Modern agriculture necessitates the use of techniques and tools that pollute the environment less and improve the safety of food and feed production. In the field of plant protection, drones are attracting increasing attention due to their versatility and applicability in a variety of environmental and working conditions. Drone crop spraying techniques offer several advantages, including increased safety and cost effectiveness through autonomous and programmed operations based on specific schedules and routes. One of the main advantages of using drones for plant protection is their ability to monitor large areas of crops in a short amount of time. In addition to crop protection management, using drones for augmentative biocontrol facilitates the distribution of beneficial organisms to the exact locations where they are required, which can increase the effectiveness of biocontrol agents while reducing distribution costs. In this context, given the very limited commercial use of drones in the Western Balkans’ agri-food sector, the use of drones in the agri-food industry is a topic that needs to be elaborated on and highly promoted. Additionally, the specific legal regulations in Serbia that currently limit the use of drones in agriculture must be outlined. Conventional crop production is still significantly more prevalent in Serbia, but given the region’s continuous technological progress, there is no doubt that farmers’ education and future investments in precision agriculture will most likely increase the use of state-of-the-art technologies and drones in agriculture.