Heading toward radioactive seed localization in non-palpable breast cancer surgery? A meta-analysis

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Heading toward radioactive seed localization in non-palpable breast cancer surgery? A meta-analysis

Pouw, Bas; de Wit- van der Veen, Linda J.; Stokkel, Marcel P.M.; Loo, Claudette E.; Vrancken Peeters, Marie-Jeanne T.F.D.; Valdés Olmos, Renato A.

Journal of surgical oncology, February 1, 2015, Volume: 111, Issue: 2

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Wire‐guided localization is the most commonly used technique for intraoperative localization of non‐palpable breast cancer. Radioactive seed localization (RSL) is becoming more popular and seems to be a reliable alternative for intraoperative lesion localization. The purpose of the present meta‐analysis was to evaluate the use of RSL. Primary study outcomes were irradicality and re‐excision rates. In total 3168 patients were included. The clinical adaptation shows growing confidence in RSL and further growth is expected. J. Surg. Oncol. 2015 111:185–191. © 2014 Wiley Periodicals, Inc.

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