Isocyanide‐based multicomponent reactions claim a one century‐old history of flourishing developments. On the other hand, the enormous impact of recent progresses in visible light photocatalysis has boosted the identification of new straightforward and green approaches to both new and known chemical entities. In this context, the application of visible light photocatalytic conditions to multicomponent processes has been promoting key stimulating advancements. Spanning from radical‐polar crossover pathways, to photoinduced and self‐catalyzed transformations, to reactions involving the generation of imidoyl radical species, the present literature analysis would provide a general and critical overview about the potentialities and challenges of exploiting isocyanides in visible light photocatalytic multicomponent reactions. Isocyanide‐based Multicomponent Reactions in a new light! A review about challenges, potentialities, new trends, and future directions of exploiting isocyanide unique reactivity features under visible light irradiation.