Rate Limiting Step Precedes C−C Bond Formation in the Archetypical Proline-Catalyzed Intramolecular Aldol Reaction

E-resources

PDF

Full text

Peer reviewed Open access

Rate Limiting Step Precedes C−C Bond Formation in the Archetypical Proline-Catalyzed Intramolecular Aldol Reaction

Zhu, Hui; Clemente, Fernando R; Houk, K. N; Meyer, Matthew P

Journal of the American Chemical Society, 02/2009, Volume: 131, Issue: 5

Journal Article

The archetypical proline-catalyzed intramolecular aldol reaction, the Hajos-Parrish-Eder-Sauer-Wiechert reaction, has served as a model reaction for the mechanistic study of the ever-growing class of proline-catalyzed conversions. Experimental measurements of the 13C kinetic isotope effects for this reaction show conclusively that carbon−carbon bond formation is not rate-limiting.

Keep searching

Author

Zhu, Hui | Clemente, Fernando R | Houk, K. N | Meyer, Matthew P

Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.

Year	Impact factor		Edition		Category		Classification
Year	JCR	SNIP	JCR	SNIP	JCR	SNIP	JCR	SNIP

Links to authors' personal bibliographies	Links to information on researchers in the SICRIS system

Source: Personal bibliographies and: SICRIS

Upload image

Shelf entry

Adding material to shelf was successful.

Adding material to shelf failed.

It was not necessary to add the material to the shelf.

Permalink

E-mail

Impact factor

Select the library membership card:

DRS, in which the journal is indexed

Citations

Theme