes, discrepancies between the reconstructed cluster size distributions and cluster size distributions from Monte Carlo simulations were observed. Conclusions For the first time, ionization cluster size probability distributions could be obtained by a small and compact nanodosimeter detector. This signifies the achievement of a critical step toward the wide application of nanodosimetric characterization of radiation types including in clinical environments.
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